ANGPTL6, angiopoietin like 6, 83854

N. diseases: 48; N. variants: 4
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1551570
rs1551570
Entrez Id: 56342;83854;692229;692312
Gene Symbol: PPAN;ANGPTL6;SNORD105;PPAN-P2RY11
PPAN;ANGPTL6;SNORD105;PPAN-P2RY11
CUI: C0027404
Disease:
Narcolepsy
0.800 GeneticVariation GWASCAT Genome wide analysis of narcolepsy in China implicates novel immune loci and reveals changes in association prior to versus after the 2009 H1N1 influenza pandemic. 24204295 2013
dbSNP: rs1551570
rs1551570
Entrez Id: 56342;83854;692229;692312
Gene Symbol: PPAN;ANGPTL6;SNORD105;PPAN-P2RY11
PPAN;ANGPTL6;SNORD105;PPAN-P2RY11
CUI: C0027404
Disease:
Narcolepsy
0.800 GeneticVariation GWASDB Genome wide analysis of narcolepsy in China implicates novel immune loci and reveals changes in association prior to versus after the 2009 H1N1 influenza pandemic. 24204295 2013
dbSNP: rs1551570
rs1551570
Entrez Id: 56342;83854;692229;692312
Gene Symbol: PPAN;ANGPTL6;SNORD105;PPAN-P2RY11
PPAN;ANGPTL6;SNORD105;PPAN-P2RY11
CUI: C1834372
Disease:
Narcolepsy 1
T 0.700 GeneticVariation CLINVAR EIF3G is associated with narcolepsy across ethnicities. 25669430 2015
dbSNP: rs8109578
rs8109578
Entrez Id: 83854
Gene Symbol: ANGPTL6
ANGPTL6
CUI: C0202230
Disease:
Thyroid stimulating hormone measurement
0.700 GeneticVariation GWASCAT A genome-wide association study identifies protein quantitative trait loci (pQTLs). 18464913 2008
dbSNP: rs769022609
rs769022609
Entrez Id: 55337;83854
Gene Symbol: SHFL;ANGPTL6
SHFL;ANGPTL6
CUI: C0007766
Disease:
Intracranial Aneurysm
0.010 GeneticVariation BEFREE Here, we identified one rare nonsense variant (c.1378A>T) in the last exon of ANGPTL6 (Angiopoietin-Like 6)-which encodes a circulating pro-angiogenic factor mainly secreted from the liver-shared by the four tested affected members of a large pedigree with multiple IA-affected case subjects. 29304371 2018
dbSNP: rs6511435
rs6511435
Entrez Id: 83854
Gene Symbol: ANGPTL6
ANGPTL6
CUI: C0524620
Disease:
Metabolic Syndrome X
0.010 GeneticVariation BEFREE Moreover, the G allele of rs6511435 tended to be associated with a 20% higher risk of the metabolic syndrome (P=0.034). 19447061 2009