×
Entrez Id:
5743
Gene Symbol:
PTGS2
PTGS2
Colorectal Neoplasms
0.400
AlteredExpression
LHGDN
Modulation of cyclooxygenase-2 expression by APC in HT-29 human colorectal carcinoma cells.
12664576
2002
×
Entrez Id:
5743
Gene Symbol:
PTGS2
PTGS2
Colorectal Neoplasms
0.400
AlteredExpression
LHGDN
The MEK/ERK pathway mediates COX-2-selective NSAID-induced apoptosis and induced COX-2 protein expression in colorectal carcinoma cells.
11992399
2002
×
Entrez Id:
5743
Gene Symbol:
PTGS2
PTGS2
Colorectal Neoplasms
0.400
AlteredExpression
LHGDN
Cyclooxygenase-2 expression correlates with uPAR levels and is responsible for poor prognosis of colorectal cancer.
12405290
2002
×
Entrez Id:
5743
Gene Symbol:
PTGS2
PTGS2
Colorectal Neoplasms
0.400
AlteredExpression
LHGDN
[Relationship between carcinoembryonic antigen and cyclooxygenase 2 expression and colorectal cancer].
12600292
2003
×
Entrez Id:
5743
Gene Symbol:
PTGS2
PTGS2
Colorectal Neoplasms
0.400
AlteredExpression
LHGDN
Upregulation of cyclooxygenase-2 is accompanied by increased expression of nuclear factor-kappa B and I kappa B kinase-alpha in human colorectal cancer epithelial cells.
12771929
2003
×
Entrez Id:
5743
Gene Symbol:
PTGS2
PTGS2
Colorectal Neoplasms
0.400
Biomarker
LHGDN
Cyclooxygenase-2 expression and angiogenesis in colorectal cancer.
12800231
2003
×
Entrez Id:
5743
Gene Symbol:
PTGS2
PTGS2
Colorectal Neoplasms
0.400
AlteredExpression
LHGDN
Expression of cyclooxygenase-2 parallels expression of interleukin-1beta, interleukin-6 and NF-kappaB in human colorectal cancer.
12727794
2003
×
Entrez Id:
5743
Gene Symbol:
PTGS2
PTGS2
Colorectal Neoplasms
0.400
Biomarker
LHGDN
Cyclooxygenase-2 expression in primary human colorectal cancers and bone marrow micrometastases.
15248379
2004
×
Entrez Id:
5743
Gene Symbol:
PTGS2
PTGS2
Colorectal Neoplasms
0.400
AlteredExpression
LHGDN
RNA profiling of cyclooxygenases 1 and 2 in colorectal cancer.
15328521
2004
×
Entrez Id:
5743
Gene Symbol:
PTGS2
PTGS2
Colorectal Neoplasms
0.400
AlteredExpression
LHGDN
Cyclooxygenase-2 activation mediates the proangiogenic effect of nitric oxide in colorectal cancer.
15102673
2004
×
Entrez Id:
5743
Gene Symbol:
PTGS2
PTGS2
Colorectal Neoplasms
0.400
Biomarker
LHGDN
COX-2 expression and tumor angiogenesis in colorectal cancer.
15285012
2004
×
Entrez Id:
5743
Gene Symbol:
PTGS2
PTGS2
Colorectal Neoplasms
0.400
GeneticVariation
LHGDN
Polymorphisms in prostaglandin synthase 2/cyclooxygenase 2 (PTGS2/COX2) and risk of colorectal cancer.
15173859
2004
×
Entrez Id:
5743
Gene Symbol:
PTGS2
PTGS2
Colorectal Neoplasms
0.400
Biomarker
LHGDN
Lysophosphatidic acid transactivates both c-Met and epidermal growth factor receptor, and induces cyclooxygenase-2 expression in human colon cancer LoVo cells.
16237757
2005
×
Entrez Id:
5743
Gene Symbol:
PTGS2
PTGS2
Colorectal Neoplasms
0.400
GeneticVariation
LHGDN
Analysis of K-ras mutations and expression of cyclooxygenase-2 and gastrin protein in laterally spreading tumors.
16174078
2005
×
Entrez Id:
5743
Gene Symbol:
PTGS2
PTGS2
Colorectal Neoplasms
0.400
AlteredExpression
LHGDN
Coexpression of VEGF-C and Cox-2 in human colorectal cancer and its association with lymph node metastasis.
16474989
2006
×
Entrez Id:
5743
Gene Symbol:
PTGS2
PTGS2
Colorectal Neoplasms
0.400
Biomarker
LHGDN
Combined analysis of COX-2 and p53 expressions reveals synergistic inverse correlations with microsatellite instability and CpG island methylator phenotype in colorectal cancer.
16820091
2006
×
Entrez Id:
5743
Gene Symbol:
PTGS2
PTGS2
Colorectal Neoplasms
0.400
GeneticVariation
LHGDN
Associations of functional polymorphisms in cyclooxygenase-2 and platelet 12-lipoxygenase with risk of occurrence and advanced disease status of colorectal cancer.
17151091
2007
×
Entrez Id:
5743
Gene Symbol:
PTGS2
PTGS2
Colorectal Neoplasms
0.400
AlteredExpression
LHGDN
Expression of cyclooxygenase-2 and its relationship to p53 accumulation in colorectal cancers.
17594159
2007
×
Entrez Id:
5743
Gene Symbol:
PTGS2
PTGS2
Colorectal Neoplasms
0.400
AlteredExpression
LHGDN
An upstream CRE-E-box element is essential for gastrin-dependent activation of the cyclooxygenase-2 gene in human colon cancer cells.
17604853
2007
×
Entrez Id:
5743
Gene Symbol:
PTGS2
PTGS2
Colorectal Neoplasms
0.400
AlteredExpression
LHGDN
Detection of colorectal cancer cells from feces using quantitative real-time RT-PCR for colorectal cancer diagnosis.
19016757
2008
×
Entrez Id:
5743
Gene Symbol:
PTGS2
PTGS2
Colorectal Neoplasms
0.400
Biomarker
LHGDN
Proline oxidase, a p53-induced gene, targets COX-2/PGE2 signaling to induce apoptosis and inhibit tumor growth in colorectal cancers.
18794809
2008
×
Entrez Id:
5743
Gene Symbol:
PTGS2
PTGS2
Colorectal Neoplasms
0.400
GeneticVariation
LHGDN
Polymorphisms in cyclooxygenase-2 and epidermal growth factor receptor are associated with progression-free survival independent of K-ras in metastatic colorectal cancer patients treated with single-agent cetuximab.
19047118
2008