| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
tumor necrosis factor | 0.231 | 0.962 | 0.80 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2016 | 2016 | ||||||||
|
tumor protein p53 | 0.236 | 0.962 | 0.53 |
|
disease | 0.800 | strong | 0.960 | 50 | 26 | 1992 | 2017 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | 0.292 | 0.923 | 1.00 |
|
disease | 0.100 | None | 1.000 | 1 | 3 | 2016 | 2016 | ||||||||
|
epidermal growth factor receptor | 0.295 | 0.885 | 0.37 |
|
disease | 0.340 | None | 1.000 | 4 | 0 | 2009 | 2013 | ||||||||
|
cyclin dependent kinase inhibitor 2A | 0.300 | 0.885 | 0.39 |
|
disease | 0.310 | None | 1.000 | 2 | 0 | 2012 | 2014 | ||||||||
|
catenin beta 1 | 0.303 | 0.885 | 1.00 |
|
disease | 0.500 | None | 1.000 | 20 | 6 | 2005 | 2020 | ||||||||
|
C-X-C motif chemokine ligand 8 | 0.310 | 0.962 | 2.7E-04 |
|
disease | 0.020 | None | 1.000 | 2 | 0 | 2007 | 2020 | ||||||||
|
AKT serine/threonine kinase 1 | 0.311 | 0.962 | 0.98 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2012 | 2012 | ||||||||
|
albumin | 0.317 | 0.962 | 0.64 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2012 | 2012 | ||||||||
|
insulin like growth factor 1 | 0.318 | 0.885 | 0.27 |
|
disease | 0.080 | None | 1.000 | 8 | 0 | 1996 | 2019 | ||||||||
|
B-Raf proto-oncogene, serine/threonine kinase | 0.319 | 0.846 | 1.00 |
|
disease | 0.420 | None | 1.000 | 4 | 2 | 2009 | 2016 | ||||||||
|
KRAS proto-oncogene, GTPase | 0.320 | 0.923 | 7.9E-04 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2015 | 2015 | ||||||||
|
signal transducer and activator of transcription 3 | 0.320 | 0.923 | 1.00 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2019 | 2019 | ||||||||
|
estrogen receptor 1 | 0.324 | 0.962 | 1.00 |
|
disease | 0.060 | None | 1.000 | 6 | 0 | 2005 | 2017 | ||||||||
|
CD274 molecule | 0.324 | 0.923 | 1.9E-02 |
|
disease | 0.020 | None | 0.500 | 2 | 0 | 2018 | 2019 | ||||||||
|
mitogen-activated protein kinase 1 | 0.330 | 0.923 | 1.00 |
|
disease | 0.030 | None | 1.000 | 3 | 0 | 2009 | 2018 | ||||||||
|
major histocompatibility complex, class II, DR beta 1 | 0.333 | 0.923 | 1.1E-03 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2005 | 2005 | ||||||||
|
mechanistic target of rapamycin kinase | 0.343 | 0.885 | 1.00 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2020 | 2020 | ||||||||
|
ATP binding cassette subfamily B member 1 | 0.344 | 0.885 | 1.3E-05 |
|
disease | 0.330 | None | 1.000 | 4 | 0 | 1991 | 2019 | ||||||||
|
cyclin D1 | 0.344 | 0.923 | 0.89 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2017 | 2017 | ||||||||
|
leptin | 0.349 | 0.846 | 0.46 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 1999 | 1999 | ||||||||
|
androgen receptor | 0.351 | 0.846 | 0.99 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2020 | 2020 | ||||||||
|
caspase 3 | 0.351 | 0.923 | 0.10 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2017 | 2017 | ||||||||
|
secreted phosphoprotein 1 | 0.353 | 0.885 | 2.1E-06 |
|
disease | 0.010 | None | < 0.001 | 1 | 0 | 2009 | 2009 | ||||||||
|
proopiomelanocortin | 0.356 | 0.846 | 1.2E-04 |
|
disease | 0.060 | None | 1.000 | 6 | 0 | 2008 | 2019 |