rs1342326, None

N. diseases: 9
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Adult onset asthma
CUI: C0741260
Disease: Adult onset asthma
0.010 GeneticVariation BEFREE The rs1342326 was associated with atopic, mild and adult-onset asthma and a higher level of eosinophils in peripheral blood. 31820077 2020
Allergic Reaction
CUI: C1527304
Disease: Allergic Reaction
0.700 GeneticVariation GWASDB A genome-wide association meta-analysis of self-reported allergy identifies shared and allergy-specific susceptibility loci. 23817569 2013
Asthma
CUI: C0004096
Disease: Asthma
0.840 GeneticVariation BEFREE C/C genotype of rs1342326 [OR (95% CI) 2.50 (1.33-4.69)] and A/A genotype of rs3939286 [OR (95% CI) 2.18 (1.05-4.52)] were associated with higher risk of asthma development. 31820077 2020
Asthma
CUI: C0004096
Disease: Asthma
0.840 GeneticVariation BEFREE The presence of rs1342326 polymorphism was significantly associated with a lower risk of asthma development. 28985997 2018
Asthma
CUI: C0004096
Disease: Asthma
0.840 GeneticVariation BEFREE The level of IL33 was significantly higher in asthma and MS patients compared to the control group (P< 0.001- P<0.001).The frequency distribution of the genotype in rs1342326 variant of IL-33 gene in patients with asthma, MS and healthy subjects was not significantly different (P>0.05). 30950351 2019
Asthma
CUI: C0004096
Disease: Asthma
0.840 GeneticVariation GWASDB Genome-wide association study to identify genetic determinants of severe asthma. 22561531 2012
Asthma
CUI: C0004096
Disease: Asthma
0.840 GeneticVariation GWASDB We observed associations of genomewide significance between asthma and the following single-nucleotide polymorphisms: rs3771166 on chromosome 2, implicating IL1RL1/IL18R1 (P=3×10(−9)); rs9273349 on chromosome 6, implicating HLA-DQ (P=7×10(−14)); rs1342326 on chromosome 9, flanking IL33 (P=9×10(−10)); rs744910 on chromosome 15 in SMAD3 (P=4×10(−9)); and rs2284033 on chromosome 22 in IL2RB (P=1.1×10(−8)). 20860503 2010
Asthma
CUI: C0004096
Disease: Asthma
0.840 GeneticVariation GWASCAT We observed associations of genomewide significance between asthma and the following single-nucleotide polymorphisms: rs3771166 on chromosome 2, implicating IL1RL1/IL18R1 (P=3×10(−9)); rs9273349 on chromosome 6, implicating HLA-DQ (P=7×10(−14)); rs1342326 on chromosome 9, flanking IL33 (P=9×10(−10)); rs744910 on chromosome 15 in SMAD3 (P=4×10(−9)); and rs2284033 on chromosome 22 in IL2RB (P=1.1×10(−8)). 20860503 2010
Asthma
CUI: C0004096
Disease: Asthma
0.840 GeneticVariation BEFREE We observed associations of genomewide significance between asthma and the following single-nucleotide polymorphisms: rs3771166 on chromosome 2, implicating IL1RL1/IL18R1 (P=3×10(−9)); rs9273349 on chromosome 6, implicating HLA-DQ (P=7×10(−14)); rs1342326 on chromosome 9, flanking IL33 (P=9×10(−10)); rs744910 on chromosome 15 in SMAD3 (P=4×10(−9)); and rs2284033 on chromosome 22 in IL2RB (P=1.1×10(−8)). 20860503 2010
Asthma
CUI: C0004096
Disease: Asthma
0.840 GeneticVariation GWASDB Identification of IL6R and chromosome 11q13.5 as risk loci for asthma. 21907864 2011
Behcet Syndrome
CUI: C0004943
Disease: Behcet Syndrome
0.010 GeneticVariation BEFREE Patients with BD exhibited a significantly higher prevalence of the T/G genotype of rs1342326</span> polymorphism compared with the control group. 30447310 2019
Childhood asthma
CUI: C0264408
Disease: Childhood asthma
0.010 GeneticVariation BEFREE The IL33 rs1342326 polymorphism was associated with a lower childhood asthma risk in the Tunisian population and a higher IL-33 protein expression. 28985997 2018
Eczema
CUI: C0013595
Disease: Eczema
0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
Hay fever
CUI: C0018621
Disease: Hay fever
0.010 GeneticVariation BEFREE IL-33-polymorphisms rs928413 and rs1342326 may account for an increased risk of hay fever with the age of 6 years. 27171815 2016
Multiple Sclerosis
CUI: C0026769
Disease: Multiple Sclerosis
0.010 GeneticVariation BEFREE The level of IL33 was significantly higher in asthma and MS patients compared to the control group (P< 0.001- P<0.001).The frequency distribution of the genotype in rs1342326 variant of IL-33 gene in patients with asthma, MS and healthy subjects was not significantly different (P>0.05). 30950351 2019
Wheezing
CUI: C0043144
Disease: Wheezing
0.010 GeneticVariation BEFREE Late-onset wheeze was associated with 2 IL1RL1 SNPs (rs10208293 and rs13424006), and persistent wheeze was associated with 1 IL33 SNP (rs1342326) and 1 IL1RAP SNP (rs9290936). 24568840 2014