Source: ANIMAL_MODELS

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
CUI: C0018800
Disease: Cardiomegaly
Cardiomegaly
0.200 Biomarker RGD Atorvastatin attenuating down-regulation of peroxisome proliferator-activated receptor gamma in preventing cardiac hypertrophy of rats in vitro and in vivo. 17207419

2006

Entrez Id: 4318
Gene Symbol: MMP9
MMP9
CUI: C0162820
Disease: Dermatitis, Allergic Contact
Dermatitis, Allergic Contact
0.200 Biomarker RGD Gene expression profiling of skin and draining lymph nodes of rats affected with cutaneous contact hypersensitivity. 16977379

2006

Entrez Id: 4318
Gene Symbol: MMP9
MMP9
CUI: C3714630
Disease: Respirovirus Infections
Respirovirus Infections
0.200 Biomarker RGD Sendai virus infection up-regulates trypsin I and matrix metalloproteinase-9, triggering viral multiplication and matrix degradation in rat lungs and lung L2 cells. 16816895

2006

Entrez Id: 4318
Gene Symbol: MMP9
MMP9
CUI: C0034065
Disease: Pulmonary Embolism
Pulmonary Embolism
0.200 Biomarker RGD L-arginine attenuates acute pulmonary embolism-induced increases in lung matrix metalloproteinase-2 and matrix metalloproteinase-9. 16304337

2005

Entrez Id: 4318
Gene Symbol: MMP9
MMP9
CUI: C0242706
Disease: Hyperoxia
Hyperoxia
0.200 Biomarker RGD Hyperoxia decreases matrix metalloproteinase-9 and increases tissue inhibitor of matrix metalloproteinase-1 protein in the newborn rat lung: association with arrested alveolarization. 15128910

2004

Entrez Id: 4318
Gene Symbol: MMP9
MMP9
CUI: C0280725
Disease: Adult Cholangiocarcinoma
Adult Cholangiocarcinoma
0.200 Biomarker RGD Expression of epidermal growth factor receptor, apomucins, matrix metalloproteinases, and p53 in rat and human cholangiocarcinoma: appraisal of an animal model of cholangiocarcinoma. 15213623

2004

Entrez Id: 4318
Gene Symbol: MMP9
MMP9
CUI: C0020544
Disease: Renal hypertension
Renal hypertension
0.200 Biomarker RGD Mechanism of matrix accumulation and glomerulosclerosis in spontaneously hypertensive rats. 12923405

2003

Entrez Id: 4318
Gene Symbol: MMP9
MMP9
CUI: C0160390
Disease: Injury of liver
Injury of liver
0.200 Biomarker RGD Expression of matrix metalloproteinases and their inhibitors during hepatic tissue repair in the rat. 10933221

2000

Entrez Id: 4318
Gene Symbol: MMP9
MMP9
Experimental Autoimmune Encephalomyelitis
0.200 Biomarker RGD In the present study we investigated the expression of 92-kDa gelatinase (MMP-9) in spinal cord from animals with adoptive transfer experimental autoimmune encephalomyelitis (AT-EAE), using a semiquantitative competitive reverse transcriptase-polymerase chain reaction assay. 9549496

1998

Entrez Id: 4318
Gene Symbol: MMP9
MMP9
CUI: C0027814
Disease: Neuritis, Autoimmune, Experimental
Neuritis, Autoimmune, Experimental
0.200 Biomarker RGD Matrix metalloproteinases MMP-9 and MMP-7 are expressed in experimental autoimmune neuritis and the Guillain-Barré syndrome. 9546322

1998

Entrez Id: 4318
Gene Symbol: MMP9
MMP9
CUI: C0017665
Disease: Membranous glomerulonephritis
Membranous glomerulonephritis
0.200 Biomarker RGD Characterization of a glomerular epithelial cell metalloproteinase as matrix metalloproteinase-9 with enhanced expression in a model of membranous nephropathy. 8613533

1996

Entrez Id: 4318
Gene Symbol: MMP9
MMP9
CUI: C0025295
Disease: Meningitis, Pneumococcal
Meningitis, Pneumococcal
0.210 Therapeutic RGD Inhibition of matrix metalloproteinases-2 and -9 prevents cognitive impairment induced by pneumococcal meningitis in Wistar rats. 24419461

