| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
APC regulator of WNT signaling pathway | 0.373 | 0.962 | 1.00 |
|
group | 0.400 | None | 0.967 | 120 | 5 | 1990 | 2018 | ||||||||
|
tumor protein p53 | 0.236 | 0.962 | 0.53 |
|
group | 0.400 | None | 0.911 | 146 | 4 | 1986 | 2020 | ||||||||
|
mutY DNA glycosylase | 0.521 | 0.769 | 1.3E-18 |
|
group | 0.100 | None | 1.000 | 29 | 3 | 2002 | 2017 | ||||||||
|
C-reactive protein | 0.299 | 0.962 | 3.7E-03 |
|
group | 0.080 | None | 0.875 | 8 | 3 | 2000 | 2018 | ||||||||
|
UDP glucuronosyltransferase family 1 member A6 | 0.560 | 0.654 | 3.0E-07 |
|
group | 0.030 | None | 0.333 | 3 | 3 | 2005 | 2012 | ||||||||
|
glial cells missing transcription factor 2 | 0.647 | 0.538 | 9.1E-04 |
|
group | 0.030 | None | 1.000 | 3 | 3 | 2002 | 2004 | ||||||||
|
solute carrier family 19 member 1 | 0.523 | 0.692 | 6.5E-06 |
|
group | 0.310 | None | 1.000 | 2 | 3 | 2007 | 2011 | ||||||||
|
FTO alpha-ketoglutarate dependent dioxygenase | 0.486 | 0.885 | 8.4E-08 |
|
group | 0.010 | None | 1.000 | 1 | 3 | 2012 | 2012 | ||||||||
|
catenin beta 1 | 0.303 | 0.885 | 1.00 |
|
group | 0.400 | None | 0.959 | 97 | 2 | 1996 | 2019 | ||||||||
|
KRAS proto-oncogene, GTPase | 0.320 | 0.923 | 7.9E-04 |
|
group | 0.400 | None | 0.944 | 90 | 2 | 1991 | 2020 | ||||||||
|
B-Raf proto-oncogene, serine/threonine kinase | 0.319 | 0.846 | 1.00 |
|
group | 0.100 | None | 0.981 | 52 | 2 | 2002 | 2019 | ||||||||
|
prostaglandin-endoperoxide synthase 2 | 0.314 | 0.962 | 1.00 |
|
group | 0.100 | None | 0.913 | 46 | 2 | 1994 | 2019 | ||||||||
|
potassium inwardly rectifying channel subfamily J member 5 | 0.560 | 0.577 | 3.4E-04 |
|
group | 0.400 | None | 1.000 | 34 | 2 | 2012 | 2019 | ||||||||
|
aryl hydrocarbon receptor interacting protein | 0.517 | 0.769 | 0.36 |
|
group | 0.400 | None | 1.000 | 15 | 2 | 2007 | 2019 | ||||||||
|
methylenetetrahydrofolate reductase | 0.337 | 0.885 | 3.2E-10 |
|
group | 0.100 | None | 0.846 | 13 | 2 | 1999 | 2013 | ||||||||
|
mutS homolog 6 | 0.462 | 0.731 | 3.7E-05 |
|
group | 0.080 | None | 1.000 | 8 | 2 | 2006 | 2019 | ||||||||
|
epoxide hydrolase 1 | 0.500 | 0.846 | 3.2E-09 |
|
group | 0.050 | None | 0.800 | 5 | 2 | 2001 | 2007 | ||||||||
|
8-oxoguanine DNA glycosylase | 0.453 | 0.808 | 3.9E-12 |
|
group | 0.050 | None | 0.800 | 5 | 2 | 2005 | 2011 | ||||||||
|
dopamine receptor D2 | 0.436 | 0.846 | 0.75 |
|
group | 0.030 | None | 1.000 | 3 | 2 | 2001 | 2016 | ||||||||
|
luteinizing hormone/choriogonadotropin receptor | 0.528 | 0.692 | 5.3E-08 |
|
group | 0.030 | None | 1.000 | 3 | 2 | 2006 | 2015 | ||||||||
|
prostaglandin-endoperoxide synthase 1 | 0.460 | 0.885 | 6.2E-07 |
|
group | 0.030 | None | 1.000 | 3 | 2 | 2001 | 2007 | ||||||||
|
glutathione S-transferase pi 1 | 0.383 | 0.923 | 1.4E-02 |
|
group | 0.010 | None | 1.000 | 1 | 2 | 2007 | 2007 | ||||||||
|
homeostatic iron regulator | 0.436 | 0.846 | 2.6E-08 |
|
group | 0.010 | None | < 0.001 | 1 | 2 | 2005 | 2005 | ||||||||
|
toll like receptor 4 | 0.321 | 0.962 | 4.6E-09 |
|
group | 0.010 | None | 1.000 | 1 | 2 | 2018 | 2018 | ||||||||
|
mutL homolog 1 | 0.399 | 0.808 | 3.4E-05 |
|
group | 0.100 | None | 0.886 | 35 | 1 | 1994 | 2018 |