Source: ANIMAL_MODELS

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7124
Gene Symbol: TNF
TNF
tumor necrosis factor 0.231 0.962 0.80
CUI: C0021368
Disease: Inflammation
Inflammation
phenotype 0.600 None 1.000 2 0 2001 2016
Entrez Id: 3569
Gene Symbol: IL6
IL6
interleukin 6 0.248 0.962 0.32
CUI: C0021368
Disease: Inflammation
Inflammation
phenotype 0.570 None 1.000 1 0 2001 2015
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
interleukin 1 beta 0.276 0.962 0.13
CUI: C0021368
Disease: Inflammation
Inflammation
phenotype 0.570 None 1.000 5 0 1999 2017
Entrez Id: 3586
Gene Symbol: IL10
IL10
interleukin 10 0.281 0.923 5.9E-03
CUI: C0021368
Disease: Inflammation
Inflammation
phenotype 0.550 None 1.000 1 0 2001 2013
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
epidermal growth factor receptor 0.295 0.885 0.37
CUI: C0021368
Disease: Inflammation
Inflammation
phenotype 0.200 None 1.000 1 0 2012 2012
Entrez Id: 1401
Gene Symbol: CRP
CRP
C-reactive protein 0.299 0.962 3.7E-03
CUI: C0021368
Disease: Inflammation
Inflammation
phenotype 0.600 None 1.000 1 0 2001 2011
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
prostaglandin-endoperoxide synthase 2 0.314 0.962 1.00
CUI: C0021368
Disease: Inflammation
Inflammation
phenotype 0.570 None 1.000 3 0 2001 2009
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma 0.320 0.885 1.4E-06
CUI: C0021368
Disease: Inflammation
Inflammation
phenotype 0.200 None 1.000 1 0 2007 2007
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
C-C motif chemokine ligand 2 0.321 0.962 0.61
CUI: C0021368
Disease: Inflammation
Inflammation
phenotype 0.540 None 1.000 1 0 2003 2011
Entrez Id: 2475
Gene Symbol: MTOR
MTOR
mechanistic target of rapamycin kinase 0.343 0.885 1.00
CUI: C0021368
Disease: Inflammation
Inflammation
phenotype 0.200 None 1.000 1 0 2013 2013
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
ATP binding cassette subfamily B member 1 0.344 0.885 1.3E-05
CUI: C0021368
Disease: Inflammation
Inflammation
phenotype 0.210 None 1.000 1 0 2007 2015
Entrez Id: 627
Gene Symbol: BDNF
BDNF
brain derived neurotrophic factor 0.345 0.923 0.66
CUI: C0021368
Disease: Inflammation
Inflammation
phenotype 0.530 None 1.000 1 0 2003 2010
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
peroxisome proliferator activated receptor gamma 0.358 0.885 2.9E-02
CUI: C0021368
Disease: Inflammation
Inflammation
phenotype 0.520 None 1.000 2 0 2006 2011
Entrez Id: 7097
Gene Symbol: TLR2
TLR2
toll like receptor 2 0.361 0.923 1.0E-06
CUI: C0021368
Disease: Inflammation
Inflammation
phenotype 0.560 None 1.000 1 0 2005 2012
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1
intercellular adhesion molecule 1 0.364 0.962 3.5E-02
CUI: C0021368
Disease: Inflammation
Inflammation
phenotype 0.550 None 1.000 1 0 2002 2013
Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN
interleukin 1 receptor antagonist 0.373 0.923 3.1E-02
CUI: C0021368
Disease: Inflammation
Inflammation
phenotype 0.520 None 1.000 1 0 2003 2015
Entrez Id: 2247
Gene Symbol: FGF2
FGF2
fibroblast growth factor 2 0.383 0.923 1.8E-02
CUI: C0021368
Disease: Inflammation
Inflammation
phenotype 0.510 None 1.000 1 0 2002 2010
Entrez Id: 4803
Gene Symbol: NGF
NGF
nerve growth factor 0.391 0.885 0.82
CUI: C0021368
Disease: Inflammation
Inflammation
phenotype 0.510 None 1.000 1 0 2000 2009
Entrez Id: 1234
Gene Symbol: CCR5
CCR5
C-C motif chemokine receptor 5 (gene/pseudogene) 0.398 0.885 4.3E-10
CUI: C0021368
Disease: Inflammation
Inflammation
phenotype 0.200 None 1.000 1 0 2005 2005
Entrez Id: 6352
Gene Symbol: CCL5
CCL5
C-C motif chemokine ligand 5 0.403 0.885 1.8E-03
CUI: C0021368
Disease: Inflammation
Inflammation
phenotype 0.220 None 1.000 1 0 2003 2007
Entrez Id: 3240
Gene Symbol: HP
HP
haptoglobin 0.412 0.885 1.7E-05
CUI: C0021368
Disease: Inflammation
Inflammation
phenotype 0.200 None 1.000 1 0 2003 2003
Entrez Id: 4282
Gene Symbol: MIF
MIF
macrophage migration inhibitory factor 0.412 0.885 1.2E-02
CUI: C0021368
Disease: Inflammation
Inflammation
phenotype 0.560 None 1.000 1 0 2003 2010
Entrez Id: 2152
Gene Symbol: F3
F3
coagulation factor III, tissue factor 0.415 0.846 1.9E-02
CUI: C0021368
Disease: Inflammation
Inflammation
phenotype 0.200 None 1.000 1 0 2015 2015
Entrez Id: 796
Gene Symbol: CALCA
CALCA
calcitonin related polypeptide alpha 0.416 0.923 1.6E-02
CUI: C0021368
Disease: Inflammation
Inflammation
phenotype 0.500 None 1.000 1 0 2001 2011
Entrez Id: 3600
Gene Symbol: IL15
IL15
interleukin 15 0.422 0.846 0.71
CUI: C0021368
Disease: Inflammation
Inflammation
phenotype 0.220 None 1.000 1 0 2002 2003