Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6390
Gene Symbol: SDHB
SDHB
CUI: C0238198
Disease: Gastrointestinal Stromal Tumors
Gastrointestinal Stromal Tumors
0.800 CausalMutation CLINVAR Effects of compression on physiologic integrity of the spinal cord, on circulation, and clinical status in four different directions of compression: posterior, anterior, circumferential, and lateral. 1523504

1992

Entrez Id: 6390
Gene Symbol: SDHB
SDHB
CUI: C0238198
Disease: Gastrointestinal Stromal Tumors
Gastrointestinal Stromal Tumors
0.800 GeneticVariation CLINVAR The effect of some anti-inflammatory agents on elastase release from neutrophils in-vitro. 1980289

1990

Entrez Id: 6390
Gene Symbol: SDHB
SDHB
CUI: C0238198
Disease: Gastrointestinal Stromal Tumors
Gastrointestinal Stromal Tumors
0.800 GeneticVariation CLINVAR Age-related changes of the ciliary muscle in comparison with changes induced by treatment with prostaglandin F2 alpha. An ultrastructural study in rhesus and cynomolgus monkeys. 2308387

1990

Entrez Id: 6390
Gene Symbol: SDHB
SDHB
CUI: C0238198
Disease: Gastrointestinal Stromal Tumors
Gastrointestinal Stromal Tumors
0.800 GeneticVariation CLINVAR How general practitioners manage depressive illness: developing a method of audit. 7143317

1982

Entrez Id: 6390
Gene Symbol: SDHB
SDHB
CUI: C0238198
Disease: Gastrointestinal Stromal Tumors
Gastrointestinal Stromal Tumors
0.800 CausalMutation CLINVAR Gene mutations in the succinate dehydrogenase subunit SDHB cause susceptibility to familial pheochromocytoma and to familial paraganglioma. 11404820

2001

Entrez Id: 6390
Gene Symbol: SDHB
SDHB
CUI: C0238198
Disease: Gastrointestinal Stromal Tumors
Gastrointestinal Stromal Tumors
0.800 CausalMutation CLINVAR Germ-line mutations in nonsyndromic pheochromocytoma. 12000816

2002

Entrez Id: 6390
Gene Symbol: SDHB
SDHB
CUI: C0238198
Disease: Gastrointestinal Stromal Tumors
Gastrointestinal Stromal Tumors
0.800 GeneticVariation CLINVAR Germ-line mutations in nonsyndromic pheochromocytoma. 12000816

2002

Entrez Id: 6390
Gene Symbol: SDHB
SDHB
CUI: C0238198
Disease: Gastrointestinal Stromal Tumors
Gastrointestinal Stromal Tumors
0.800 GeneticVariation CLINVAR Novel succinate dehydrogenase subunit B (SDHB) mutations in familial phaeochromocytomas and paragangliomas, but an absence of somatic SDHB mutations in sporadic phaeochromocytomas. 12618761

2003

Entrez Id: 6390
Gene Symbol: SDHB
SDHB
CUI: C0238198
Disease: Gastrointestinal Stromal Tumors
Gastrointestinal Stromal Tumors
0.800 CausalMutation CLINVAR Novel succinate dehydrogenase subunit B (SDHB) mutations in familial phaeochromocytomas and paragangliomas, but an absence of somatic SDHB mutations in sporadic phaeochromocytomas. 12618761

2003

Entrez Id: 6390
Gene Symbol: SDHB
SDHB
CUI: C0238198
Disease: Gastrointestinal Stromal Tumors
Gastrointestinal Stromal Tumors
0.800 GeneticVariation CLINVAR Mutations in the SDHB gene are associated with extra-adrenal and/or malignant phaeochromocytomas. 14500403

2003

Entrez Id: 6390
Gene Symbol: SDHB
SDHB
CUI: C0238198
Disease: Gastrointestinal Stromal Tumors
Gastrointestinal Stromal Tumors
0.800 CausalMutation CLINVAR Mutations in the SDHB gene are associated with extra-adrenal and/or malignant phaeochromocytomas. 14500403

2003

Entrez Id: 6390
Gene Symbol: SDHB
SDHB
CUI: C0238198
Disease: Gastrointestinal Stromal Tumors
Gastrointestinal Stromal Tumors
0.800 CausalMutation CLINVAR Distinct clinical features of paraganglioma syndromes associated with SDHB and SDHD gene mutations. 15328326

