Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 6775
Gene Symbol: STAT4
STAT4
signal transducer and activator of transcription 4 0.471 0.769 0.77
CUI: C0036421
Disease: Systemic Scleroderma
Systemic Scleroderma
disease 0.500 None 1.000 22 8 2009 2019
Entrez Id: 23534
Gene Symbol: TNPO3
TNPO3
transportin 3 0.663 0.577 1.8E-06
CUI: C0036421
Disease: Systemic Scleroderma
Systemic Scleroderma
disease 0.110 None 1.000 5 8 2014 2020
Entrez Id: 7292
Gene Symbol: TNFSF4
TNFSF4
TNF superfamily member 4 0.540 0.808 4.9E-02
CUI: C0036421
Disease: Systemic Scleroderma
Systemic Scleroderma
disease 0.040 None 1.000 4 8 2010 2018
Entrez Id: 10318
Gene Symbol: TNIP1
TNIP1
TNFAIP3 interacting protein 1 0.564 0.769 0.48
CUI: C0036421
Disease: Systemic Scleroderma
Systemic Scleroderma
disease 0.440 None 0.857 7 5 2011 2019
Entrez Id: 9474
Gene Symbol: ATG5
ATG5
autophagy related 5 0.462 0.885 0.98
CUI: C0036421
Disease: Systemic Scleroderma
Systemic Scleroderma
disease 0.100 None 1.000 5 5 2013 2019
Entrez Id: 933
Gene Symbol: CD22
CD22
CD22 molecule 0.556 0.615 0.80
CUI: C0036421
Disease: Systemic Scleroderma
Systemic Scleroderma
disease 0.040 None 0.750 4 4 2007 2018
Entrez Id: 3684
Gene Symbol: ITGAM
ITGAM
integrin subunit alpha M 0.443 0.808 3.3E-11
CUI: C0036421
Disease: Systemic Scleroderma
Systemic Scleroderma
disease 0.120 None 1.000 3 4 2011 2013
Entrez Id: 3569
Gene Symbol: IL6
IL6
interleukin 6 0.248 0.962 0.32
CUI: C0036421
Disease: Systemic Scleroderma
Systemic Scleroderma
disease 0.100 None 1.000 41 3 1992 2019
Entrez Id: 3663
Gene Symbol: IRF5
IRF5
interferon regulatory factor 5 0.489 0.731 9.0E-03
CUI: C0036421
Disease: Systemic Scleroderma
Systemic Scleroderma
disease 0.500 None 1.000 15 3 2009 2020
Entrez Id: 3115
Gene Symbol: HLA-DPB1
HLA-DPB1
major histocompatibility complex, class II, DP beta 1 0.453 0.923 5.3E-10
CUI: C0036421
Disease: Systemic Scleroderma
Systemic Scleroderma
disease 0.180 None 1.000 9 3 1996 2017
Entrez Id: 931
Gene Symbol: MS4A1
MS4A1
membrane spanning 4-domains A1 0.411 0.846 5.1E-05
CUI: C0036421
Disease: Systemic Scleroderma
Systemic Scleroderma
disease 0.060 None 0.833 6 3 2003 2018
Entrez Id: 55024
Gene Symbol: BANK1
BANK1
B cell scaffold protein with ankyrin repeats 1 0.653 0.538 4.8E-12
CUI: C0036421
Disease: Systemic Scleroderma
Systemic Scleroderma
disease 0.050 None 1.000 5 3 2009 2012
Entrez Id: 3595
Gene Symbol: IL12RB2
IL12RB2
interleukin 12 receptor subunit beta 2 0.608 0.692 1.6E-09
CUI: C0036421
Disease: Systemic Scleroderma
Systemic Scleroderma
disease 0.110 None 1.000 5 3 2012 2019
Entrez Id: 4855
Gene Symbol: NOTCH4
NOTCH4
notch receptor 4 0.534 0.731 2.1E-23
CUI: C0036421
Disease: Systemic Scleroderma
Systemic Scleroderma
disease 0.120 None 1.000 3 3 2010 2016
Entrez Id: 54899
Gene Symbol: PXK
PXK
PX domain containing serine/threonine kinase like 0.821 0.231 1.1E-02
CUI: C0036421
Disease: Systemic Scleroderma
Systemic Scleroderma
disease 0.120 None 1.000 3 3 2013 2019
Entrez Id: 1235
Gene Symbol: CCR6
CCR6
C-C motif chemokine receptor 6 0.485 0.808 5.8E-03
CUI: C0036421
Disease: Systemic Scleroderma
Systemic Scleroderma
disease 0.020 None 1.000 2 3 2013 2015
Entrez Id: 100287722
Gene Symbol: AP4B1-AS1
AP4B1-AS1
AP4B1 antisense RNA 1 0.805 0.231
CUI: C0036421
Disease: Systemic Scleroderma
Systemic Scleroderma
disease 0.100 None 1.000 1 3 2019 2019
Entrez Id: 7148
Gene Symbol: TNXB
TNXB
tenascin XB 0.572 0.731 1.9E-02
CUI: C0036421
Disease: Systemic Scleroderma
Systemic Scleroderma
disease 0.100 None 1.000 1 3 2010 2010
Entrez Id: 57661
Gene Symbol: PHRF1
PHRF1
PHD and ring finger domains 1 0.743 0.346 5.7E-02
CUI: C0036421
Disease: Systemic Scleroderma
Systemic Scleroderma
disease 0.100 None 1.000 1 3 2013 2013
Entrez Id: 100847070
Gene Symbol: MIR5196
MIR5196
microRNA 5196 0.821 0.115
CUI: C0036421
Disease: Systemic Scleroderma
Systemic Scleroderma
disease 0.010 None 1.000 1 3 2017 2017
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
interleukin 1 beta 0.276 0.962 0.13
CUI: C0036421
Disease: Systemic Scleroderma
Systemic Scleroderma
disease 0.100 None 1.000 25 2 1992 2019
Entrez Id: 3552
Gene Symbol: IL1A
IL1A
interleukin 1 alpha 0.333 0.962 1.6E-04
CUI: C0036421
Disease: Systemic Scleroderma
Systemic Scleroderma
disease 0.100 None 0.957 23 2 1992 2019
Entrez Id: 26191
Gene Symbol: PTPN22
PTPN22
protein tyrosine phosphatase non-receptor type 22 0.438 0.846 3.5E-21
CUI: C0036421
Disease: Systemic Scleroderma
Systemic Scleroderma
disease 0.190 None 0.800 10 2 2006 2019
Entrez Id: 50943
Gene Symbol: FOXP3
FOXP3
forkhead box P3 0.368 0.846 0.99
CUI: C0036421
Disease: Systemic Scleroderma
Systemic Scleroderma
disease 0.090 None 0.778 9 2 2010 2020
Entrez Id: 7128
Gene Symbol: TNFAIP3
TNFAIP3
TNF alpha induced protein 3 0.481 0.808 1.00
CUI: C0036421
Disease: Systemic Scleroderma
Systemic Scleroderma
disease 0.170 None 1.000 8 2 2010 2017