2014

Entrez Id: 4318
Gene Symbol: MMP9
MMP9
CUI: C0085762
Disease: Alcohol abuse
Alcohol abuse
0.210 Biomarker RGD These results suggest that MMP-2 and MMP-9 may play a significant role in blood-brain barrier disruption after alcohol abuse. 24966898

2014

Entrez Id: 4318
Gene Symbol: MMP9
MMP9
CUI: C0019156
Disease: Hepatic Veno-Occlusive Disease
Hepatic Veno-Occlusive Disease
0.210 Biomarker RGD Expression of MMP-9 in hepatic sinusoidal obstruction syndrome induced by Gynura segetum. 23303633

2013

Entrez Id: 4318
Gene Symbol: MMP9
MMP9
Delirium, Dementia, Amnestic, Cognitive Disorders
0.210 Biomarker RGD Myelin loss associated with neuroinflammation in hypertensive rats. 22363061

2012

Entrez Id: 4318
Gene Symbol: MMP9
MMP9
CUI: C0178664
Disease: Glomerulosclerosis (disorder)
Glomerulosclerosis (disorder)
0.210 Biomarker RGD NMDA receptor-mediated activation of NADPH oxidase and glomerulosclerosis in hyperhomocysteinemic rats. 20406136

2010

Entrez Id: 4318
Gene Symbol: MMP9
MMP9
CUI: C0017668
Disease: Focal glomerulosclerosis
Focal glomerulosclerosis
0.210 Biomarker RGD Effect of all-trans retinoic acid on renal expressions of matrix metalloproteinase-2, matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 in rats with glomerulosclerosis. 19357873

2009

Entrez Id: 4318
Gene Symbol: MMP9
MMP9
CUI: C0003855
Disease: Arteriovenous fistula
Arteriovenous fistula
0.210 Biomarker RGD Femoral AVF resulted in a sixfold increase in blood flow in the fistula iliac vein and a gradual, but significant, increase in the thickness of the intima and media and marked up-regulation of MMP-2 and MMP-9, down-regulation of TIMP-4, as well as degradation of collagens I and III. 17398390

2007

Entrez Id: 4318
Gene Symbol: MMP9
MMP9
CUI: C0025295
Disease: Meningitis, Pneumococcal
Meningitis, Pneumococcal
0.210 Biomarker RGD Prevention of brain injury by the nonbacteriolytic antibiotic daptomycin in experimental pneumococcal meningitis. 17371820

2007

Entrez Id: 4318
Gene Symbol: MMP9
MMP9
CUI: C0038220
Disease: Status Epilepticus
Status Epilepticus
0.210 Biomarker RGD Synaptic localization of seizure-induced matrix metalloproteinase-9 mRNA. 17928157

2007

Entrez Id: 4318
Gene Symbol: MMP9
MMP9
Idiopathic crescentic glomerulonephritis
0.210 Biomarker RGD Expression of matrix metalloproteinase-9 associated with ets-1 proto-oncogene in rat tubulointerstitial cells. 16046515

2005

Entrez Id: 4318
Gene Symbol: MMP9
MMP9
CUI: C0025294
Disease: Meningococcal meningitis
Meningococcal meningitis
0.210 Biomarker RGD Differential expression of matrix metalloproteinases in bacterial meningitis. 10430840

1999

Entrez Id: 4318
Gene Symbol: MMP9
MMP9
CUI: C0178664
Disease: Glomerulosclerosis (disorder)
Glomerulosclerosis (disorder)
0.210 Biomarker RGD Differential regulation of glomerular gelatinase B (MMP-9) and tissue inhibitor of metalloproteinase-1 (TIMP-1) in obese Zucker rats. 9300240

1997

Entrez Id: 4318
Gene Symbol: MMP9
MMP9
CUI: C0007787
Disease: Transient Ischemic Attack
Transient Ischemic Attack
0.220 Therapeutic RGD Rapamycin alleviates brain edema after focal cerebral ischemia reperfusion in rats. 24773551

2014

Entrez Id: 4318
Gene Symbol: MMP9
MMP9
CUI: C0007787
Disease: Transient Ischemic Attack
Transient Ischemic Attack
0.220 Therapeutic RGD Melatonin reduced the elevated matrix metalloproteinase-9 level in a rat photothrombotic stroke model. 23046750

2012