Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.600 Biomarker CTD_human Adrenomedullin modulates hemodynamic and cardiac effects of angiotensin II in conscious rats. 14751847

2004

Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.600 Biomarker CTD_human Because robust sex differences exist in the immune system and in hypertension, we investigated sex differences in T-cell modulation of angiotensin II-induced increases in mean arterial pressure in male (M) and female (F) wild-type and recombination-activating-gene-1-deficient (Rag1(-/-)) mice. 24935938

2014

Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.600 Therapeutic CTD_human Characterization of a stable, hypertensive rat model suitable for the consecutive evaluation of human renin inhibitors. 21393355

2011

Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.600 Biomarker CTD_human Adrenomedullin inhibits the pressor effects and decrease in renal blood flow induced by norepinephrine or angiotensin II in anesthetized rats. 11459117

2001

Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.600 Therapeutic CTD_human Impaired 3',5'-cyclic adenosine monophosphate-mediated signaling in immediate early responsive gene X-1-deficient vascular smooth muscle cells. 20713914

2010

Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.600 Therapeutic CTD_human Pressure-induced renal injury in angiotensin II versus norepinephrine-induced hypertensive rats. 19858406

2009

Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.600 Therapeutic CTD_human Effects of valsartan with or without benazepril on blood pressure, angiotensin II, and endoxin in patients with essential hypertension. 12676074

2003

Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.600 Therapeutic CTD_human Rosiglitzone suppresses angiotensin II-induced production of KLF5 and cell proliferation in rat vascular smooth muscle cells. 25874449

2015

Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.600 Therapeutic CTD_human Olmesartan improves endothelin-induced hypertension and oxidative stress in rats. 15302986

2004

Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.600 Therapeutic CTD_human The aim of this study was to investigate the effects of Angiotensin II (ANG II) receptor antagonist losartan on the blood-brain barrier (BBB) permeability in L-NAME-induced hypertension and/or in ANG II-induced acute hypertension in normotensive and hypertensive rats. 12084390

2002

Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.600 Therapeutic CTD_human Mitogen-activated protein kinase p38 target regenerating islet-derived 3γ expression is upregulated in cardiac inflammatory response in the rat heart. 27798352

2016

Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.600 Biomarker CTD_human Effects of renin-angiotensin blockade on sympathetic reactivity and beta-adrenergic pathway in the spontaneously hypertensive rat. 9260993

1997

Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.600 Therapeutic CTD_human Effect of intracarotid infusion of etoposide with angiotensin II-induced hypertension on the blood-brain barrier and the brain tissue. 1432030

1992

Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.600 Therapeutic CTD_human Airway resistance, inflammation and oxidative stress following exposure to diesel exhaust particle in angiotensin II-induced hypertension in mice. 22214961

2012

Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.600 Biomarker CTD_human These data demonstrate that the decrease in blood pressure observed after sEH inhibition in angiotensin II-induced hypertension can be attributed to an initial reduction in heart rate followed by pressure diuresis resulting from increased perfusion of the kidney. 15699457

2005

Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.600 Biomarker CTD_human Cardioprotective effects of granulocyte colony-stimulating factor in angiotensin II-induced cardiac remodelling. 18785976

2009

Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.600 Biomarker CTD_human Levosimendan improves cardiac function and survival in rats with angiotensin II-induced hypertensive heart failure. 20811386

2010

Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.600 Therapeutic CTD_human Induction of ecSOD by angiotensin II was not due to hypertension alone, because hypertension caused by norepinephrine (5.6 mg. kg-1. d-1) had no effect on ecSOD. 10400907

1999

Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.600 Biomarker CTD_human Central angiotensin II-induced Alzheimer-like tau phosphorylation in normal rat brains. 22982863

2012

Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.600 Therapeutic CTD_human Cardioprotective effects of granulocyte colony-stimulating factor in angiotensin II-induced cardiac remodelling. 18785976

2009

Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.600 Therapeutic CTD_human Because robust sex differences exist in the immune system and in hypertension, we investigated sex differences in T-cell modulation of angiotensin II-induced increases in mean arterial pressure in male (M) and female (F) wild-type and recombination-activating-gene-1-deficient (Rag1(-/-)) mice. 24935938

2014

Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.600 Biomarker CTD_human Effect of combination of valsartan with benazepril on blood pressure and left ventricular hypertrophy in SHR. 11501062

2000

Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.600 Biomarker CTD_human Effect of central RAS on one-kidney Grollman hypertension in rats and its mechanism. 1875449

1991

Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.600 Biomarker CTD_human Resveratrol attenuates angiotensin II-induced interleukin-6 expression and perivascular fibrosis. 19373235

2009

Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.600 Biomarker CTD_human The protective influence of the locus ceruleus on the blood-brain barrier. 6742791

1984