Source: LHGDN

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 55054
Gene Symbol: ATG16L1
ATG16L1
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		0.700 GeneticVariation LHGDN A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1. 17200669

2007
Entrez Id: 55054
Gene Symbol: ATG16L1
ATG16L1
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		0.700 Biomarker LHGDN A nonsynonymous SNP in ATG16L1 predisposes to ileal Crohn's disease and is independent of CARD15 and IBD5. 17484864

2007
Entrez Id: 55054
Gene Symbol: ATG16L1
ATG16L1
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		0.700 GeneticVariation LHGDN Association of the T300A non-synonymous variant of the ATG16L1 gene with susceptibility to paediatric Crohn's disease. 17625155

2007
Entrez Id: 55054
Gene Symbol: ATG16L1
ATG16L1
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		0.700 Biomarker LHGDN ATG16L1 and IL23 receptor (IL23R) genes are associated with disease susceptibility in Hungarian CD patients. 18499543

2008
Entrez Id: 55054
Gene Symbol: ATG16L1
ATG16L1
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		0.700 GeneticVariation LHGDN Replication of interleukin 23 receptor and autophagy-related 16-like 1 association in adult- and pediatric-onset inflammatory bowel disease in Italy. 18698678

2008
Entrez Id: 55054
Gene Symbol: ATG16L1
ATG16L1
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		0.700 Biomarker LHGDN The critical next step is functional characterization of the CD-associated genetic variants in IRGM and ATG16L. 17921695

2008
Entrez Id: 55054
Gene Symbol: ATG16L1
ATG16L1
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		0.700 Biomarker LHGDN Thus, we propose that the association of ATG16L1*300A with increased risk of Crohn's disease is due to impaired bacterial handling and lowered rates of bacterial capture by autophagy. 18852889

2008
Entrez Id: 55054
Gene Symbol: ATG16L1
ATG16L1
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		0.700 Biomarker LHGDN We replicated the previously reported associations between CD and rs11209026 and rs2241880, confirming that IL23R and ATG16L1 are susceptibility loci for CD in the New Zealand population. 17894849

2007
Entrez Id: 55054
Gene Symbol: ATG16L1
ATG16L1
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		0.700 Biomarker LHGDN With respect to ATG16L1, the G allele of SNP rs2241880 has been shown in multiple association studies to confer strong risk for CD, although its association with UC remains more debatable. 18366306

2008