|
| Entrez Id: |
1495 |
| Gene Symbol: |
CTNNA1 |
CTNNA1
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.300 |
Biomarker |
CLINGEN |
|
|
|
|
| Entrez Id: |
22909 |
| Gene Symbol: |
FAN1 |
FAN1
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.300 |
Biomarker |
CLINGEN |
A genetic screen identifies FAN1, a Fanconi anemia-associated nuclease necessary for DNA interstrand crosslink repair.
|
20603073 |
2010 |
|
| Entrez Id: |
79728 |
| Gene Symbol: |
PALB2 |
PALB2
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.300 |
Biomarker |
CLINGEN |
A pathology atlas of the human cancer transcriptome.
|
28818916 |
2017 |
|
| Entrez Id: |
580 |
| Gene Symbol: |
BARD1 |
BARD1
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.300 |
Biomarker |
CLINGEN |
Adenosine nucleotide modulates the physical interaction between hMSH2 and BRCA1.
|
11498787 |
2001 |
|
| Entrez Id: |
11200 |
| Gene Symbol: |
CHEK2 |
CHEK2
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.300 |
Biomarker |
CLINGEN |
Alterations of Chk1 and Chk2 expression in colon cancer.
|
18679694 |
2008 |
|
| Entrez Id: |
2956 |
| Gene Symbol: |
MSH6 |
MSH6
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.640 |
Biomarker |
CLINGEN |
Association of hereditary nonpolyposis colorectal cancer-related tumors displaying low microsatellite instability with MSH6 germline mutations.
|
10521294 |
1999 |
|
| Entrez Id: |
4437 |
| Gene Symbol: |
MSH3 |
MSH3
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.300 |
Biomarker |
CLINGEN |
Association of low-risk MSH3 and MSH2 variant alleles with Lynch syndrome: probability of synergistic effects.
|
21128252 |
2011 |
|
| Entrez Id: |
27030 |
| Gene Symbol: |
MLH3 |
MLH3
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.500 |
Biomarker |
CLINGEN |
Biochemical characterization of MLH3 missense mutations does not reveal an apparent role of MLH3 in Lynch syndrome.
|
19156873 |
2009 |
|
| Entrez Id: |
4436 |
| Gene Symbol: |
MSH2 |
MSH2
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.900 |
Biomarker |
CLINGEN |
Cancer risks for MLH1 and MSH2 mutation carriers.
|
23255516 |
2013 |
|
| Entrez Id: |
472 |
| Gene Symbol: |
ATM |
ATM
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.300 |
Biomarker |
CLINGEN |
Cancer Susceptibility Gene Mutations in Individuals With Colorectal Cancer.
|
28135145 |
2017 |
|
| Entrez Id: |
11200 |
| Gene Symbol: |
CHEK2 |
CHEK2
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.300 |
Biomarker |
CLINGEN |
Cancer Susceptibility Gene Mutations in Individuals With Colorectal Cancer.
|
28135145 |
2017 |
|
| Entrez Id: |
11200 |
| Gene Symbol: |
CHEK2 |
CHEK2
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.300 |
Biomarker |
CLINGEN |
CHEK2 1100delC is a susceptibility allele for HNPCC-related colorectal cancer.
|
18676774 |
2008 |
|
| Entrez Id: |
11200 |
| Gene Symbol: |
CHEK2 |
CHEK2
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.300 |
Biomarker |
CLINGEN |
CHEK2 mutations and HNPCC-related colorectal cancer.
|
19876921 |
2010 |
|
| Entrez Id: |
1027 |
| Gene Symbol: |
CDKN1B |
CDKN1B
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.300 |
Biomarker |
CLINGEN |
Comparative effects of overexpression of p27Kip1 and p21Cip1/Waf1 on growth and differentiation in human colon carcinoma cells.
|
9926925 |
1999 |
|
| Entrez Id: |
27030 |
| Gene Symbol: |
MLH3 |
MLH3
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.500 |
Biomarker |
CLINGEN |
Conditional nuclear localization of hMLH3 suggests a minor activity in mismatch repair and supports its role as a low-risk gene in HNPCC.
|
17203173 |
2007 |
|
| Entrez Id: |
27030 |
| Gene Symbol: |
MLH3 |
MLH3
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.500 |
Biomarker |
CLINGEN |
Contributions by MutL homologues Mlh3 and Pms2 to DNA mismatch repair and tumor suppression in the mouse.
|
16204034 |
2005 |
|
| Entrez Id: |
22909 |
| Gene Symbol: |
FAN1 |
FAN1
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.300 |
Biomarker |
CLINGEN |
Deficiency of FANCD2-associated nuclease KIAA1018/FAN1 sensitizes cells to interstrand crosslinking agents.
|
20603016 |
2010 |
|
| Entrez Id: |
5395 |
| Gene Symbol: |
PMS2 |
PMS2
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.640 |
Biomarker |
CLINGEN |
Deficient expression of DNA repair enzymes in early progression to sporadic colon cancer.
|
22494821 |
2012 |
|
| Entrez Id: |
2052 |
| Gene Symbol: |
EPHX1 |
EPHX1
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.300 |
Biomarker |
CLINGEN |
Distribution of microsomal epoxide hydrolase in humans: an immunohistochemical study in normal tissues, and benign and malignant tumours.
|
11758809 |
2001 |
|
| Entrez Id: |
11200 |
| Gene Symbol: |
CHEK2 |
CHEK2
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.300 |
Biomarker |
CLINGEN |
DNA damage during reoxygenation elicits a Chk2-dependent checkpoint response.
|
16478982 |
2006 |
|
| Entrez Id: |
11200 |
| Gene Symbol: |
CHEK2 |
CHEK2
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.300 |
Biomarker |
CLINGEN |
DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis.
|
15829956 |
2005 |
|
| Entrez Id: |
1027 |
| Gene Symbol: |
CDKN1B |
CDKN1B
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.300 |
Biomarker |
CLINGEN |
Down-regulation of p27 is associated with development of colorectal adenocarcinoma metastases.
|
9736017 |
1998 |
|
| Entrez Id: |
472 |
| Gene Symbol: |
ATM |
ATM
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.300 |
Biomarker |
CLINGEN |
Downregulated Ku70 and ATM associated to poor prognosis in colorectal cancer among Chinese patients.
|
25368522 |
2014 |
|
| Entrez Id: |
999 |
| Gene Symbol: |
CDH1 |
CDH1
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.300 |
Biomarker |
CLINGEN |
E-cadherin germline mutations in familial gastric cancer.
|
9537325 |
1998 |
|
| Entrez Id: |
5395 |
| Gene Symbol: |
PMS2 |
PMS2
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.640 |
Biomarker |
CLINGEN |
Endonucleolytic function of MutLalpha in human mismatch repair.
|
16873062 |
2006 |