×
Entrez Id: 5979
Gene Symbol: RET
RET
Neoplastic Syndromes, Hereditary
0.200
CausalMutation
CLINVAR
"Familial associations in medullary thyroid carcinoma with Hirschsprung disease: the role of the RET-C620 ""Janus"" genetic variation."
20152359 2010
×
Entrez Id: 5979
Gene Symbol: RET
RET
Neoplastic Syndromes, Hereditary
0.200
Biomarker
BEFREE
RET is also the predisposition gene for the inherited cancer syndrome MEN 2A.7716719 1995
×
Entrez Id: 5979
Gene Symbol: RET
RET
Neoplastic Syndromes, Hereditary
0.200
CausalMutation
CLINVAR
Actionable exomic incidental findings in 6503 participants: challenges of variant classification.
25637381 2015
×
Entrez Id: 5979
Gene Symbol: RET
RET
Neoplastic Syndromes, Hereditary
0.200
CausalMutation
CLINVAR
Predominant RET Germline Mutations in Exons 10, 11, and 16 in Iranian Patients with Hereditary Medullary Thyroid Carcinoma.
21765987 2011
×
Entrez Id: 5979
Gene Symbol: RET
RET
Neoplastic Syndromes, Hereditary
0.200
CausalMutation
CLINVAR
RET revisited: expanding the oncogenic portfolio.
24561444 2014
×
Entrez Id: 5979
Gene Symbol: RET
RET
Neoplastic Syndromes, Hereditary
0.200
CausalMutation
CLINVAR
Patients with RET D631Y mutations most commonly present with pheochromocytoma and not medullary thyroid carcinoma.
22274720 2012
×
Entrez Id: 5979
Gene Symbol: RET
RET
Neoplastic Syndromes, Hereditary
0.200
CausalMutation
CLINVAR
A newly identified missense mutation in RET codon 666 is associated with the development of medullary thyroid carcinoma.
25319874 2014
×
Entrez Id: 5979
Gene Symbol: RET
RET
Neoplastic Syndromes, Hereditary
0.200
CausalMutation
CLINVAR
Case report: a p.C618S RET proto-oncogene germline mutation in a large Chinese pedigree with familial medullary thyroid carcinoma.
22068382 2012
×
Entrez Id: 5979
Gene Symbol: RET
RET
Neoplastic Syndromes, Hereditary
0.200
CausalMutation
CLINVAR
Molecular diagnosis and comprehensive treatment of multiple endocrine neoplasia type 2 in Southeastern Chinese.
25628771 2015
×
Entrez Id: 5979
Gene Symbol: RET
RET
Neoplastic Syndromes, Hereditary
0.200
CausalMutation
CLINVAR
Patient affected by neurofibromatosis type 1 and thyroid C-cell hyperplasia harboring pathogenic germ-line mutations in both NF1 and RET genes.
24361808 2014
×
Entrez Id: 5979
Gene Symbol: RET
RET
Neoplastic Syndromes, Hereditary
0.200
CausalMutation
CLINVAR
Multiple endocrine neoplasia type 2: evaluation of the genotype-phenotype relationship.
12686527 2003
×
Entrez Id: 5979
Gene Symbol: RET
RET
Neoplastic Syndromes, Hereditary
0.200
CausalMutation
CLINVAR
Prevalence of germline mutations in patients with pheochromocytoma or abdominal paraganglioma and sporadic presentation: a population-based study in Western Sweden.
22270996 2012
×
Entrez Id: 5979
Gene Symbol: RET
RET
Neoplastic Syndromes, Hereditary
0.200
CausalMutation
CLINVAR
Skewed mutational spectrum of RET proto-oncogene Exon10 in Iranian patients with medullary thyroid carcinoma.
25694125 2015
×
Entrez Id: 5979
Gene Symbol: RET
RET
Neoplastic Syndromes, Hereditary
0.200
CausalMutation
CLINVAR
The clinical spectrum of RET proto-oncogene mutations in codon 790.
23756355 2013
×
Entrez Id: 5979
Gene Symbol: RET
RET
Neoplastic Syndromes, Hereditary
0.200
CausalMutation
CLINVAR
The rare intracellular RET mutation p.S891A in a Chinese Han family with familial medullary thyroid carcinoma.
24845513 2014
×
Entrez Id: 5979
Gene Symbol: RET
RET
Neoplastic Syndromes, Hereditary
0.200
CausalMutation
CLINVAR
A new hot spot for mutations in the ret protooncogene causing familial medullary thyroid carcinoma and multiple endocrine neoplasia type 2A.
9506724 1998
×
Entrez Id: 5979
Gene Symbol: RET
RET
Neoplastic Syndromes, Hereditary
0.200
CausalMutation
CLINVAR
Hirschsprung disease in MEN 2A: increased spectrum of RET exon 10 genotypes and strong genotype-phenotype correlation.
9384613 1998
×
Entrez Id: 5979
Gene Symbol: RET
RET
Neoplastic Syndromes, Hereditary
0.200
CausalMutation
CLINVAR
Specific mutations of the RET proto-oncogene are related to disease phenotype in MEN 2A and FMTC.
7907913 1994
×
Entrez Id: 5979
Gene Symbol: RET
RET
Neoplastic Syndromes, Hereditary
0.200
AlteredExpression
BEFREE
Germ-line mutations, mainly point mutations, that lead to constitutive activation of RET tyrosine kinase activity are responsible for the development of the inherited cancer syndrome , multiple endocrine neoplasia type 2.
11114739 2000
×
Entrez Id: 5979
Gene Symbol: RET
RET
Neoplastic Syndromes, Hereditary
0.200
CausalMutation
CLINVAR
Various penetrance of familial medullary thyroid carcinoma in patients with RET protooncogene codon 790/791 germline mutations.
12409662 2002
×
Entrez Id: 5979
Gene Symbol: RET
RET
Neoplastic Syndromes, Hereditary
0.200
CausalMutation
CLINVAR
Genetic testing in medullary thyroid carcinoma syndromes: mutation types and clinical significance.
9146685 1997
×
Entrez Id: 5979
Gene Symbol: RET
RET
Neoplastic Syndromes, Hereditary
0.200
CausalMutation
CLINVAR
Coexistence of multiple endocrine neoplasia type 1 and type 2 in a large Italian family.
21678021 2011
×
Entrez Id: 5979
Gene Symbol: RET
RET
Neoplastic Syndromes, Hereditary
0.200
CausalMutation
CLINVAR
How to Assess the Clinical Relevance of Novel RET Missense Variants in the Absence of Functional Studies?
27099842 2016
×
Entrez Id: 5979
Gene Symbol: RET
RET
Neoplastic Syndromes, Hereditary
0.200
CausalMutation
CLINVAR
Genotype-specific progression of hereditary medullary thyroid cancer.
29656518 2018
×
Entrez Id: 5979
Gene Symbol: RET
RET
Neoplastic Syndromes, Hereditary
0.200
CausalMutation
CLINVAR
Protecting thyroid cancer patients from untoward effects of radioactive iodine treatment.
19731974 2009