Source: LHGDN

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7124
Gene Symbol: TNF
TNF
tumor necrosis factor 0.231 0.962 0.80
CUI: C0016059
Disease: Fibrosis
Fibrosis
phenotype 0.340 None 1.000 4 0 2002 2008
Entrez Id: 7157
Gene Symbol: TP53
TP53
tumor protein p53 0.236 0.962 0.53
CUI: C0016059
Disease: Fibrosis
Fibrosis
phenotype 0.010 None 1.000 1 0 2003 2003
Entrez Id: 3569
Gene Symbol: IL6
IL6
interleukin 6 0.248 0.962 0.32
CUI: C0016059
Disease: Fibrosis
Fibrosis
phenotype 0.030 None 1.000 3 0 2002 2008
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
vascular endothelial growth factor A 0.266 0.923 2.4E-05
CUI: C0016059
Disease: Fibrosis
Fibrosis
phenotype 0.030 None 1.000 3 0 2004 2008
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
interleukin 1 beta 0.276 0.962 0.13
CUI: C0016059
Disease: Fibrosis
Fibrosis
phenotype 0.310 None 1.000 1 0 2007 2016
Entrez Id: 3586
Gene Symbol: IL10
IL10
interleukin 10 0.281 0.923 5.9E-03
CUI: C0016059
Disease: Fibrosis
Fibrosis
phenotype 0.020 None 1.000 2 0 2004 2008
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
transforming growth factor beta 1 0.287 0.962 3.7E-02
CUI: C0016059
Disease: Fibrosis
Fibrosis
phenotype 0.600 None 1.000 19 0 1999 2019
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
interferon gamma 0.288 0.962 0.47
CUI: C0016059
Disease: Fibrosis
Fibrosis
phenotype 0.030 None 1.000 3 0 2002 2006
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
epidermal growth factor receptor 0.295 0.885 0.37
CUI: C0016059
Disease: Fibrosis
Fibrosis
phenotype 0.010 None 1.000 1 0 2008 2008
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
C-X-C motif chemokine ligand 8 0.310 0.962 2.7E-04
CUI: C0016059
Disease: Fibrosis
Fibrosis
phenotype 0.010 None 1.000 1 0 2008 2008
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
prostaglandin-endoperoxide synthase 2 0.314 0.962 1.00
CUI: C0016059
Disease: Fibrosis
Fibrosis
phenotype 0.510 None 1.000 1 0 2002 2008
Entrez Id: 3479
Gene Symbol: IGF1
IGF1
insulin like growth factor 1 0.318 0.885 0.27
CUI: C0016059
Disease: Fibrosis
Fibrosis
phenotype 0.010 None 1.000 1 0 2003 2003
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
signal transducer and activator of transcription 3 0.320 0.923 1.00
CUI: C0016059
Disease: Fibrosis
Fibrosis
phenotype 0.310 None 1.000 1 0 2003 2014
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
C-C motif chemokine ligand 2 0.321 0.962 0.61
CUI: C0016059
Disease: Fibrosis
Fibrosis
phenotype 0.020 None 1.000 2 0 2003 2004
Entrez Id: 1636
Gene Symbol: ACE
ACE
angiotensin I converting enzyme 0.328 0.923 1.0E-37
CUI: C0016059
Disease: Fibrosis
Fibrosis
phenotype 0.020 None 1.000 2 0 2003 2007
Entrez Id: 5594
Gene Symbol: MAPK1
MAPK1
mitogen-activated protein kinase 1 0.330 0.923 1.00
CUI: C0016059
Disease: Fibrosis
Fibrosis
phenotype 0.010 None 1.000 1 0 2008 2008
Entrez Id: 595
Gene Symbol: CCND1
CCND1
cyclin D1 0.344 0.923 0.89
CUI: C0016059
Disease: Fibrosis
Fibrosis
phenotype 0.010 None 1.000 1 0 2003 2003
Entrez Id: 6696
Gene Symbol: SPP1
SPP1
secreted phosphoprotein 1 0.353 0.885 2.1E-06
CUI: C0016059
Disease: Fibrosis
Fibrosis
phenotype 0.020 None 1.000 2 0 2003 2005
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1
serpin family E member 1 0.359 0.885 4.4E-02
CUI: C0016059
Disease: Fibrosis
Fibrosis
phenotype 0.030 None 1.000 3 0 2002 2005
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1
intercellular adhesion molecule 1 0.364 0.962 3.5E-02
CUI: C0016059
Disease: Fibrosis
Fibrosis
phenotype 0.210 None 1.000 1 0 2008 2012
Entrez Id: 183
Gene Symbol: AGT
AGT
angiotensinogen 0.367 0.923 5.0E-08
CUI: C0016059
Disease: Fibrosis
Fibrosis
phenotype 0.510 None 1.000 1 0 2002 2015
Entrez Id: 355
Gene Symbol: FAS
FAS
Fas cell surface death receptor 0.372 0.923 0.81
CUI: C0016059
Disease: Fibrosis
Fibrosis
phenotype 0.020 None 1.000 2 0 2005 2009
Entrez Id: 7431
Gene Symbol: VIM
VIM
vimentin 0.372 0.846 0.71
CUI: C0016059
Disease: Fibrosis
Fibrosis
phenotype 0.010 None 1.000 1 0 2008 2008
Entrez Id: 3082
Gene Symbol: HGF
HGF
hepatocyte growth factor 0.374 0.885 1.00
CUI: C0016059
Disease: Fibrosis
Fibrosis
phenotype 0.010 None 1.000 1 0 2002 2002
Entrez Id: 1432
Gene Symbol: MAPK14
MAPK14
mitogen-activated protein kinase 14 0.379 0.923 0.37
CUI: C0016059
Disease: Fibrosis
Fibrosis
phenotype 0.020 None 1.000 2 0 2003 2007