rs2070600, AGER

N. diseases: 82
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Diabetes Mellitus
CUI: C0011849
Disease: Diabetes Mellitus
0.070 GeneticVariation BEFREE The two novel polymorphisms (1704G/T and 2184A/G) together with the G82S were shown to influence the susceptibility to MD independent of diabetes itself. 11457670 2001
Diabetes Mellitus
CUI: C0011849
Disease: Diabetes Mellitus
0.070 GeneticVariation BEFREE There were no differences among the genotypes of G1704T and G82S of the RAGE gene regarding age, duration of diabetes, body mass index, glycosylated hemoglobin (HbA1c), blood pressure, and serum lipid levels. 15798956 2005
Diabetes Mellitus
CUI: C0011849
Disease: Diabetes Mellitus
0.070 GeneticVariation BEFREE The multiple logistic regression analysis indicated that the G82S polymorphism [odds ratio (OR): 2.964, 95% confidence interval (CI): 1.013-5.46, p=0.029] and diabetes duration (OR: 1.013, 95% CI: 1.007-1.02, p<0.001) were independent risk factors for DR. 19542745 2009
Diabetes Mellitus
CUI: C0011849
Disease: Diabetes Mellitus
0.070 GeneticVariation BEFREE Six articles investigated the -429T/C polymorphism, 7 publications were associated with the -374T/A polymorphism and 5 studies were associated with Gly82Ser in DR. For the -429T/C variant, we found no significant difference between DR patients and those with diabetes without retinopathy. 22354095 2012
Diabetes Mellitus
CUI: C0011849
Disease: Diabetes Mellitus
0.070 GeneticVariation BEFREE Overall results detected no significant association of polymorphisms T-429C, T-374A and Gly82Ser with diabetes risk. 22402134 2012
Diabetes Mellitus
CUI: C0011849
Disease: Diabetes Mellitus
0.070 GeneticVariation BEFREE The present study revealed that the RAGE G82S polymorphism was associated with chronic periodontitis in the non-DM group but not in the DM group. 25988707 2015
Diabetes Mellitus
CUI: C0011849
Disease: Diabetes Mellitus
0.070 GeneticVariation BEFREE We found that Gly82Ser in RAGE showed significant association with DR. More studies with larger sample sizes that control for important risk factors, such as duration of diabetes, are needed to validate our findings. 27684793 2016