Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Pleural Effusion, Malignant
CUI: C0080032
Disease: Pleural Effusion, Malignant
0.030 GeneticVariation BEFREE Identification of non-small-cell lung cancer with activating EGFR mutations in malignant effusion and cerebrospinal fluid: rapid and sensitive detection of exon 19 deletion E746-A750 and exon 21 L858R mutation by immunocytochemistry. 21444121 2011
Pleural Effusion, Malignant
CUI: C0080032
Disease: Pleural Effusion, Malignant
0.030 GeneticVariation BEFREE Immunocytochemistry using two antibodies binding specifically to the major forms of mutant EGFR, L858R, and E746-A750 deletion (delE746-A750), was performed on cell blocks of malignant pleural effusion (MPE) from 78 patients with lung adenocarcinoma, who received first-line EGFR TKIs. 22525557 2012
Pleural Effusion, Malignant
CUI: C0080032
Disease: Pleural Effusion, Malignant
0.030 GeneticVariation BEFREE EGFR-L858R mutant enhances lung adenocarcinoma cell invasive ability and promotes malignant pleural effusion formation through activation of the CXCL12-CXCR4 pathway. 26338423 2015