×
Entrez Id: 348
Gene Symbol: APOE
APOE
Alzheimer's Disease
0.700
Biomarker
LHGDN
Second, the APOE gene is the only gene so far recognized as a consistent genetic determinant of sporadic forms of AD , even though numerous studies have looked for such genes; these disappointing results suggest persistent methodological limitations.
17659844 2007
×
Entrez Id: 348
Gene Symbol: APOE
APOE
Alzheimer's Disease
0.700
GeneticVariation
LHGDN
Real-time multiplex PCR assay for genotyping of three apolipoprotein E alleles and two choline acetyltransferase alleles with three hybridization probes.
17378730 2007
×
Entrez Id: 348
Gene Symbol: APOE
APOE
Alzheimer's Disease
0.700
Biomarker
LHGDN
Predictive utility of apolipoprotein E genotype for Alzheimer disease in outpatients with mild cognitive impairment.
15956169 2005
×
Entrez Id: 348
Gene Symbol: APOE
APOE
Alzheimer's Disease
0.700
PosttranslationalModification
LHGDN
Neuron-specific proteolytic cleavage of apoE4 is associated with increased phosphorylation of tau and may play a key role in the development of AD -related neuronal deficits.
15014128 2004
×
Entrez Id: 348
Gene Symbol: APOE
APOE
Alzheimer's Disease
0.700
Biomarker
LHGDN
Marked regional differences of brain human apolipoprotein E expression in targeted replacement mice.
15026113 2004
×
Entrez Id: 348
Gene Symbol: APOE
APOE
Alzheimer's Disease
0.700
GeneticVariation
LHGDN
In order to clarify the role of the polymorphism for the occurrence of LOAD in Chinese and the possibility of a synergistic effect with the apolipoprotein E allele 4 on the risk of Alzheimer disease , we examined the ACE and APOE genotypes in a Chinese sample consisting of 104 sporadic LOAD patients and 128 healthy controls.
17401152 2006
×
Entrez Id: 348
Gene Symbol: APOE
APOE
Alzheimer's Disease
0.700
GeneticVariation
LHGDN
Heparan sulfate proteoglycan 2 polymorphism in Alzheimer's disease and correlation with neuropathology.
14625044 2003
×
Entrez Id: 348
Gene Symbol: APOE
APOE
Alzheimer's Disease
0.700
GeneticVariation
LHGDN
Genome-wide association analysis reveals putative Alzheimer's disease susceptibility loci in addition to APOE.
18976728 2008
×
Entrez Id: 348
Gene Symbol: APOE
APOE
Alzheimer's Disease
0.700
Biomarker
LHGDN
Diabetes and overweight associate with non-APOE4 genotype in an Alzheimer's disease population.
18189240 2008
×
Entrez Id: 348
Gene Symbol: APOE
APOE
Alzheimer's Disease
0.700
GeneticVariation
LHGDN
Determination of malondialdehyde, reduced glutathione levels and APOE4 allele frequency in late-onset Alzheimer's disease in Denizli, Turkey.
17069783 2007
×
Entrez Id: 348
Gene Symbol: APOE
APOE
Alzheimer's Disease
0.700
GeneticVariation
LHGDN
Delusion symptoms are associated with ApoE epsilon4 allelic variant at the early stage of Alzheimer's disease with late onset.
16490049 2006
×
Entrez Id: 348
Gene Symbol: APOE
APOE
Alzheimer's Disease
0.700
Biomarker
LHGDN
Coronary artery disease is associated with Alzheimer disease neuropathology in APOE4 carriers.
17283328 2007
×
Entrez Id: 348
Gene Symbol: APOE
APOE
Alzheimer's Disease
0.700
GeneticVariation
LHGDN
Cerebral cortical arteriolar angiopathy, vascular beta-amyloid, smooth muscle actin, Braak stage, and APOE genotype.
18258839 2008
×
Entrez Id: 348
Gene Symbol: APOE
APOE
Alzheimer's Disease
0.700
Biomarker
LHGDN
Because the structural and biophysical properties of a protein determine how it functions under normal and abnormal conditions, apoE4 , with its multiple cellular origins and multiple structural and biophysical properties, might contribute to the pathology of AD through several different mechanisms.
15181247 2004
×
Entrez Id: 348
Gene Symbol: APOE
APOE
Alzheimer's Disease
0.700
GeneticVariation
LHGDN
Association between the APOE genotype and psychopathologic symptoms in Alzheimer's disease .
11971084 2002
×
Entrez Id: 348
Gene Symbol: APOE
APOE
Alzheimer's Disease
0.700
Biomarker
LHGDN
Apolipoprotein E4 (apoE4 ) is a risk factor for developing AD at an earlier age and might contribute to this effect.
17710250 2007
×
Entrez Id: 348
Gene Symbol: APOE
APOE
Alzheimer's Disease
0.700
GeneticVariation
LHGDN
Apolipoprotein E polymorphism and brain morphology in mild cognitive impairment.
18843182 2008
×
Entrez Id: 348
Gene Symbol: APOE
APOE
Alzheimer's Disease
0.700
GeneticVariation
LHGDN
Apolipoprotein E gene in frontotemporal dementia: an association study and meta-analysis.
12107813 2002
×
Entrez Id: 348
Gene Symbol: APOE
APOE
Alzheimer's Disease
0.700
GeneticVariation
LHGDN
Apolipoprotein E epsilon 4 allele frequency in demented and cognitively impaired patients with and without cerebrovascular disease.
12417380 2002
×
Entrez Id: 348
Gene Symbol: APOE
APOE
Alzheimer's Disease
0.700
GeneticVariation
LHGDN
ApoE-epsilon 4-dependent association of the choline acetyltransferase gene polymorphisms (2384G>A and 1882G>A) with Alzheimer's disease.
16480703 2006
×
Entrez Id: 348
Gene Symbol: APOE
APOE
Alzheimer's Disease
0.700
Biomarker
LHGDN
APOE genotype, family history of dementia, and Alzheimer disease risk: a 6-year follow-up study.
15596614 2004
×
Entrez Id: 348
Gene Symbol: APOE
APOE
Alzheimer's Disease
0.700
GeneticVariation
LHGDN
APOE genotype and survival in men and women with Alzheimer's disease.
11940690 2002
×
Entrez Id: 348
Gene Symbol: APOE
APOE
Alzheimer's Disease
0.700
GeneticVariation
LHGDN
ApoE epsilon4 allele is associated with incidental hallucinations and delusions in patients with AD.
15452311 2004
×
Entrez Id: 348
Gene Symbol: APOE
APOE
Alzheimer's Disease
0.700
GeneticVariation
LHGDN
ApoE epsilon3-haplotype modulates Alzheimer beta-amyloid deposition in the brain.
11920850 2002
×
Entrez Id: 348
Gene Symbol: APOE
APOE
Alzheimer's Disease
0.700
GeneticVariation
LHGDN
Analysis of association between butyrylcholinesterase K variant and apolipoprotein E genotypes in Alzheimer's disease .
15519745 2004