Source: ALL

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53 		tumor protein p53 0.236 0.962 0.53
CUI: C4528668
Disease: Acute myeloid leukaemia refractory
Acute myeloid leukaemia refractory 		disease 0.010 None 1.000 1 0 2017 2017
Entrez Id: 596
Gene Symbol: BCL2
BCL2 		BCL2 apoptosis regulator 0.291 0.885 0.56
CUI: C4528668
Disease: Acute myeloid leukaemia refractory
Acute myeloid leukaemia refractory 		disease 0.030 None 1.000 3 0 2017 2019
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha 0.292 0.923 1.00
CUI: C4528668
Disease: Acute myeloid leukaemia refractory
Acute myeloid leukaemia refractory 		disease 0.010 None 1.000 1 0 2015 2015
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		phosphatase and tensin homolog 0.305 0.923 0.26
CUI: C4528668
Disease: Acute myeloid leukaemia refractory
Acute myeloid leukaemia refractory 		disease 0.010 None 1.000 1 0 2019 2019
Entrez Id: 207
Gene Symbol: AKT1
AKT1 		AKT serine/threonine kinase 1 0.311 0.962 0.98
CUI: C4528668
Disease: Acute myeloid leukaemia refractory
Acute myeloid leukaemia refractory 		disease 0.010 None 1.000 1 0 2016 2016
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		KRAS proto-oncogene, GTPase 0.320 0.923 7.9E-04
CUI: C4528668
Disease: Acute myeloid leukaemia refractory
Acute myeloid leukaemia refractory 		disease 0.010 None 1.000 1 0 2016 2016
Entrez Id: 1437
Gene Symbol: CSF2
CSF2 		colony stimulating factor 2 0.330 0.962 0.83
CUI: C4528668
Disease: Acute myeloid leukaemia refractory
Acute myeloid leukaemia refractory 		disease 0.010 None 1.000 1 0 2001 2001
Entrez Id: 3558
Gene Symbol: IL2
IL2 		interleukin 2 0.336 0.885 0.48
CUI: C4528668
Disease: Acute myeloid leukaemia refractory
Acute myeloid leukaemia refractory 		disease 0.010 None 1.000 1 0 2019 2019
Entrez Id: 2475
Gene Symbol: MTOR
MTOR 		mechanistic target of rapamycin kinase 0.343 0.885 1.00
CUI: C4528668
Disease: Acute myeloid leukaemia refractory
Acute myeloid leukaemia refractory 		disease 0.010 None 1.000 1 0 2015 2015
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1 		ATP binding cassette subfamily B member 1 0.344 0.885 1.3E-05
CUI: C4528668
Disease: Acute myeloid leukaemia refractory
Acute myeloid leukaemia refractory 		disease 0.020 None 1.000 2 0 2000 2001
Entrez Id: 4193
Gene Symbol: MDM2
MDM2 		MDM2 proto-oncogene 0.362 0.846 1.00
CUI: C4528668
Disease: Acute myeloid leukaemia refractory
Acute myeloid leukaemia refractory 		disease 0.040 None 1.000 4 0 2018 2019
Entrez Id: 947
Gene Symbol: CD34
CD34 		CD34 molecule 0.368 0.808 5.0E-06
CUI: C4528668
Disease: Acute myeloid leukaemia refractory
Acute myeloid leukaemia refractory 		disease 0.010 None 1.000 1 0 2011 2011
Entrez Id: 1440
Gene Symbol: CSF3
CSF3 		colony stimulating factor 3 0.377 0.885 0.38
CUI: C4528668
Disease: Acute myeloid leukaemia refractory
Acute myeloid leukaemia refractory 		disease 0.100 None 1.000 13 0 2014 2020
Entrez Id: 5781
Gene Symbol: PTPN11
PTPN11 		protein tyrosine phosphatase non-receptor type 11 0.385 0.923 1.00
CUI: C4528668
Disease: Acute myeloid leukaemia refractory
Acute myeloid leukaemia refractory 		disease 0.010 None 1.000 1 0 2016 2016
Entrez Id: 4893
Gene Symbol: NRAS
NRAS 		NRAS proto-oncogene, GTPase 0.390 0.808 0.49
CUI: C4528668
Disease: Acute myeloid leukaemia refractory
Acute myeloid leukaemia refractory 		disease 0.010 None 1.000 1 0 2016 2016
Entrez Id: 4790
Gene Symbol: NFKB1
NFKB1 		nuclear factor kappa B subunit 1 0.396 0.923 1.00
CUI: C4528668
Disease: Acute myeloid leukaemia refractory
Acute myeloid leukaemia refractory 		disease 0.010 None 1.000 1 0 2016 2016
Entrez Id: 23158
Gene Symbol: TBC1D9
TBC1D9 		TBC1 domain family member 9 0.399 0.846 2.8E-05
CUI: C4528668
Disease: Acute myeloid leukaemia refractory
Acute myeloid leukaemia refractory 		disease 0.020 None 1.000 2 0 2000 2001
Entrez Id: 5573
Gene Symbol: PRKAR1A
PRKAR1A 		protein kinase cAMP-dependent type I regulatory subunit alpha 0.401 0.846 1.00
CUI: C4528668
Disease: Acute myeloid leukaemia refractory
Acute myeloid leukaemia refractory 		disease 0.020 None 1.000 2 0 2018 2018
Entrez Id: 846
Gene Symbol: CASR
CASR 		calcium sensing receptor 0.410 0.846 4.7E-02
CUI: C4528668
Disease: Acute myeloid leukaemia refractory
Acute myeloid leukaemia refractory 		disease 0.020 None 1.000 2 0 2018 2018
Entrez Id: 5156
Gene Symbol: PDGFRA
PDGFRA 		platelet derived growth factor receptor alpha 0.415 0.808 1.00
CUI: C4528668
Disease: Acute myeloid leukaemia refractory
Acute myeloid leukaemia refractory 		disease 0.010 None 1.000 1 0 2014 2014
Entrez Id: 5609
Gene Symbol: MAP2K7
MAP2K7 		mitogen-activated protein kinase kinase 7 0.419 0.808 1.00
CUI: C4528668
Disease: Acute myeloid leukaemia refractory
Acute myeloid leukaemia refractory 		disease 0.010 None 1.000 1 0 2019 2019
Entrez Id: 9429
Gene Symbol: ABCG2
ABCG2 		ATP binding cassette subfamily G member 2 (Junior blood group) 0.419 0.885 2.1E-32
CUI: C4528668
Disease: Acute myeloid leukaemia refractory
Acute myeloid leukaemia refractory 		disease 0.010 None 1.000 1 0 2002 2002
Entrez Id: 3417
Gene Symbol: IDH1
IDH1 		isocitrate dehydrogenase (NADP(+)) 1 0.424 0.808 2.6E-12
CUI: C4528668
Disease: Acute myeloid leukaemia refractory
Acute myeloid leukaemia refractory 		disease 0.050 None 1.000 5 0 2015 2019
Entrez Id: 3418
Gene Symbol: IDH2
IDH2 		isocitrate dehydrogenase (NADP(+)) 2 0.434 0.808 0.88
CUI: C4528668
Disease: Acute myeloid leukaemia refractory
Acute myeloid leukaemia refractory 		disease 0.030 None 1.000 3 0 2018 2018
Entrez Id: 6687
Gene Symbol: SPG7
SPG7 		SPG7 matrix AAA peptidase subunit, paraplegin 0.436 0.885 2.0E-36
CUI: C4528668
Disease: Acute myeloid leukaemia refractory
Acute myeloid leukaemia refractory 		disease 0.020 None 1.000 2 0 2018 2018