×
Entrez Id:
11200
Gene Symbol:
CHEK2
CHEK2
Mammary Neoplasms
0.500
GeneticVariation
LHGDN
CHEK2 1100delC mutation is frequent among Russian breast cancer patients.
16758118
2006
×
Entrez Id:
11200
Gene Symbol:
CHEK2
CHEK2
Mammary Neoplasms
0.500
GeneticVariation
LHGDN
Association between the CHEK2*1100delC germ line mutation and estrogen receptor status.
17010071
2006
×
Entrez Id:
11200
Gene Symbol:
CHEK2
CHEK2
Mammary Neoplasms
0.500
GeneticVariation
LHGDN
Pathology of breast cancer in women with constitutional CHEK2 mutations.
15803365
2005
×
Entrez Id:
11200
Gene Symbol:
CHEK2
CHEK2
Mammary Neoplasms
0.500
GeneticVariation
LHGDN
Functional and genomic approaches reveal an ancient CHEK2 allele associated with breast cancer in the Ashkenazi Jewish population.
15649950
2005
×
Entrez Id:
11200
Gene Symbol:
CHEK2
CHEK2
Mammary Neoplasms
0.500
GeneticVariation
LHGDN
The CHEK2 c.1100delC germline mutation rarely contributes to breast cancer development in the Czech Republic.
15803363
2005
×
Entrez Id:
11200
Gene Symbol:
CHEK2
CHEK2
Mammary Neoplasms
0.500
GeneticVariation
LHGDN
Low frequency of CHEK2 1100delC allele in Australian multiple-case breast cancer families: functional analysis in heterozygous individuals.
15700044
2005
×
Entrez Id:
11200
Gene Symbol:
CHEK2
CHEK2
Mammary Neoplasms
0.500
GeneticVariation
LHGDN
We have here studied CHEK2 protein expression by immunohistochemistry on a tissue microarray of 611 unselected breast tumors and also evaluated the tumor characteristics among 1,297 unselected breast cancer patients defined for the c.1100delC germ line mutation status (2.5% carrier frequency).
15472904
2005
×
Entrez Id:
11200
Gene Symbol:
CHEK2
CHEK2
Mammary Neoplasms
0.500
GeneticVariation
LHGDN
Chromosomal radiosensitivity of breast cancer with a CHEK2 mutation.
16337852
2005
×
Entrez Id:
11200
Gene Symbol:
CHEK2
CHEK2
Mammary Neoplasms
0.500
GeneticVariation
LHGDN
Tumour characteristics and prognosis of breast cancer patients carrying the germline CHEK2*1100delC variant.
15466005
2004
×
Entrez Id:
11200
Gene Symbol:
CHEK2
CHEK2
Mammary Neoplasms
0.500
Biomarker
LHGDN
CHEK2*1100delC and susceptibility to breast cancer: a collaborative analysis involving 10,860 breast cancer cases and 9,065 controls from 10 studies.
15122511
2004
×
Entrez Id:
11200
Gene Symbol:
CHEK2
CHEK2
Mammary Neoplasms
0.500
GeneticVariation
LHGDN
Chk2 phosphorylation of BRCA1 regulates DNA double-strand break repair.
14701743
2004
×
Entrez Id:
11200
Gene Symbol:
CHEK2
CHEK2
Mammary Neoplasms
0.500
GeneticVariation
LHGDN
Limited relevance of the CHEK2 gene in hereditary breast cancer.
15095295
2004
×
Entrez Id:
11200
Gene Symbol:
CHEK2
CHEK2
Mammary Neoplasms
0.500
GeneticVariation
LHGDN
Low-penetrance susceptibility to breast cancer due to CHEK2(*)1100delC in noncarriers of BRCA1 or BRCA2 mutations.
11967536
2002
×
Entrez Id:
11200
Gene Symbol:
CHEK2
CHEK2
Mammary Neoplasms
0.500
Biomarker
LHGDN
CHEKs and balances: accounting for breast cancer.
11984555
2002
×
Entrez Id:
11200
Gene Symbol:
CHEK2
CHEK2
Mammary Neoplasms
0.500
GeneticVariation
LHGDN
Finally, tissue microarray analysis indicated that breast tumors from patients with 1100delC mutations show reduced CHEK2 immunostaining.
12094328
2002