Source: CLINVAR

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4893
Gene Symbol: NRAS
NRAS
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.800 CausalMutation CLINVAR

Entrez Id: 4893
Gene Symbol: NRAS
NRAS
CUI: C1842036
Disease: GIANT PIGMENTED HAIRY NEVUS
GIANT PIGMENTED HAIRY NEVUS 		0.700 CausalMutation CLINVAR

Entrez Id: 4893
Gene Symbol: NRAS
NRAS
CUI: C2674723
Disease: RAS-ASSOCIATED AUTOIMMUNE LEUKOPROLIFERATIVE DISORDER
RAS-ASSOCIATED AUTOIMMUNE LEUKOPROLIFERATIVE DISORDER 		0.700 CausalMutation CLINVAR

Entrez Id: 4893
Gene Symbol: NRAS
NRAS
CUI: C2750732
Disease: Noonan Syndrome 6
Noonan Syndrome 6 		0.700 CausalMutation CLINVAR

Entrez Id: 4893
Gene Symbol: NRAS
NRAS
CUI: C0265329
Disease: Organoid Nevus Phakomatosis
Organoid Nevus Phakomatosis 		0.600 CausalMutation CLINVAR

Entrez Id: 4893
Gene Symbol: NRAS
NRAS
CUI: C0334082
Disease: NEVUS, EPIDERMAL (disorder)
NEVUS, EPIDERMAL (disorder) 		0.600 CausalMutation CLINVAR

Entrez Id: 4893
Gene Symbol: NRAS
NRAS
CUI: C0544862
Disease: Neurocutaneous melanosis
Neurocutaneous melanosis 		0.600 CausalMutation CLINVAR

Entrez Id: 4893
Gene Symbol: NRAS
NRAS
CUI: C4552097
Disease: Nevus Sebaceus of Jadassohn
Nevus Sebaceus of Jadassohn 		0.600 CausalMutation CLINVAR

Entrez Id: 4893
Gene Symbol: NRAS
NRAS
CUI: C4225426
Disease: THYROID CANCER, NONMEDULLARY, 2
THYROID CANCER, NONMEDULLARY, 2 		0.400 CausalMutation CLINVAR

Entrez Id: 4893
Gene Symbol: NRAS
NRAS
CUI: C4551602
Disease: Noonan Syndrome 1
Noonan Syndrome 1 		0.400 CausalMutation CLINVAR

Entrez Id: 4893
Gene Symbol: NRAS
NRAS
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		0.460 CausalMutation CLINVAR Mechanism of activation of an N-ras oncogene of SW-1271 human lung carcinoma cells. 6587382

1984
Entrez Id: 4893
Gene Symbol: NRAS
NRAS
CUI: C0023467
Disease: Leukemia, Myelocytic, Acute
Leukemia, Myelocytic, Acute 		0.700 GeneticVariation CLINVAR RAS gene mutations in acute and chronic myelocytic leukemias, chronic myeloproliferative disorders, and myelodysplastic syndromes. 3122217

1987
Entrez Id: 4893
Gene Symbol: NRAS
NRAS
CUI: C0025202
Disease: melanoma
melanoma 		0.700 CausalMutation CLINVAR N-ras mutations in human cutaneous melanoma from sun-exposed body sites. 2674680

1989
Entrez Id: 4893
Gene Symbol: NRAS
NRAS
CUI: C0023467
Disease: Leukemia, Myelocytic, Acute
Leukemia, Myelocytic, Acute 		0.700 GeneticVariation CLINVAR RAS gene mutations in childhood acute myeloid leukemia: a Pediatric Oncology Group study. 2278970

1990
Entrez Id: 4893
Gene Symbol: NRAS
NRAS
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		0.460 CausalMutation CLINVAR ras gene mutations in non-small cell lung cancers are associated with shortened survival irrespective of treatment intent. 1654209

1991
Entrez Id: 4893
Gene Symbol: NRAS
NRAS
CUI: C0025202
Disease: melanoma
melanoma 		0.700 CausalMutation CLINVAR Ras mutations in human melanoma: a marker of malignant progression. 8120410

1994
Entrez Id: 4893
Gene Symbol: NRAS
NRAS
CUI: C0349639
Disease: Juvenile Myelomonocytic Leukemia
Juvenile Myelomonocytic Leukemia 		0.800 CausalMutation CLINVAR Juvenile myelomonocytic leukemia and Noonan syndrome. 10598665

2000
Entrez Id: 4893
Gene Symbol: NRAS
NRAS
CUI: C0028326
Disease: Noonan Syndrome
Noonan Syndrome 		0.780 CausalMutation CLINVAR Juvenile myelomonocytic leukemia and Noonan syndrome. 10598665

2000
Entrez Id: 4893
Gene Symbol: NRAS
NRAS
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		0.460 CausalMutation CLINVAR BRAF and RAS mutations in human lung cancer and melanoma. 12460918

2002
Entrez Id: 4893
Gene Symbol: NRAS
NRAS
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		0.460 CausalMutation CLINVAR BRAF mutations in papillary carcinomas of the thyroid. 14508525

2003
Entrez Id: 4893
Gene Symbol: NRAS
NRAS
CUI: C0028326
Disease: Noonan Syndrome
Noonan Syndrome 		0.780 CausalMutation CLINVAR Genetic evidence for lineage-related and differentiation stage-related contribution of somatic PTPN11 mutations to leukemogenesis in childhood acute leukemia. 14982869

2004
Entrez Id: 4893
Gene Symbol: NRAS
NRAS
CUI: C0028326
Disease: Noonan Syndrome
Noonan Syndrome 		0.780 CausalMutation CLINVAR Constitutive activation of the Ras-Raf signaling pathway in metastatic melanoma is associated with poor prognosis. 15046639

2004
Entrez Id: 4893
Gene Symbol: NRAS
NRAS
CUI: C0028326
Disease: Noonan Syndrome
Noonan Syndrome 		0.780 CausalMutation CLINVAR Repressible transgenic model of NRAS oncogene-driven mast cell disease in the mouse. 15831708

2005
Entrez Id: 4893
Gene Symbol: NRAS
NRAS
CUI: C0025202
Disease: melanoma
melanoma 		0.700 CausalMutation CLINVAR Distinct sets of genetic alterations in melanoma. 16291983

2005
Entrez Id: 4893
Gene Symbol: NRAS
NRAS
CUI: C0349639
Disease: Juvenile Myelomonocytic Leukemia
Juvenile Myelomonocytic Leukemia 		0.800 CausalMutation CLINVAR Mutations of the PTPN11 and RAS genes in rhabdomyosarcoma and pediatric hematological malignancies. 16518851

2006