| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
tumor necrosis factor | 0.231 | 0.962 | 0.80 |
|
disease | 0.100 | None | 0.917 | 12 | 0 | 2002 | 2017 | ||||||||
|
interleukin 6 | 0.248 | 0.962 | 0.32 |
|
disease | 0.030 | None | 1.000 | 3 | 0 | 2008 | 2017 | ||||||||
|
interleukin 1 beta | 0.276 | 0.962 | 0.13 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2002 | 2002 | ||||||||
|
interleukin 10 | 0.281 | 0.923 | 5.9E-03 |
|
disease | 0.020 | None | 1.000 | 2 | 0 | 2008 | 2015 | ||||||||
|
transforming growth factor beta 1 | 0.287 | 0.962 | 3.7E-02 |
|
disease | 0.020 | None | 0.500 | 2 | 0 | 2003 | 2007 | ||||||||
|
interferon gamma | 0.288 | 0.962 | 0.47 |
|
disease | 0.020 | None | 1.000 | 2 | 0 | 2004 | 2008 | ||||||||
|
BCL2 apoptosis regulator | 0.291 | 0.885 | 0.56 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2017 | 2017 | ||||||||
|
C-reactive protein | 0.299 | 0.962 | 3.7E-03 |
|
disease | 0.020 | None | 1.000 | 2 | 0 | 2017 | 2019 | ||||||||
|
cyclin dependent kinase inhibitor 2A | 0.300 | 0.885 | 0.39 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2004 | 2004 | ||||||||
|
matrix metallopeptidase 9 | 0.305 | 0.923 | 1.9E-17 |
|
disease | 0.010 | None | < 0.001 | 1 | 2 | 2015 | 2015 | ||||||||
|
C-X-C motif chemokine ligand 8 | 0.310 | 0.962 | 2.7E-04 |
|
disease | 0.030 | None | 1.000 | 3 | 0 | 1993 | 2017 | ||||||||
|
C-C motif chemokine ligand 2 | 0.321 | 0.962 | 0.61 |
|
disease | 0.020 | None | 1.000 | 2 | 0 | 2015 | 2016 | ||||||||
|
toll like receptor 4 | 0.321 | 0.962 | 4.6E-09 |
|
disease | 0.010 | None | 1.000 | 1 | 1 | 2016 | 2016 | ||||||||
|
interleukin 17A | 0.324 | 0.923 | 4.3E-02 |
|
disease | 0.060 | None | 1.000 | 6 | 0 | 2012 | 2017 | ||||||||
|
mitogen-activated protein kinase 1 | 0.330 | 0.923 | 1.00 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2004 | 2004 | ||||||||
|
major histocompatibility complex, class II, DR beta 1 | 0.333 | 0.923 | 1.1E-03 |
|
disease | 0.070 | None | 0.857 | 7 | 0 | 1998 | 2020 | ||||||||
|
methylenetetrahydrofolate reductase | 0.337 | 0.885 | 3.2E-10 |
|
disease | 0.010 | None | 1.000 | 1 | 1 | 2012 | 2012 | ||||||||
|
apolipoprotein E | 0.338 | 0.962 | 1.9E-03 |
|
disease | 0.020 | None | 1.000 | 2 | 0 | 1997 | 2003 | ||||||||
|
cyclin D1 | 0.344 | 0.923 | 0.89 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2017 | 2017 | ||||||||
|
brain derived neurotrophic factor | 0.345 | 0.923 | 0.66 |
|
disease | 0.010 | None | 1.000 | 1 | 2 | 2014 | 2014 | ||||||||
|
caspase 3 | 0.351 | 0.923 | 0.10 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2017 | 2017 | ||||||||
|
vitamin D receptor | 0.352 | 0.885 | 1.7E-05 |
|
disease | 0.030 | None | 1.000 | 3 | 0 | 2002 | 2012 | ||||||||
|
nuclear factor, erythroid 2 like 2 | 0.357 | 0.885 | 3.6E-03 |
|
disease | 0.030 | None | 1.000 | 3 | 0 | 2017 | 2020 | ||||||||
|
epidermal growth factor | 0.357 | 0.923 | 8.5E-17 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2003 | 2003 | ||||||||
|
peroxisome proliferator activated receptor gamma | 0.358 | 0.885 | 2.9E-02 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2020 | 2020 |