Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Malignant neoplasm of stomach
CUI: C0024623
Disease: Malignant neoplasm of stomach
0.080 GeneticVariation BEFREE Aiming to evaluate the associations between host cell proliferation-related genetic polymorphisms and gastric cancer susceptibility, we reviewed the related studies published until 15 September 2008 and quantitatively summarized the associations of the most widely studied polymorphisms (TP53 Arg72Pro, L-myc EcoRI) using meta-analysis. 19536170 2009
Malignant neoplasm of stomach
CUI: C0024623
Disease: Malignant neoplasm of stomach
0.080 GeneticVariation BEFREE This meta-analysis suggests that Pro allele in P53 Arg72Pro is significantly associated with the increased risks of digestive tract cancers, especially for Asians, and for gastric cancer, colorectal cancer and gallbladder and pancreatic cancer. 21376265 2011
Malignant neoplasm of stomach
CUI: C0024623
Disease: Malignant neoplasm of stomach
0.080 GeneticVariation BEFREE Overall, a significant association was detected between the p53 Arg72Pro polymorphism and GC risk (Pro-allele vs. Arg-allele: OR=1.05, 95%CI=1.01-1.08; Pro/Pro vs. Arg/Arg: OR=1.13, 95%CI=1.04-1.22). 22901123 2012
Malignant neoplasm of stomach
CUI: C0024623
Disease: Malignant neoplasm of stomach
0.080 GeneticVariation BEFREE This meta-analysis suggests that p53 Arg72Pro polymorphism is associated with increased risk of gastric cancer in Asians. 22780299 2012
Malignant neoplasm of stomach
CUI: C0024623
Disease: Malignant neoplasm of stomach
0.080 GeneticVariation BEFREE This meta-analysis suggests the Pro variant of TP53 Arg72Pro contributes to gastric cancer risk in Asians. 22631671 2012
Malignant neoplasm of stomach
CUI: C0024623
Disease: Malignant neoplasm of stomach
0.080 GeneticVariation BEFREE The purpose of the present hospital-based case-control study was to investigate the association between the miR-34b/c rs4938723 and TP53 Arg72Pro polymorphisms and the risk of gastric cancer. 25190020 2014
Malignant neoplasm of stomach
CUI: C0024623
Disease: Malignant neoplasm of stomach
0.080 GeneticVariation BEFREE The p53 R72P seems not to be a potential risk factor for development of GC among Iranian patients, but our data suggest that MDM2 SNP309 might modify the risk related to GC. 25227851 2014
Malignant neoplasm of stomach
CUI: C0024623
Disease: Malignant neoplasm of stomach
0.080 GeneticVariation BEFREE The purpose of this study was to examine the role of the miR-34b/c rs4938723 and TP53 Arg72Pro polymorphisms in the susceptibility of gastric cancer. 25658980 2015