×
Entrez Id:
1773
Gene Symbol:
DNASE1
DNASE1
Lupus Erythematosus, Systemic
0.900
Biomarker
MGD
Our findings suggest that lack or reduction of Dnase1 is a critical factor in the initiation of human SLE .
10835632
2000
×
Entrez Id:
2213
Gene Symbol:
FCGR2B
FCGR2B
Lupus Erythematosus, Systemic
0.900
Biomarker
MGD
A novel Akt3 mutation associated with enhanced kinase activity and seizure susceptibility in mice.
21159799
2011
×
Entrez Id:
2213
Gene Symbol:
FCGR2B
FCGR2B
Lupus Erythematosus, Systemic
0.900
Biomarker
MGD
Spontaneous autoimmune disease in Fc(gamma)RIIB-deficient mice results from strain-specific epistasis.
10981970
2000
×
Entrez Id:
5133
Gene Symbol:
PDCD1
PDCD1
Lupus Erythematosus, Systemic
0.800
Biomarker
MGD
Development of lupus -like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor.
10485649
1999
×
Entrez Id:
5133
Gene Symbol:
PDCD1
PDCD1
Lupus Erythematosus, Systemic
0.800
Biomarker
MGD
Differential effects of B and T lymphocyte attenuator and programmed death-1 on acceptance of partially versus fully MHC-mismatched cardiac allografts.
16237069
2005
×
Entrez Id:
5133
Gene Symbol:
PDCD1
PDCD1
Lupus Erythematosus, Systemic
0.800
Biomarker
MGD
Immunological studies on PD-1 deficient mice: implication of PD-1 as a negative regulator for B cell responses.
9796923
1998
×
Entrez Id:
64135
Gene Symbol:
IFIH1
IFIH1
Lupus Erythematosus, Systemic
0.700
Biomarker
MGD
We established a mutant mouse line bearing MDA5 mutation by ENU mutagenesis, which spontaneously developed lupus -like autoimmune symptoms without viral infection.
24530055
2014
×
Entrez Id:
720
Gene Symbol:
C4A
C4A
Lupus Erythematosus, Systemic
0.700
Biomarker
MGD
Complement C4 inhibits systemic autoimmunity through a mechanism independent of complement receptors CR1 and CR2.
11067882
2000
×
Entrez Id:
712
Gene Symbol:
C1QA
C1QA
Lupus Erythematosus, Systemic
0.670
Biomarker
MGD
Central role of complement in passive protection by human IgG1 and IgG2 anti-pneumococcal antibodies in mice.
12794146
2003
×
Entrez Id:
712
Gene Symbol:
C1QA
C1QA
Lupus Erythematosus, Systemic
0.670
Biomarker
MGD
Homozygous C1q deficiency causes glomerulonephritis associated with multiple apoptotic bodies.
9590289
1998
×
Entrez Id:
10125
Gene Symbol:
RASGRP1
RASGRP1
Lupus Erythematosus, Systemic
0.620
Biomarker
MGD
Autoimmunity as the consequence of a spontaneous mutation in Rasgrp1.
12932358
2003
×
Entrez Id:
721
Gene Symbol:
C4B
C4B
Lupus Erythematosus, Systemic
0.600
Biomarker
MGD
Complement C4 inhibits systemic autoimmunity through a mechanism independent of complement receptors CR1 and CR2.
11067882
2000
×
Entrez Id:
639
Gene Symbol:
PRDM1
PRDM1
Lupus Erythematosus, Systemic
0.550
Biomarker
MGD
×
Entrez Id:
50619
Gene Symbol:
DEF6
DEF6
Lupus Erythematosus, Systemic
0.520
Biomarker
MGD
Loss of IRF-4-binding protein leads to the spontaneous development of systemic autoimmunity.
16470246
2006
×
Entrez Id:
355
Gene Symbol:
FAS
FAS
Lupus Erythematosus, Systemic
0.400
Biomarker
MGD
Comparative influence of steroid hormones and immunosuppressive agents on autoimmune expression in lacrimal glands of a female mouse model of Sjögren's syndrome.
8163351
1994
×
Entrez Id:
355
Gene Symbol:
FAS
FAS
Lupus Erythematosus, Systemic
0.400
Biomarker
MGD
Dissociation of severe lupus-like disease from polyclonal B cell activation and IL 2 deficiency in C3H-lpr/lpr mice.
6610701
1984
×
Entrez Id:
355
Gene Symbol:
FAS
FAS
Lupus Erythematosus, Systemic
0.400
Biomarker
MGD
Spontaneous murine lupus-like syndromes. Clinical and immunopathological manifestations in several strains.
309911
1978
×
Entrez Id:
355
Gene Symbol:
FAS
FAS
Lupus Erythematosus, Systemic
0.400
Biomarker
MGD
Deficient interleukin 2 activity in MRL/Mp and C57BL/6J mice bearing the lpr gene.
6975351
1981
×
Entrez Id:
355
Gene Symbol:
FAS
FAS
Lupus Erythematosus, Systemic
0.400
Biomarker
MGD
Anti-DNA B cells in MRL/lpr mice show altered differentiation and editing pattern.
12486097
2002
×
Entrez Id:
355
Gene Symbol:
FAS
FAS
Lupus Erythematosus, Systemic
0.400
Biomarker
MGD
Transfer of Sjögren's syndrome-like autoimmune lesions into SCID mice and prevention of lesions by anti-CD4 and anti-T cell receptor antibody treatment.
7957574
1994
×
Entrez Id:
355
Gene Symbol:
FAS
FAS
Lupus Erythematosus, Systemic
0.400
Biomarker
MGD
Reduced cell-cell communication in a spontaneous murine model of autoimmune thyroid disease.
7628400
1995
×
Entrez Id:
355
Gene Symbol:
FAS
FAS
Lupus Erythematosus, Systemic
0.400
Biomarker
MGD
Splenic immunoglobulin-secreting cells and their regulation in autoimmune mice.
6444324
1980
×
Entrez Id:
355
Gene Symbol:
FAS
FAS
Lupus Erythematosus, Systemic
0.400
Biomarker
MGD
Phenotypic, functional, and molecular genetic comparisons of the abnormal lymphoid cells of C3H-lpr/lpr and C3H-gld/gld mice.
3009614
1986
×
Entrez Id:
355
Gene Symbol:
FAS
FAS
Lupus Erythematosus, Systemic
0.400
Biomarker
MGD
Distribution of lymphocytes identified by surface markers in murine strains with systemic lupus erythematosus-like syndromes.
762500
1979
×
Entrez Id:
9474
Gene Symbol:
ATG5
ATG5
Lupus Erythematosus, Systemic
0.390
Biomarker
MGD