Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Diabetes Mellitus, Non-Insulin-Dependent
0.100 GeneticVariation BEFREE We aimed to investigate the roles of RAGE, AGEs and the Gly82Ser polymorphism of RAGE in mild cognitive impairment (MCI) among type 2 diabetes patients. 26745632 2016
Diabetes Mellitus, Non-Insulin-Dependent
0.100 GeneticVariation BEFREE The -429 T/C and Gly82Ser RAGE polymorphisms were found to be significantly associated with the development of macrovascular and microvascular complications, respectively, in T2DM subjects while -374A allele showed reduced risk towards the development of macrovascular complications. 24418399 2014
Diabetes Mellitus, Non-Insulin-Dependent
0.100 GeneticVariation BEFREE To investigate the association between diabetic retinopathy (DR) in type 2 diabetes mellitus and three polymorphisms of the receptor for advanced glycation end products (RAGE) gene, -429T/C, -374T/A and Gly82Ser. 22354095 2012
Diabetes Mellitus, Non-Insulin-Dependent
0.100 GeneticVariation BEFREE A meta-analysis was performed to assess the associations of the receptor for advanced glycation end products (RAGE) gene polymorphisms [Gly82Ser (rs2070600), 1704G/T (rs184003), 429T/C (rs1800625)] with type 2 diabetes mellitus (T2DM), diabetic retinopathy (DR) and diabetic nephropathy (DN). 22475522 2012
Diabetes Mellitus, Non-Insulin-Dependent
0.100 GeneticVariation BEFREE The aim of this study is to evaluate the association of the G82S polymorphism with the severity of coronary artery disease (CAD) in patients with or without type 2 diabetes mellitus (T2DM). 21521347 2011
Diabetes Mellitus, Non-Insulin-Dependent
0.100 GeneticVariation BEFREE We previously reported the association of the Z-2 allele of the promoter dinucleotide repeat in the Aldose reductase (ALR2) gene, the (CCTTT)₁₅ allele in the promoter of inductible nitric oxide synthase (iNOS) gene, and the (GT)₁₃ promoter polymorphism in the tumor necrosis factor β (TNFB) gene with an increased risk for diabetic retinopathy (DR), and the Gly82Ser polymorphism in the receptor for advanced glycation end products (RAGE) gene and the (GT)₉ allele of the TNFB gene with low-risk for DR in a hospital-based self-reported type 2 diabetes mellitus (T2DM) patients. 21067489 2010
Diabetes Mellitus, Non-Insulin-Dependent
0.100 GeneticVariation BEFREE This study confirms significant association of one polymorphism only (rs2070600 in RAGE) with DR in an Indian population which had T2DM. 21067572 2010
Diabetes Mellitus, Non-Insulin-Dependent
0.100 GeneticVariation BEFREE G82S polymorphism in the RAGE gene is associated with DR and G-A haplotype containing 1704G and 82S allele might be a genetic marker of DR in Chinese T2DM patients. 19542745 2009
Diabetes Mellitus, Non-Insulin-Dependent
0.100 GeneticVariation BEFREE G82S and -429 T/C polymorphisms of RAGE were associated with the circulating levels of esRAGE but not with CAD in Chinese patients with T2DM. 19766904 2009
Diabetes Mellitus, Non-Insulin-Dependent
0.100 GeneticVariation BEFREE We investigated the relationship of 3 polymorphisms (rs1800625, rs1800624 and rs2070600) in the AGER gene and their haplotypes with T2DM as well as insulin resistance. 18796298 2008
Diabetes Mellitus, Non-Insulin-Dependent
0.100 GeneticVariation BEFREE This study aims to investigate the frequency of Gly82Ser polymorphism in exon 3 of the receptor for AGE (RAGE) gene and its association with DR in Asian Indian patients who have type II diabetes. 12477623 2003
Diabetes Mellitus, Non-Insulin-Dependent
0.100 GeneticVariation BEFREE Statistically significant differences in allele frequencies between the NIDDM and the nondiabetic groups were observed for the G82S and 2245G/A polymorphisms (P =.047 and .032, respectively). 11586486 2001