| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
angiotensin I converting enzyme | 0.328 | 0.923 | 1.0E-37 |
|
disease | 0.600 | None | 0.914 | 146 | 6 | 1994 | 2019 | ||||||||
|
renin | 0.370 | 0.923 | 2.4E-07 |
|
disease | 0.300 | None | 0.990 | 97 | 0 | 1995 | 2020 | ||||||||
|
albumin | 0.317 | 0.962 | 0.64 |
|
disease | 0.600 | None | 0.960 | 96 | 3 | 1989 | 2020 | ||||||||
|
transforming growth factor beta 1 | 0.287 | 0.962 | 3.7E-02 |
|
disease | 0.600 | None | 0.990 | 91 | 1 | 1996 | 2019 | ||||||||
|
angiotensinogen | 0.367 | 0.923 | 5.0E-08 |
|
disease | 0.400 | None | 0.929 | 68 | 4 | 1996 | 2020 | ||||||||
|
solute carrier family 5 member 2 | 0.499 | 0.769 | 4.9E-14 |
|
disease | 0.100 | None | 0.955 | 44 | 0 | 2013 | 2020 | ||||||||
|
tumor necrosis factor | 0.231 | 0.962 | 0.80 |
|
disease | 0.300 | None | 0.957 | 44 | 3 | 1997 | 2020 | ||||||||
|
nuclear factor, erythroid 2 like 2 | 0.357 | 0.885 | 3.6E-03 |
|
disease | 0.600 | None | 1.000 | 40 | 0 | 2010 | 2020 | ||||||||
|
vascular endothelial growth factor A | 0.266 | 0.923 | 2.4E-05 |
|
disease | 0.400 | None | 0.976 | 39 | 1 | 1999 | 2019 | ||||||||
|
GA binding protein transcription factor subunit alpha | 0.379 | 0.885 | 1.00 |
|
disease | 0.100 | None | 1.000 | 33 | 0 | 2010 | 2019 | ||||||||
|
aldo-keto reductase family 1 member B | 0.491 | 0.885 | 2.0E-05 |
|
disease | 0.100 | None | 0.971 | 32 | 1 | 1997 | 2019 | ||||||||
|
diabetic nephropathy | 0.678 | 0.500 |
|
disease | 0.100 | None | 1.000 | 32 | 0 | 2006 | 2020 | |||||||||
|
nitric oxide synthase 3 | 0.378 | 0.885 | 6.7E-07 |
|
disease | 0.600 | None | 0.941 | 32 | 7 | 2000 | 2019 | ||||||||
|
adiponectin, C1Q and collagen domain containing | 0.376 | 0.885 | 4.6E-09 |
|
disease | 0.400 | None | 0.970 | 32 | 8 | 2004 | 2019 | ||||||||
|
cellular communication network factor 2 | 0.399 | 0.846 | 5.0E-04 |
|
disease | 0.300 | None | 0.974 | 31 | 0 | 1998 | 2020 | ||||||||
|
methylenetetrahydrofolate reductase | 0.337 | 0.885 | 3.2E-10 |
|
disease | 0.100 | None | 0.967 | 30 | 3 | 1999 | 2019 | ||||||||
|
C-C motif chemokine ligand 2 | 0.321 | 0.962 | 0.61 |
|
disease | 0.600 | None | 0.969 | 29 | 1 | 2000 | 2020 | ||||||||
|
angiotensin II receptor type 1 | 0.423 | 0.846 | 5.3E-04 |
|
disease | 0.300 | None | 0.867 | 28 | 1 | 1996 | 2019 | ||||||||
|
apolipoprotein E | 0.338 | 0.962 | 1.9E-03 |
|
disease | 0.100 | None | 0.929 | 28 | 2 | 1996 | 2019 | ||||||||
|
interleukin 6 | 0.248 | 0.962 | 0.32 |
|
disease | 0.300 | None | 1.000 | 28 | 5 | 2002 | 2020 | ||||||||
|
carnosine dipeptidase 1 | 0.656 | 0.538 | 1.2E-09 |
|
disease | 0.400 | None | 0.929 | 27 | 1 | 2005 | 2019 | ||||||||
|
sirtuin 1 | 0.378 | 0.885 | 8.7E-02 |
|
disease | 0.100 | None | 1.000 | 26 | 2 | 2011 | 2020 | ||||||||
|
NLR family pyrin domain containing 3 | 0.361 | 0.962 | 8.1E-04 |
|
disease | 0.100 | None | 0.960 | 25 | 0 | 2015 | 2020 | ||||||||
|
toll like receptor 4 | 0.321 | 0.962 | 4.6E-09 |
|
disease | 0.100 | None | 0.920 | 25 | 4 | 2012 | 2020 | ||||||||
|
dipeptidyl peptidase 4 | 0.420 | 0.808 | 7.3E-09 |
|
disease | 0.100 | None | 0.917 | 24 | 0 | 2013 | 2020 |