×
Entrez Id: 5320
Gene Symbol: PLA2G2A
PLA2G2A
Unipolar Depression
0.010
Biomarker
BEFREE
'Mom-I don't want to hear it': Brain response to maternal praise and criticism in adolescents with major depressive disorder .
28338795 2017
×
Entrez Id: 6530
Gene Symbol: SLC6A2
SLC6A2
Unipolar Depression
0.400
GeneticVariation
BEFREE
252 unrelated Caucasian patients (f = 142; m = 110) with major depression were genotyped for NET and 5-HTT polymorphisms.
20588071 2010
×
Entrez Id: 6532
Gene Symbol: SLC6A4
SLC6A4
Unipolar Depression
0.600
GeneticVariation
BEFREE
252 unrelated Caucasian patients (f = 142; m = 110) with major depression were genotyped for NET and 5-HTT polymorphisms.
20588071 2010
×
Entrez Id: 6532
Gene Symbol: SLC6A4
SLC6A4
Unipolar Depression
0.600
GeneticVariation
BEFREE
49 patients with major depression and SSRI treatment were genotyped for the 5-HTTLPR locus including the rs25531 .
22086748 2012
×
Entrez Id: 3350
Gene Symbol: HTR1A
HTR1A
Unipolar Depression
0.400
Biomarker
BEFREE
5-HTR1A , 5-HTR2A, 5-HTR6, TPH1 and TPH2 polymorphisms and major depression .
19590397 2009
×
Entrez Id: 3356
Gene Symbol: HTR2A
HTR2A
Unipolar Depression
0.400
GeneticVariation
BEFREE
5-HTR1A, 5-HTR2A , 5-HTR6, TPH1 and TPH2 polymorphisms and major depression .
19590397 2009
×
Entrez Id: 121278
Gene Symbol: TPH2
TPH2
Unipolar Depression
0.800
GeneticVariation
BEFREE
5-HTR1A, 5-HTR2A, 5-HTR6, TPH1 and TPH2 polymorphisms and major depression .
19590397 2009
×
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
Unipolar Depression
0.600
GeneticVariation
BEFREE
5-HTTLPR and <i>MTHFR 677C</i>>T polymorphisms and response to yoga-based lifestyle intervention in major depressive disorder : A randomized active-controlled trial.
30581206 2020
×
Entrez Id: 4128
Gene Symbol: MAOA
MAOA
Unipolar Depression
0.400
PosttranslationalModification
BEFREE
94 patients of Caucasian descent with major depressive disorder (f = 61; DSM-IV) were analyzed for DNA methylation status at 43 MAO-A CpG sites via direct sequencing of sodium bisulfite treated DNA extracted from blood cells.
24809685 2015
×
Entrez Id: 627
Gene Symbol: BDNF
BDNF
Unipolar Depression
0.600
AlteredExpression
BEFREE
: The results suggest that the existence of major depression in pregnant women may negatively affect fetal circulating BDNF levels.
30905131 2019
×
Entrez Id: 348
Gene Symbol: APOE
APOE
Unipolar Depression
0.090
Biomarker
BEFREE
Major depression is an important comorbidity in Alzheimer's disease, which is definitely associated with the apolipoprotein E (apo E) polymorphism.16390369 2006
×
Entrez Id: 4128
Gene Symbol: MAOA
MAOA
Unipolar Depression
0.400
GeneticVariation
BEFREE
Major depressive disorder is a mediating factor between the monoamine oxidase A promoter polymorphism and telomeric length.17417064 2007
×
Entrez Id: 2908
Gene Symbol: NR3C1
NR3C1
Unipolar Depression
0.600
GeneticVariation
BEFREE
Unipolar depression is associated with DNA variants of the NR3C1 gene in our population.18286599 2008
×
Entrez Id: 3569
Gene Symbol: IL6
IL6
Unipolar Depression
0.600
AlteredExpression
BEFREE
Major depressive disorder is a condition associated with dysregulated cytokine levels; among these, IL6 .27796193 2017
×
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
Unipolar Depression
0.030
GeneticVariation
BEFREE
Major depressive disorder -associated SIRT1 locus affects the risk for suicide in women after middle age.31176830 2019
×
Entrez Id: 5999
Gene Symbol: RGS4
RGS4
Unipolar Depression
0.020
AlteredExpression
BEFREE
RGS4 expression was not altered in the prefrontal cortex of subjects with major depressive disorder or in monkeys treated chronically with haloperidol.11326297 2001
×
Entrez Id: 57113
Gene Symbol: TRPC7
TRPC7
Unipolar Depression
0.010
AlteredExpression
BEFREE
TRPC7 mRNA levels were significantly lower in BLCLs from BD-I patients with high BLCL [Ca(2+)]B compared with those showing normal [Ca(2+)]B (-33%, p =.017) and with BD-II patients (-48%, p =.003), major depressive disorder patients (-47%, p =.049) and healthy subjects (-33%, p =.038).11690598 2001
×
Entrez Id: 4049
Gene Symbol: LTA
LTA
Unipolar Depression
0.310
GeneticVariation
BEFREE
Tumor necrosis factor-beta gene polymorphism may not be associated with major depressive disorder in the Korean population.12519452 2003
×
Entrez Id: 348
Gene Symbol: APOE
APOE
Unipolar Depression
0.090
GeneticVariation
BEFREE
Apolipoprotein E genotype and major depression in a community of older adults. The Cache County Study.12701674 2003
×
Entrez Id: 153
Gene Symbol: ADRB1
ADRB1
Unipolar Depression
0.010
Biomarker
BEFREE
Beta-1-adrenergic receptor gene in major depression : influence on antidepressant treatment response.12815745 2003
×
Entrez Id: 1312
Gene Symbol: COMT
COMT
Unipolar Depression
0.400
Biomarker
BEFREE
Catechol-o-methyltransferase (COMT ) and proline dehydrogenase (PRODH) mRNAs in the dorsolateral prefrontal cortex in schizophrenia, bipolar disorder, and major depression .14618678 2004
×
Entrez Id: 1392
Gene Symbol: CRH
CRH
Unipolar Depression
0.600
Biomarker
BEFREE
CRH , stress, and major depression : a psychobiological interplay.15196881 2004
×
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
Unipolar Depression
0.310
GeneticVariation
BEFREE
Monocyte chemoattractant protein-1 (MCP1 ) promoter -2518 polymorphism may confer a susceptibility to major depressive disorder in the Korean population.15296827 2004
×
Entrez Id: 4128
Gene Symbol: MAOA
MAOA
Unipolar Depression
0.400
GeneticVariation
BEFREE
MAO-A gene polymorphisms are associated with major depression and sleep disturbance in males.15486489 2004
×
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
Unipolar Depression
0.060
AlteredExpression
BEFREE
Estrogen receptor alpha mRNA levels were reduced in the basomedial nucleus in major depressive disorder and bipolar disorder.15576061 2004