2004

Entrez Id: 6390
Gene Symbol: SDHB
SDHB
CUI: C0238198
Disease: Gastrointestinal Stromal Tumors
Gastrointestinal Stromal Tumors
0.800 GeneticVariation CLINVAR Distinct clinical features of paraganglioma syndromes associated with SDHB and SDHD gene mutations. 15328326

2004

Entrez Id: 6390
Gene Symbol: SDHB
SDHB
CUI: C0238198
Disease: Gastrointestinal Stromal Tumors
Gastrointestinal Stromal Tumors
0.800 CausalMutation CLINVAR Accumulation of Krebs cycle intermediates and over-expression of HIF1alpha in tumours which result from germline FH and SDH mutations. 15987702

2005

Entrez Id: 6390
Gene Symbol: SDHB
SDHB
CUI: C0238198
Disease: Gastrointestinal Stromal Tumors
Gastrointestinal Stromal Tumors
0.800 CausalMutation CLINVAR Pediatric paraganglioma: an early manifestation of an adult disease secondary to germline mutations. 16304664

2006

Entrez Id: 6390
Gene Symbol: SDHB
SDHB
CUI: C0238198
Disease: Gastrointestinal Stromal Tumors
Gastrointestinal Stromal Tumors
0.800 CausalMutation CLINVAR Genetic testing in pheochromocytoma or functional paraganglioma. 16314641

2005

Entrez Id: 6390
Gene Symbol: SDHB
SDHB
CUI: C0238198
Disease: Gastrointestinal Stromal Tumors
Gastrointestinal Stromal Tumors
0.800 GeneticVariation CLINVAR Genetic testing in pheochromocytoma or functional paraganglioma. 16314641

2005

Entrez Id: 6390
Gene Symbol: SDHB
SDHB
CUI: C0238198
Disease: Gastrointestinal Stromal Tumors
Gastrointestinal Stromal Tumors
0.800 GeneticVariation CLINVAR Clinical presentation and penetrance of pheochromocytoma/paraganglioma syndromes. 16317055

2006

Entrez Id: 6390
Gene Symbol: SDHB
SDHB
CUI: C0238198
Disease: Gastrointestinal Stromal Tumors
Gastrointestinal Stromal Tumors
0.800 CausalMutation CLINVAR Clinical presentation and penetrance of pheochromocytoma/paraganglioma syndromes. 16317055

2006

Entrez Id: 6390
Gene Symbol: SDHB
SDHB
CUI: C0238198
Disease: Gastrointestinal Stromal Tumors
Gastrointestinal Stromal Tumors
0.800 CausalMutation CLINVAR Mutation analysis of SDHB and SDHC: novel germline mutations in sporadic head and neck paraganglioma and familial paraganglioma and/or pheochromocytoma. 16405730

2006

Entrez Id: 6390
Gene Symbol: SDHB
SDHB
CUI: C0238198
Disease: Gastrointestinal Stromal Tumors
Gastrointestinal Stromal Tumors
0.800 CausalMutation CLINVAR An apparently sporadic paraganglioma with an SDHB gene germline mutation presenting at age 68 years. 16472267

2006

Entrez Id: 6390
Gene Symbol: SDHB
SDHB
CUI: C0238198
Disease: Gastrointestinal Stromal Tumors
Gastrointestinal Stromal Tumors
0.800 CausalMutation CLINVAR High frequency of SDHB germline mutations in patients with malignant catecholamine-producing paragangliomas: implications for genetic testing. 16912137

2006

Entrez Id: 6390
Gene Symbol: SDHB
SDHB
CUI: C0238198
Disease: Gastrointestinal Stromal Tumors
Gastrointestinal Stromal Tumors
0.800 CausalMutation CLINVAR Gastrointestinal stromal tumour in succinate dehydrogenase subunit B mutation-associated familial phaeochromocytoma/paraganglioma. 16916404

2006

Entrez Id: 6390
Gene Symbol: SDHB
SDHB
CUI: C0238198
Disease: Gastrointestinal Stromal Tumors
Gastrointestinal Stromal Tumors
0.800 GeneticVariation CLINVAR Genetic mutation screening in an italian cohort of nonsyndromic pheochromocytoma/paraganglioma patients. 17102082

2006

Entrez Id: 6390
Gene Symbol: SDHB
SDHB
CUI: C0238198
Disease: Gastrointestinal Stromal Tumors
Gastrointestinal Stromal Tumors
0.800 CausalMutation CLINVAR Genetic mutation screening in an italian cohort of nonsyndromic pheochromocytoma/paraganglioma patients. 17102082

2006