×
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
Carcinoma, Ovarian Epithelial
0.100
AlteredExpression
BEFREE
Expression of vascular endothelial growth factor and its receptors flt and KDR in ovarian carcinoma .
7707437 1995
×
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
Carcinoma, Ovarian Epithelial
0.100
AlteredExpression
BEFREE
Abundant levels of VPF have been identified by an immunoassay in the ascites of patients with epithelial ovarian cancer (K-T. Yeo et al., Cancer Res., 53: 2912-2918, 1993).
8261452 1994
×
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
Carcinoma, Ovarian Epithelial
0.100
AlteredExpression
BEFREE
Neutralization of VEGF activity may have clinical application in inhibiting malignant ascites formation in ovarian cancer .
9777956 1998
×
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
Carcinoma, Ovarian Epithelial
0.100
Biomarker
BEFREE
Advanced EOC is associated with raised serum and ascitic bFGF concentrations and with markedly elevated ascitic VEGF in most cases.
9815846 1997
×
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
Carcinoma, Ovarian Epithelial
0.100
AlteredExpression
BEFREE
Prognostic significance of vascular endothelial growth factor expression in human ovarian carcinoma .
10901370 2000
×
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
Carcinoma, Ovarian Epithelial
0.100
Biomarker
BEFREE
These observations suggest that VEGF may play a role in the development of ovarian cancer and that the elevated gonadotropins, as found in menopause and in most ovarian cancer patients after surgery, could accelerate tumor growth and tumor recurrence by inducing VEGF expression in OETs.
11774259 2002
×
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
Carcinoma, Ovarian Epithelial
0.100
AlteredExpression
BEFREE
The aim of this study was to examine the expression of HIF-1 alpha and VEGF gene expressions and their relation to angiogenesis, clinicopathologic variables and survival in the patient with human ovarian carcinoma .
11804750 2002
×
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
Carcinoma, Ovarian Epithelial
0.100
Biomarker
BEFREE
Vascular endothelial growth factor (VEGF ) is suggested to be an important regulator of angiogenesis in ovarian cancer .11839574 2002
×
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
Carcinoma, Ovarian Epithelial
0.100
GeneticVariation
BEFREE
Vascular endothelial growth factor splice variants and their prognostic value in breast and ovarian cancer .12114428 2002
×
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
Carcinoma, Ovarian Epithelial
0.100
Biomarker
BEFREE
Generation of a syngeneic mouse model to study the effects of vascular endothelial growth factor in ovarian carcinoma .
12466143 2002
×
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
Carcinoma, Ovarian Epithelial
0.100
AlteredExpression
BEFREE
We first used immunohistochemistry to examine the expression of VEGF in 42 cases of ovarian carcinoma , with relevance to the p53 expression.
12529984 2003
×
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
Carcinoma, Ovarian Epithelial
0.100
AlteredExpression
BEFREE
We analyzed the expression of LPA receptors, vascular endothelial growth factor (VEGF), and interleukin-8 in 97 patients from normal ovary to ovarian cancer , using reverse transcription polymerase chain reaction.
12668280 2003
×
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
Carcinoma, Ovarian Epithelial
0.100
AlteredExpression
BEFREE
Expression of VEGF mRNA was variable, but not significantly different between the 3 histological types of ovarian cancer .
12684660 2003
×
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
Carcinoma, Ovarian Epithelial
0.100
AlteredExpression
BEFREE
Tumor-derived vascular endothelial growth factor up-regulates angiopoietin-2 in host endothelium and destabilizes host vasculature, supporting angiogenesis in ovarian cancer .
12810677 2003
×
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
Carcinoma, Ovarian Epithelial
0.100
Biomarker
BEFREE
The oncogene phosphatidylinositol 3'-kinase catalytic subunit alpha promotes angiogenesis via vascular endothelial growth factor in ovarian carcinoma .
12874030 2003
×
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
Carcinoma, Ovarian Epithelial
0.100
AlteredExpression
BEFREE
COX-2 status in relation to tumor microvessel density and VEGF expression: analysis in ovarian carcinoma patients with low versus high survival rates.
14719060 2004
×
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
Carcinoma, Ovarian Epithelial
0.100
AlteredExpression
BEFREE
Angiopoietin-1 (Ang-1), Angiopoietin-2 (Ang-2), Tie2, and VEGF gene expression were analyzed by real-time quantitative reverse transcription-polymerase chain reaction (RT-PCR) in 85 epithelial ovarian cancer surgical specimens.
15047239 2004
×
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
Carcinoma, Ovarian Epithelial
0.100
Biomarker
BEFREE
VEGF mean rank was significantly higher in ovarian cancer tumors compared to benign lesions (P < 0.001).15087251 2004
×
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
Carcinoma, Ovarian Epithelial
0.100
Biomarker
BEFREE
Vascular endothelial growth factor (VEGF ) plays an important role in ovarian cancer development.15213310 2004
×
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
Carcinoma, Ovarian Epithelial
0.100
AlteredExpression
BEFREE
The objective of this study was to investigate the effects of prostaglandin E(2) (PGE(2)) on the expression of vascular endothelial growth factor (VEGF ) and hypoxia-inducible transcription factor-1 alpha (HIF-1alpha) genes in epithelial ovarian cancer (EOC ) cells.
15297183 2004
×
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
Carcinoma, Ovarian Epithelial
0.100
Biomarker
BEFREE
Cisplatin reduced the tumor burden and ascites in mice bearing 1A9 -VS-1; the response was associated with a significant decrease of VEGF in plasma.
15897235 2005
×
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
Carcinoma, Ovarian Epithelial
0.100
Biomarker
BEFREE
In summary, our results indicate that VEGF may regulate EOC invasion and migration through VEGFR-mediated secretion and activation of MMPs.
16152587 2006
×
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
Carcinoma, Ovarian Epithelial
0.100
Biomarker
BEFREE
Comparison of ID8 MOSE and VEGF -modified ID8 cell lines in an immunocompetent animal model for human ovarian cancer .
16886597 2006
×
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
Carcinoma, Ovarian Epithelial
0.100
AlteredExpression
BEFREE
The abundance of NGF and trkA receptors in epithelial cells of EOC, together with the ability of NGF to increase VEGF expression strongly suggests an autocrine role of NGF in EOC .
16935322 2007
×
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
Carcinoma, Ovarian Epithelial
0.100
Biomarker
BEFREE
To clarify the involvement of SEMA and VEGF in the development and progression of ovarian carcinoma , we analyzed the immunohistochemical expression of SEMA, VEGF, NP1, and NP2 in 105 epithelial ovarian tumors.
17010410 2006