Source: CURATED

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0003129
Disease: Anoxemia
Anoxemia 		0.300 Biomarker CTD_human Proopiomelanocortin gene delivery induces apoptosis in melanoma through NADPH oxidase 4-mediated ROS generation. 24412703

2014
Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0003130
Disease: Anoxia
Anoxia 		0.300 Biomarker CTD_human We further showed that POMC-derived melanocortins, including α-MSH, β-MSH, and ACTH, but not γ-MSH, contributed to POMC-induced apoptosis and ROS generation during hypoxia. 24412703

2014
Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0242184
Disease: Hypoxia
Hypoxia 		0.300 Biomarker CTD_human We further showed that POMC-derived melanocortins, including α-MSH, β-MSH, and ACTH, but not γ-MSH, contributed to POMC-induced apoptosis and ROS generation during hypoxia. 24412703

2014
Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0700292
Disease: Hypoxemia
Hypoxemia 		0.300 Biomarker CTD_human Proopiomelanocortin gene delivery induces apoptosis in melanoma through NADPH oxidase 4-mediated ROS generation. 24412703

2014
Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0086237
Disease: Epilepsy, Cryptogenic
Epilepsy, Cryptogenic 		0.300 Therapeutic CTD_human Polymicrogyria and infantile spasms in a patient with 1p36 deletion syndrome. 20708863

2011
Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0236018
Disease: Aura
Aura 		0.300 Therapeutic CTD_human Polymicrogyria and infantile spasms in a patient with 1p36 deletion syndrome. 20708863

2011
Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0751111
Disease: Awakening Epilepsy
Awakening Epilepsy 		0.300 Therapeutic CTD_human Polymicrogyria and infantile spasms in a patient with 1p36 deletion syndrome. 20708863

2011
Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0086189
Disease: Drug Withdrawal Symptoms
Drug Withdrawal Symptoms 		0.300 Biomarker CTD_human Circadian alteration in neurobiology during protracted opiate withdrawal in rats. 20738730

2010
Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0086189
Disease: Drug Withdrawal Symptoms
Drug Withdrawal Symptoms 		0.300 Therapeutic CTD_human Circadian alteration in neurobiology during protracted opiate withdrawal in rats. 20738730

2010
Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0234230
Disease: Pain, Burning
Pain, Burning 		0.300 Biomarker CTD_human Serum beta-endorphin response to stress before and after operation under fentanyl anesthesia in neonates, infants and preschool children. 20084599

2010
Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0234230
Disease: Pain, Burning
Pain, Burning 		0.300 Therapeutic CTD_human Serum beta-endorphin response to stress before and after operation under fentanyl anesthesia in neonates, infants and preschool children. 20084599

2010
Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0234238
Disease: Ache
Ache 		0.300 Therapeutic CTD_human Serum beta-endorphin response to stress before and after operation under fentanyl anesthesia in neonates, infants and preschool children. 20084599

2010
Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0234238
Disease: Ache
Ache 		0.300 Biomarker CTD_human Serum beta-endorphin response to stress before and after operation under fentanyl anesthesia in neonates, infants and preschool children. 20084599

2010
Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0234254
Disease: Radiating pain
Radiating pain 		0.300 Therapeutic CTD_human Serum beta-endorphin response to stress before and after operation under fentanyl anesthesia in neonates, infants and preschool children. 20084599

2010
Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0234254
Disease: Radiating pain
Radiating pain 		0.300 Biomarker CTD_human Serum beta-endorphin response to stress before and after operation under fentanyl anesthesia in neonates, infants and preschool children. 20084599

2010
Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0458257
Disease: Pain, Splitting
Pain, Splitting 		0.300 Biomarker CTD_human Serum beta-endorphin response to stress before and after operation under fentanyl anesthesia in neonates, infants and preschool children. 20084599

2010
Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0458257
Disease: Pain, Splitting
Pain, Splitting 		0.300 Therapeutic CTD_human Serum beta-endorphin response to stress before and after operation under fentanyl anesthesia in neonates, infants and preschool children. 20084599

2010
Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0458259
Disease: Pain, Crushing
Pain, Crushing 		0.300 Therapeutic CTD_human Serum beta-endorphin response to stress before and after operation under fentanyl anesthesia in neonates, infants and preschool children. 20084599

2010
Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0458259
Disease: Pain, Crushing
Pain, Crushing 		0.300 Biomarker CTD_human Serum beta-endorphin response to stress before and after operation under fentanyl anesthesia in neonates, infants and preschool children. 20084599

2010
Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0546878
Disease: Nodding spasm
Nodding spasm 		0.300 Biomarker CTD_human Clinical profile and treatment of infantile spasms using vigabatrin and ACTH--a developing country perspective. 20078871

2010
Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0546878
Disease: Nodding spasm
Nodding spasm 		0.300 Therapeutic CTD_human Clinical profile and treatment of infantile spasms using vigabatrin and ACTH--a developing country perspective. 20078871

2010
Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0553558
Disease: Jackknife Seizures
Jackknife Seizures 		0.300 Therapeutic CTD_human Clinical profile and treatment of infantile spasms using vigabatrin and ACTH--a developing country perspective. 20078871

2010
Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0553558
Disease: Jackknife Seizures
Jackknife Seizures 		0.300 Biomarker CTD_human Clinical profile and treatment of infantile spasms using vigabatrin and ACTH--a developing country perspective. 20078871

2010
Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0574960
Disease: Sacroiliitis
Sacroiliitis 		0.300 Therapeutic CTD_human We report a case of acute sacroiliitis with severe disability after only 3 weeks of isotretinoin therapy with graduate reduction of pain, limitation and muscle incompetence after discontinuation of the drug and ACTH-depo injection and Ethodolac therapy. 19533139

2010
Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0684276
Disease: Hypsarrhythmia
Hypsarrhythmia 		0.300 Biomarker CTD_human Clinical profile and treatment of infantile spasms using vigabatrin and ACTH--a developing country perspective. 20078871

2010