| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
von Hippel-Lindau tumor suppressor | 0.443 | 0.846 | 8.0E-02 |
|
disease | 0.700 | strong | 0.970 | 236 | 15 | 1989 | 2019 | ||||||||
|
vascular endothelial growth factor A | 0.266 | 0.923 | 2.4E-05 |
|
disease | 0.100 | None | 0.973 | 185 | 6 | 1994 | 2020 | ||||||||
|
transcription factor binding to IGHM enhancer 3 | 0.542 | 0.654 | 0.98 |
|
disease | 0.500 | None | 0.983 | 120 | 0 | 1996 | 2020 | ||||||||
|
tumor protein p53 | 0.236 | 0.962 | 0.53 |
|
disease | 0.500 | None | 0.900 | 90 | 31 | 1991 | 2019 | ||||||||
|
La ribonucleoprotein 6, translational regulator | 0.631 | 0.500 | 0.67 |
|
disease | 0.100 | None | 0.975 | 80 | 0 | 1992 | 2019 | ||||||||
|
hypoxia inducible factor 1 subunit alpha | 0.327 | 0.923 | 0.98 |
|
disease | 0.100 | None | 1.000 | 70 | 3 | 2000 | 2019 | ||||||||
|
CD274 molecule | 0.324 | 0.923 | 1.9E-02 |
|
disease | 0.100 | None | 0.968 | 62 | 0 | 2007 | 2020 | ||||||||
|
mechanistic target of rapamycin kinase | 0.343 | 0.885 | 1.00 |
|
disease | 0.500 | None | 0.983 | 58 | 8 | 2004 | 2020 | ||||||||
|
interleukin 2 | 0.336 | 0.885 | 0.48 |
|
disease | 0.100 | None | 1.000 | 52 | 0 | 1990 | 2019 | ||||||||
|
carbonic anhydrase 9 | 0.483 | 0.731 | 1.3E-09 |
|
disease | 0.100 | None | 1.000 | 51 | 0 | 1988 | 2020 | ||||||||
|
fumarate hydratase | 0.489 | 0.846 | 8.8E-02 |
|
disease | 0.200 | None | 0.960 | 50 | 0 | 2002 | 2020 | ||||||||
|
MET proto-oncogene, receptor tyrosine kinase | 0.380 | 0.846 | 0.97 |
|
disease | 0.400 | None | 0.953 | 43 | 9 | 1996 | 2020 | ||||||||
|
epidermal growth factor receptor | 0.295 | 0.885 | 0.37 |
|
disease | 0.100 | None | 0.952 | 42 | 0 | 1988 | 2019 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | 0.292 | 0.923 | 1.00 |
|
disease | 0.500 | None | 1.000 | 40 | 7 | 2006 | 2019 | ||||||||
|
endothelial PAS domain protein 1 | 0.454 | 0.731 | 0.60 |
|
disease | 0.700 | None | 0.974 | 38 | 20 | 2001 | 2019 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma | 0.320 | 0.885 | 1.4E-06 |
|
disease | 0.100 | None | 1.000 | 38 | 0 | 2006 | 2019 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta | 0.322 | 0.885 | 1.00 |
|
disease | 0.100 | None | 1.000 | 36 | 0 | 2006 | 2019 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta | 0.319 | 0.885 | 1.00 |
|
disease | 0.100 | None | 1.000 | 36 | 0 | 2006 | 2019 | ||||||||
|
phosphatase and tensin homolog | 0.305 | 0.923 | 0.26 |
|
disease | 0.700 | None | 1.000 | 35 | 3 | 1998 | 2020 | ||||||||
|
transcription factor EB | 0.527 | 0.731 | 0.90 |
|
disease | 0.100 | None | 1.000 | 35 | 0 | 2003 | 2020 | ||||||||
|
BCL2 apoptosis regulator | 0.291 | 0.885 | 0.56 |
|
disease | 0.100 | None | 0.970 | 33 | 0 | 1996 | 2019 | ||||||||
|
BRCA1 associated protein 1 | 0.454 | 0.731 | 0.99 |
|
disease | 0.500 | None | 0.967 | 30 | 2 | 2011 | 2019 | ||||||||
|
interleukin 6 | 0.248 | 0.962 | 0.32 |
|
disease | 0.400 | None | 0.966 | 29 | 0 | 1989 | 2019 | ||||||||
|
tumor necrosis factor | 0.231 | 0.962 | 0.80 |
|
disease | 0.100 | None | 1.000 | 28 | 0 | 1992 | 2019 | ||||||||
|
kinase insert domain receptor | 0.378 | 0.885 | 1.00 |
|
disease | 0.100 | None | 0.963 | 27 | 0 | 2001 | 2019 |