Source: CURATED

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
KRAS proto-oncogene, GTPase 0.320 0.923 7.9E-04
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
group 0.600 None 0.974 33 0 1991 2019
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
epidermal growth factor receptor 0.295 0.885 0.37
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
group 0.600 None 0.984 7 0 1994 2019
Entrez Id: 1548
Gene Symbol: CYP2A6
CYP2A6
cytochrome P450 family 2 subfamily A member 6 0.556 0.731 5.4E-09
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
group 0.340 None 1.000 6 0 1999 2015
Entrez Id: 7157
Gene Symbol: TP53
TP53
tumor protein p53 0.236 0.962 0.53
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
group 0.800 None 0.974 5 0 1990 2019
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
HRas proto-oncogene, GTPase 0.378 0.885 8.0E-02
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
group 0.380 None 1.000 5 0 1986 2010
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
cyclin dependent kinase inhibitor 2A 0.300 0.885 0.39
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
group 0.800 None 1.000 4 0 1997 2019
Entrez Id: 207
Gene Symbol: AKT1
AKT1
AKT serine/threonine kinase 1 0.311 0.962 0.98
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
group 0.500 None 1.000 3 0 2003 2019
Entrez Id: 81037
Gene Symbol: CLPTM1L
CLPTM1L
CLPTM1 like 0.551 0.654 4.4E-05
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
group 0.330 None 1.000 3 0 2008 2014
Entrez Id: 3558
Gene Symbol: IL2
IL2
interleukin 2 0.336 0.885 0.48
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
group 0.320 None 1.000 3 0 1994 2009
Entrez Id: 1027
Gene Symbol: CDKN1B
CDKN1B
cyclin dependent kinase inhibitor 1B 0.409 0.769 0.62
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
group 0.320 None 1.000 3 0 1998 2010
Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
glutathione S-transferase mu 1 0.380 0.923 2.1E-03
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
group 0.400 None 1.000 3 0 1994 2012
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
transforming growth factor beta 1 0.287 0.962 3.7E-02
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
group 0.380 None 1.000 3 0 2000 2019
Entrez Id: 332
Gene Symbol: BIRC5
BIRC5
baculoviral IAP repeat containing 5 0.495 0.731 5.6E-02
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
group 0.390 None 1.000 2 0 2004 2009
Entrez Id: 7508
Gene Symbol: XPC
XPC
XPC complex subunit, DNA damage recognition and repair factor 0.504 0.808 3.7E-11
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
group 0.350 None 1.000 2 0 2005 2013
Entrez Id: 3726
Gene Symbol: JUNB
JUNB
JunB proto-oncogene, AP-1 transcription factor subunit 0.467 0.769 0.86
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
group 0.300 None 1.000 2 0 2006 2017
Entrez Id: 1571
Gene Symbol: CYP2E1
CYP2E1
cytochrome P450 family 2 subfamily E member 1 0.459 0.885 8.1E-09
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
group 0.330 None 1.000 2 0 1991 2009
Entrez Id: 7015
Gene Symbol: TERT
TERT
telomerase reverse transcriptase 0.374 0.846 0.99
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
group 0.400 None 1.000 2 0 2000 2017
Entrez Id: 5595
Gene Symbol: MAPK3
MAPK3
mitogen-activated protein kinase 3 0.379 0.885 3.7E-02
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
group 0.340 None 1.000 2 0 2002 2018
Entrez Id: 6696
Gene Symbol: SPP1
SPP1
secreted phosphoprotein 1 0.353 0.885 2.1E-06
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
group 0.360 None 1.000 2 0 1996 2012
Entrez Id: 2305
Gene Symbol: FOXM1
FOXM1
forkhead box M1 0.441 0.769 7.4E-04
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
group 0.370 None 1.000 2 0 2006 2019
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
estrogen receptor 1 0.324 0.962 1.00
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
group 0.380 None 1.000 2 0 2002 2019
Entrez Id: 348
Gene Symbol: APOE
APOE
apolipoprotein E 0.338 0.962 1.9E-03
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
group 0.320 None 1.000 2 0 2008 2019
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
phosphatase and tensin homolog 0.305 0.923 0.26
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
group 0.700 None 1.000 2 0 1998 2017
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
interleukin 1 beta 0.276 0.962 0.13
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
group 0.330 None 1.000 2 0 2004 2017
Entrez Id: 2
Gene Symbol: A2M
A2M
alpha-2-macroglobulin 0.529 0.769 4.5E-11
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
group 0.300 None 1.000 2 0 2007 2009