| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
NLR family pyrin domain containing 3 | 0.361 | 0.962 | 8.1E-04 |
|
group | 0.110 | None | < 0.001 | 0 | 0 | 2007 | 2007 | ||||||||
|
AKT serine/threonine kinase 1 | 0.311 | 0.962 | 0.98 |
|
group | 0.110 | None | 1.000 | 0 | 0 | 2014 | 2014 | ||||||||
|
Rac family small GTPase 1 | 0.429 | 0.962 | 0.76 |
|
group | 0.450 | strong | 1.000 | 0 | 0 | 2008 | 2019 | ||||||||
|
aryl hydrocarbon receptor | 0.410 | 0.923 | 1.00 |
|
group | 0.100 | None | 0 | 0 | |||||||||||
|
filamin B | 0.458 | 0.923 | 6.1E-10 |
|
group | 0.100 | None | 0 | 0 | |||||||||||
|
KRAS proto-oncogene, GTPase | 0.320 | 0.923 | 7.9E-04 |
|
group | 0.100 | None | 0 | 0 | |||||||||||
|
arylsulfatase A | 0.448 | 0.923 | 1.1E-11 |
|
group | 0.100 | None | 0 | 0 | |||||||||||
|
matrix metallopeptidase 2 | 0.333 | 0.923 | 0.84 |
|
group | 0.100 | None | 0 | 0 | |||||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | 0.292 | 0.923 | 1.00 |
|
group | 0.120 | None | 1.000 | 0 | 0 | 2017 | 2019 | ||||||||
|
ATR serine/threonine kinase | 0.456 | 0.923 | 3.5E-09 |
|
group | 0.200 | None | 1.000 | 0 | 0 | 1995 | 2017 | ||||||||
|
mitogen-activated protein kinase 1 | 0.330 | 0.923 | 1.00 |
|
group | 0.110 | None | 1.000 | 0 | 0 | 2018 | 2018 | ||||||||
|
phosphatase and tensin homolog | 0.305 | 0.923 | 0.26 |
|
group | 0.450 | None | 1.000 | 0 | 0 | 2001 | 2019 | ||||||||
|
actin beta | 0.325 | 0.923 | 0.99 |
|
group | 0.200 | None | 1.000 | 0 | 0 | 1999 | 2019 | ||||||||
|
brain derived neurotrophic factor | 0.345 | 0.923 | 0.66 |
|
group | 0.500 | None | 1.000 | 0 | 0 | 1994 | 2018 | ||||||||
|
BRCA1 DNA repair associated | 0.367 | 0.923 | 9.2E-29 |
|
group | 0.400 | limited | 0 | 0 | |||||||||||
|
valosin containing protein | 0.469 | 0.923 | 1.00 |
|
group | 0.100 | None | 0 | 0 | |||||||||||
|
ERCC excision repair 8, CSA ubiquitin ligase complex subunit | 0.551 | 0.885 | 2.8E-15 |
|
group | 0.110 | None | 1.000 | 0 | 0 | 2013 | 2013 | ||||||||
|
catenin beta 1 | 0.303 | 0.885 | 1.00 |
|
group | 0.190 | None | 1.000 | 0 | 0 | 2013 | 2019 | ||||||||
|
elastin | 0.415 | 0.885 | 2.1E-14 |
|
group | 0.120 | None | 1.000 | 0 | 0 | 1996 | 1998 | ||||||||
|
enhancer of zeste 2 polycomb repressive complex 2 subunit | 0.376 | 0.885 | 1.00 |
|
group | 0.130 | None | 1.000 | 0 | 0 | 2017 | 2019 | ||||||||
|
FA complementation group D2 | 0.479 | 0.885 | 1.1E-30 |
|
group | 0.100 | None | 0 | 0 | |||||||||||
|
fibroblast growth factor receptor 1 | 0.362 | 0.885 | 1.00 |
|
group | 0.100 | None | 0 | 0 | |||||||||||
|
folate receptor alpha | 0.522 | 0.885 | 0.13 |
|
group | 0.400 | None | 1.000 | 0 | 0 | 2011 | 2011 | ||||||||
|
Fos proto-oncogene, AP-1 transcription factor subunit | 0.411 | 0.885 | 0.26 |
|
group | 0.110 | None | 1.000 | 0 | 0 | 2013 | 2013 | ||||||||
|
nucleoporin 62 | 0.470 | 0.885 | 0.95 |
|
group | 0.400 | limited | 1.000 | 0 | 0 | 2006 | 2006 |