DisGeNET - a database of gene-disease associations

Source: BEFREE

Disease: Major Depressive Disorder ×

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Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Gene

Gene Full Name

DSI _g

DPI _g

pLI

Disease

Type

Score _gda

EL_gda

EI _gda

N.PMIDs

N.SNPs _gda

First Ref.

LastRef.

Entrez Id:	1453
Gene Symbol:	CSNK1D

CSNK1D

casein kinase 1 delta

0.650

0.615

1.00

CUI:	C1269683
Disease:	Major Depressive Disorder

Major Depressive Disorder

disease

0.310

None

< 0.001

2012

Entrez Id:	5879
Gene Symbol:	RAC1

RAC1

Rac family small GTPase 1

0.429

0.962

0.76

CUI:	C1269683
Disease:	Major Depressive Disorder

Major Depressive Disorder

disease

0.010

None

< 0.001

2015

Entrez Id:	1431
Gene Symbol:	CS

citrate synthase

0.590

0.654

0.98

CUI:	C1269683
Disease:	Major Depressive Disorder

Major Depressive Disorder

disease

0.010

None

< 0.001

2019

Entrez Id:	8942
Gene Symbol:	KYNU

KYNU

kynureninase

0.617

0.692

4.2E-18

CUI:	C1269683
Disease:	Major Depressive Disorder

Major Depressive Disorder

disease

0.310

None

< 0.001

2012

Entrez Id:	4208
Gene Symbol:	MEF2C

MEF2C

myocyte enhancer factor 2C

0.517

0.769

1.7E-02

CUI:	C1269683
Disease:	Major Depressive Disorder

Major Depressive Disorder

disease

0.010

None

< 0.001

2018

Entrez Id:	266727
Gene Symbol:	MDGA1

MDGA1

MAM domain containing glycosylphosphatidylinositol anchor 1

0.821

0.154

0.98

CUI:	C1269683
Disease:	Major Depressive Disorder

Major Depressive Disorder

disease

0.310

None

< 0.001

2011

Entrez Id:	54584
Gene Symbol:	GNB1L

GNB1L

G protein subunit beta 1 like

0.743

0.346

4.7E-05

CUI:	C1269683
Disease:	Major Depressive Disorder

Major Depressive Disorder

disease

0.310

None

< 0.001

2011

Entrez Id:	883
Gene Symbol:	KYAT1

KYAT1

kynurenine aminotransferase 1

0.736

0.308

1.9E-12

CUI:	C1269683
Disease:	Major Depressive Disorder

Major Depressive Disorder

disease

0.310

None

< 0.001

2012

Entrez Id:	25823
Gene Symbol:	TPSG1

TPSG1

tryptase gamma 1

0.638

0.500

7.6E-15

CUI:	C1269683
Disease:	Major Depressive Disorder

Major Depressive Disorder

disease

0.010

None

< 0.001

2019

Entrez Id:	50846
Gene Symbol:	DHH

DHH

desert hedgehog signaling molecule

0.650

0.423

0.22

CUI:	C1269683
Disease:	Major Depressive Disorder

Major Depressive Disorder

disease

0.010

None

< 0.001

2014

Entrez Id:	2869
Gene Symbol:	GRK5

GRK5

G protein-coupled receptor kinase 5

0.588

0.769

0.68

CUI:	C1269683
Disease:	Major Depressive Disorder

Major Depressive Disorder

disease

0.310

None

< 0.001

2010

Entrez Id:	2556
Gene Symbol:	GABRA3

GABRA3

gamma-aminobutyric acid type A receptor subunit alpha3

0.636

0.577

3.9E-02

CUI:	C1269683
Disease:	Major Depressive Disorder

Major Depressive Disorder

disease

0.010

None

< 0.001

2004

Entrez Id:	4049
Gene Symbol:	LTA

LTA

lymphotoxin alpha

0.434

0.885

0.20

CUI:	C1269683
Disease:	Major Depressive Disorder

Major Depressive Disorder

disease

0.310

None

< 0.001

2003

Entrez Id:	23373
Gene Symbol:	CRTC1

CRTC1

CREB regulated transcription coactivator 1

0.565

0.692

0.53

CUI:	C1269683
Disease:	Major Depressive Disorder

Major Depressive Disorder

disease

0.010

None

< 0.001

2016

Entrez Id:	2026
Gene Symbol:	ENO2

ENO2

enolase 2

0.475

0.846

0.38

CUI:	C1269683
Disease:	Major Depressive Disorder

Major Depressive Disorder

disease

0.010

None

< 0.001

2020

Entrez Id:	155
Gene Symbol:	ADRB3

ADRB3

adrenoceptor beta 3

0.533

0.731

2.5E-07

CUI:	C1269683
Disease:	Major Depressive Disorder

Major Depressive Disorder

disease

0.310

None

< 0.001

2012

Entrez Id:	7432
Gene Symbol:	VIP

VIP

vasoactive intestinal peptide

0.437

0.846

4.2E-04

CUI:	C1269683
Disease:	Major Depressive Disorder

Major Depressive Disorder

disease

0.310

None

< 0.001

2010

Entrez Id:	2169
Gene Symbol:	FABP2

FABP2

fatty acid binding protein 2

0.608

0.654

5.0E-03

CUI:	C1269683
Disease:	Major Depressive Disorder

Major Depressive Disorder

disease

0.010

None

< 0.001

2013

Entrez Id:	2166
Gene Symbol:	FAAH

FAAH

fatty acid amide hydrolase

0.545

0.692

4.4E-11

CUI:	C1269683
Disease:	Major Depressive Disorder

Major Depressive Disorder

disease

0.310

None

< 0.001

2010

Entrez Id:	9572
Gene Symbol:	NR1D1

NR1D1

nuclear receptor subfamily 1 group D member 1

0.608

0.692

0.82

CUI:	C1269683
Disease:	Major Depressive Disorder

Major Depressive Disorder

disease

0.010

None

< 0.001

2009

Entrez Id:	9531
Gene Symbol:	BAG3

BAG3

BAG cochaperone 3

0.498

0.846

0.62

CUI:	C1269683
Disease:	Major Depressive Disorder

Major Depressive Disorder

disease

0.010

None

< 0.001

2017

Entrez Id:	5824
Gene Symbol:	PEX19

PEX19

peroxisomal biogenesis factor 19

0.585

0.731

3.2E-04

CUI:	C1269683
Disease:	Major Depressive Disorder

Major Depressive Disorder

disease

0.310

None

< 0.001

2011

Entrez Id:	259217
Gene Symbol:	HSPA12A

HSPA12A

heat shock protein family A (Hsp70) member 12A

0.670

0.346

0.98

CUI:	C1269683
Disease:	Major Depressive Disorder

Major Depressive Disorder

disease

0.310

None

< 0.001

2004

Entrez Id:	23413
Gene Symbol:	NCS1

NCS1

neuronal calcium sensor 1

0.656

0.615

0.66

CUI:	C1269683
Disease:	Major Depressive Disorder

Major Depressive Disorder

disease

0.010

None

< 0.001

2019

Entrez Id:	29949
Gene Symbol:	IL19

IL19

interleukin 19

0.558

0.769

4.3E-05

CUI:	C1269683
Disease:	Major Depressive Disorder

Major Depressive Disorder

disease

0.310

None

< 0.001

2002