rs1057519720, BRAF

N. diseases: 4
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
melanoma
CUI: C0025202
Disease: melanoma
0.700 GeneticVariation CLINVAR Prospective enterprise-level molecular genotyping of a cohort of cancer patients. 25157968 2014
Carcinoma of lung
CUI: C0684249
Disease: Carcinoma of lung
0.700 CausalMutation CLINVAR Clinical, pathologic, and biologic features associated with BRAF mutations in non-small cell lung cancer. 23833300 2013
Carcinoma of lung
CUI: C0684249
Disease: Carcinoma of lung
0.700 CausalMutation CLINVAR Lung adenocarcinoma with BRAF G469L mutation refractory to vemurafenib. 24035431 2013
Carcinoma of lung
CUI: C0684249
Disease: Carcinoma of lung
0.700 CausalMutation CLINVAR Kinase-impaired BRAF mutations in lung cancer confer sensitivity to dasatinib. 22649091 2012
Carcinoma of lung
CUI: C0684249
Disease: Carcinoma of lung
0.700 CausalMutation CLINVAR Clinical characteristics of patients with lung adenocarcinomas harboring BRAF mutations. 21483012 2011
Carcinoma of lung
CUI: C0684249
Disease: Carcinoma of lung
0.700 CausalMutation CLINVAR Alterations in genes of the EGFR signaling pathway and their relationship to EGFR tyrosine kinase inhibitor sensitivity in lung cancer cell lines. 19238210 2009
Carcinoma of lung
CUI: C0684249
Disease: Carcinoma of lung
0.700 CausalMutation CLINVAR Genetic predictors of MEK dependence in non-small cell lung cancer. 19010912 2008
melanoma
CUI: C0025202
Disease: melanoma
0.700 GeneticVariation CLINVAR Analysis of BRAF mutation in primary and metastatic melanoma. 16096377 2005
Carcinoma of lung
CUI: C0684249
Disease: Carcinoma of lung
0.700 CausalMutation CLINVAR Mutations of the BRAF gene in human cancer. 12068308 2002
Carcinoma of lung
CUI: C0684249
Disease: Carcinoma of lung
0.700 CausalMutation CLINVAR Missense mutations of the BRAF gene in human lung adenocarcinoma. 12460919 2002
Carcinoma of lung
CUI: C0684249
Disease: Carcinoma of lung
0.700 CausalMutation CLINVAR BRAF and RAS mutations in human lung cancer and melanoma. 12460918 2002
Adenocarcinoma of lung (disorder)
CUI: C0152013
Disease: Adenocarcinoma of lung (disorder)
0.010 GeneticVariation BEFREE Lung adenocarcinoma with BRAF G469L mutation refractory to vemurafenib. 24035431 2013
Metastatic Lung Adenocarcinoma
CUI: C4744444
Disease: Metastatic Lung Adenocarcinoma
0.010 GeneticVariation BEFREE Here, we report the case of a patient with metastatic lung adenocarcinoma with BRAF G469L mutation refractory to vemurafenib. 24035431 2013