Source: ALL

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 4854
Gene Symbol: NOTCH3
NOTCH3 		notch receptor 3 0.435 0.808 0.41
CUI: C0338656
Disease: Impaired cognition
Impaired cognition 		disease 0.400 strong 1.000 12 1 2007 2019
Entrez Id: 5654
Gene Symbol: HTRA1
HTRA1 		HtrA serine peptidase 1 0.532 0.692 4.9E-04
CUI: C0338656
Disease: Impaired cognition
Impaired cognition 		disease 0.410 strong 1.000 2 1 2014 2015
Entrez Id: 79152
Gene Symbol: FA2H
FA2H 		fatty acid 2-hydroxylase 0.573 0.654 0.15
CUI: C0338656
Disease: Impaired cognition
Impaired cognition 		disease 0.310 strong 1.000 2 0 2013 2019
Entrez Id: 1282
Gene Symbol: COL4A1
COL4A1 		collagen type IV alpha 1 chain 0.484 0.731 1.00
CUI: C0338656
Disease: Impaired cognition
Impaired cognition 		disease 0.300 strong 1.000 1 0 2007 2007
Entrez Id: 348
Gene Symbol: APOE
APOE 		apolipoprotein E 0.338 0.962 1.9E-03
CUI: C0338656
Disease: Impaired cognition
Impaired cognition 		disease 0.100 None 0.942 481 4 1995 2020
Entrez Id: 351
Gene Symbol: APP
APP 		amyloid beta precursor protein 0.422 0.846 4.7E-02
CUI: C0338656
Disease: Impaired cognition
Impaired cognition 		disease 0.600 None 0.980 202 11 1993 2020
Entrez Id: 627
Gene Symbol: BDNF
BDNF 		brain derived neurotrophic factor 0.345 0.923 0.66
CUI: C0338656
Disease: Impaired cognition
Impaired cognition 		disease 0.200 None 0.989 181 5 2006 2020
Entrez Id: 4137
Gene Symbol: MAPT
MAPT 		microtubule associated protein tau 0.446 0.923 6.0E-03
CUI: C0338656
Disease: Impaired cognition
Impaired cognition 		disease 0.100 None 0.985 67 4 2002 2020
Entrez Id: 43
Gene Symbol: ACHE
ACHE 		acetylcholinesterase (Cartwright blood group) 0.445 0.885 1.00
CUI: C0338656
Disease: Impaired cognition
Impaired cognition 		disease 0.100 None 0.951 41 0 2002 2020
Entrez Id: 1437
Gene Symbol: CSF2
CSF2 		colony stimulating factor 2 0.330 0.962 0.83
CUI: C0338656
Disease: Impaired cognition
Impaired cognition 		disease 0.100 None 0.923 39 0 2010 2020
Entrez Id: 3918
Gene Symbol: LAMC2
LAMC2 		laminin subunit gamma 2 0.389 0.923 2.9E-12
CUI: C0338656
Disease: Impaired cognition
Impaired cognition 		disease 0.100 None 0.923 39 0 2010 2020
Entrez Id: 3569
Gene Symbol: IL6
IL6 		interleukin 6 0.248 0.962 0.32
CUI: C0338656
Disease: Impaired cognition
Impaired cognition 		disease 0.100 None 0.919 37 1 2003 2020
Entrez Id: 6622
Gene Symbol: SNCA
SNCA 		synuclein alpha 0.427 0.885 0.88
CUI: C0338656
Disease: Impaired cognition
Impaired cognition 		disease 0.100 None 0.973 37 5 2000 2019
Entrez Id: 5663
Gene Symbol: PSEN1
PSEN1 		presenilin 1 0.469 0.846 0.97
CUI: C0338656
Disease: Impaired cognition
Impaired cognition 		disease 0.100 None 1.000 33 6 1998 2019
Entrez Id: 2332
Gene Symbol: FMR1
FMR1 		FMRP translational regulator 1 0.473 0.769 0.65
CUI: C0338656
Disease: Impaired cognition
Impaired cognition 		disease 0.100 None 0.969 32 0 1996 2020
Entrez Id: 7124
Gene Symbol: TNF
TNF 		tumor necrosis factor 0.231 0.962 0.80
CUI: C0338656
Disease: Impaired cognition
Impaired cognition 		disease 0.100 None 0.969 32 1 2001 2020
Entrez Id: 1312
Gene Symbol: COMT
COMT 		catechol-O-methyltransferase 0.400 0.923 1.1E-06
CUI: C0338656
Disease: Impaired cognition
Impaired cognition 		disease 0.100 None 0.935 31 3 2005 2020
Entrez Id: 1401
Gene Symbol: CRP
CRP 		C-reactive protein 0.299 0.962 3.7E-03
CUI: C0338656
Disease: Impaired cognition
Impaired cognition 		disease 0.100 None 1.000 29 0 2005 2019
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2 		nuclear factor, erythroid 2 like 2 0.357 0.885 3.6E-03
CUI: C0338656
Disease: Impaired cognition
Impaired cognition 		disease 0.100 None 1.000 29 1 2011 2020
Entrez Id: 23621
Gene Symbol: BACE1
BACE1 		beta-secretase 1 0.559 0.769 0.88
CUI: C0338656
Disease: Impaired cognition
Impaired cognition 		disease 0.300 None 0.963 27 0 2006 2020
Entrez Id: 590
Gene Symbol: BCHE
BCHE 		butyrylcholinesterase 0.447 0.923 1.1E-13
CUI: C0338656
Disease: Impaired cognition
Impaired cognition 		disease 0.100 None 0.962 26 2 2003 2019
Entrez Id: 1636
Gene Symbol: ACE
ACE 		angiotensin I converting enzyme 0.328 0.923 1.0E-37
CUI: C0338656
Disease: Impaired cognition
Impaired cognition 		disease 0.100 None 0.920 25 1 1996 2019
Entrez Id: 2551
Gene Symbol: GABPA
GABPA 		GA binding protein transcription factor subunit alpha 0.379 0.885 1.00
CUI: C0338656
Disease: Impaired cognition
Impaired cognition 		disease 0.100 None 1.000 24 0 2011 2020
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1 		sirtuin 1 0.378 0.885 8.7E-02
CUI: C0338656
Disease: Impaired cognition
Impaired cognition 		disease 0.100 None 1.000 23 0 2014 2019
Entrez Id: 345643
Gene Symbol: MCIDAS
MCIDAS 		multiciliate differentiation and DNA synthesis associated cell cycle protein 0.566 0.769 1.3E-02
CUI: C0338656
Disease: Impaired cognition
Impaired cognition 		disease 0.100 None 0.957 23 0 2009 2019