Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6790
Gene Symbol: AURKA
AURKA
CUI: C0153381
Disease: Malignant neoplasm of mouth
Malignant neoplasm of mouth
0.020 GeneticVariation BEFREE <b>Objective:</b> The objective of this study was aimed to investigate the interactions between Aurora kinase A (<i>AURKA</i>) gene polymorphisms (T91A and G169A) and smoking and their effects on the susceptibility of oral cancer. 31174434

2019

Entrez Id: 9021
Gene Symbol: SOCS3
SOCS3
CUI: C0153381
Disease: Malignant neoplasm of mouth
Malignant neoplasm of mouth
0.010 Biomarker BEFREE <i>Cis-3-O-p-</i>hydroxycinnamoyl Ursolic Acid Induced ROS-Dependent p53-Mediated Mitochondrial Apoptosis in Oral Cancer Cells. 30261716

2019

Entrez Id: 23583
Gene Symbol: SMUG1
SMUG1
CUI: C0153381
Disease: Malignant neoplasm of mouth
Malignant neoplasm of mouth
0.020 Biomarker BEFREE <sup>18</sup>F-FDG PET/CT versus CT/MR imaging for detection of neck lymph node metastasis in palpably node-negative oral cavity cancer. 31606761

2020

Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
CUI: C0153381
Disease: Malignant neoplasm of mouth
Malignant neoplasm of mouth
0.400 Biomarker BEFREE 91.1% of the oropharynx cancer patients had p16 positive tumors compared to 3.3% of oral cavity cancer. 29312616

2017

Entrez Id: 115482713
Gene Symbol: H3P10
H3P10
CUI: C0153381
Disease: Malignant neoplasm of mouth
Malignant neoplasm of mouth
0.080 Biomarker BEFREE 91.1% of the oropharynx cancer patients had p16 positive tumors compared to 3.3% of oral cavity cancer. 29312616

2017

Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C0153381
Disease: Malignant neoplasm of mouth
Malignant neoplasm of mouth
0.050 AlteredExpression BEFREE Oral cancer progression and c-erbB-2/neu proto-oncogene expression. 1355405

1992

Entrez Id: 6696
Gene Symbol: SPP1
SPP1
CUI: C0153381
Disease: Malignant neoplasm of mouth
Malignant neoplasm of mouth
0.020 Biomarker BEFREE Oral cancer is prevalent worldwide.Studies have indicated that an increase in the osteopontin (OPN) plasma level is correlated with the progression of oral cancer. 22011514

2012

Entrez Id: 11321
Gene Symbol: GPN1
GPN1
CUI: C0153381
Disease: Malignant neoplasm of mouth
Malignant neoplasm of mouth
0.410 GeneticVariation BEFREE Oral cancer was associated with two new regions, 2p23.3 (rs6547741, GPN1) and 9q34.12 (rs928674, LAMC3), and with known cancer-related loci-9p21.3 (rs8181047, CDKN2B-AS1) and 5p15.33 (rs10462706, CLPTM1L). 27749845

2016

Entrez Id: 100048912
Gene Symbol: CDKN2B-AS1
CDKN2B-AS1
CUI: C0153381
Disease: Malignant neoplasm of mouth
Malignant neoplasm of mouth
0.420 GeneticVariation BEFREE Oral cancer was associated with two new regions, 2p23.3 (rs6547741, GPN1) and 9q34.12 (rs928674, LAMC3), and with known cancer-related loci-9p21.3 (rs8181047, CDKN2B-AS1) and 5p15.33 (rs10462706, CLPTM1L). 27749845

2016

Entrez Id: 10319
Gene Symbol: LAMC3
LAMC3
CUI: C0153381
Disease: Malignant neoplasm of mouth
Malignant neoplasm of mouth
0.410 GeneticVariation BEFREE Oral cancer was associated with two new regions, 2p23.3 (rs6547741, GPN1) and 9q34.12 (rs928674, LAMC3), and with known cancer-related loci-9p21.3 (rs8181047, CDKN2B-AS1) and 5p15.33 (rs10462706, CLPTM1L). 27749845

2016

Entrez Id: 81037
Gene Symbol: CLPTM1L
CLPTM1L
CUI: C0153381
Disease: Malignant neoplasm of mouth
Malignant neoplasm of mouth
0.410 GeneticVariation BEFREE Oral cancer was associated with two new regions, 2p23.3 (rs6547741, GPN1) and 9q34.12 (rs928674, LAMC3), and with known cancer-related loci-9p21.3 (rs8181047, CDKN2B-AS1) and 5p15.33 (rs10462706, CLPTM1L). 27749845

2016

Entrez Id: 11321
Gene Symbol: GPN1
GPN1
CUI: C0153381
Disease: Malignant neoplasm of mouth
Malignant neoplasm of mouth
0.410 GeneticVariation GWASCAT Oral cancer was associated with two new regions, 2p23.3 (rs6547741, GPN1) and 9q34.12 (rs928674, LAMC3), and with known cancer-related loci-9p21.3 (rs8181047, CDKN2B-AS1) and 5p15.33 (rs10462706, CLPTM1L). 27749845

2016

Entrez Id: 11321
Gene Symbol: GPN1
GPN1
CUI: C0153381
Disease: Malignant neoplasm of mouth
Malignant neoplasm of mouth
0.410 Biomarker CTD_human Oral cancer was associated with two new regions, 2p23.3 (rs6547741, GPN1) and 9q34.12 (rs928674, LAMC3), and with known cancer-related loci-9p21.3 (rs8181047, CDKN2B-AS1) and 5p15.33 (rs10462706, CLPTM1L). 27749845

2016

Entrez Id: 10319
Gene Symbol: LAMC3
LAMC3
CUI: C0153381
Disease: Malignant neoplasm of mouth
Malignant neoplasm of mouth
0.410 Biomarker CTD_human Oral cancer was associated with two new regions, 2p23.3 (rs6547741, GPN1) and 9q34.12 (rs928674, LAMC3), and with known cancer-related loci-9p21.3 (rs8181047, CDKN2B-AS1) and 5p15.33 (rs10462706, CLPTM1L). 27749845

2016

Entrez Id: 10319
Gene Symbol: LAMC3
LAMC3
CUI: C0153381
Disease: Malignant neoplasm of mouth
Malignant neoplasm of mouth
0.410 GeneticVariation GWASCAT Oral cancer was associated with two new regions, 2p23.3 (rs6547741, GPN1) and 9q34.12 (rs928674, LAMC3), and with known cancer-related loci-9p21.3 (rs8181047, CDKN2B-AS1) and 5p15.33 (rs10462706, CLPTM1L). 27749845

2016

Entrez Id: 100048912
Gene Symbol: CDKN2B-AS1
CDKN2B-AS1
CUI: C0153381
Disease: Malignant neoplasm of mouth
Malignant neoplasm of mouth
0.420 GeneticVariation GWASCAT Oral cancer was associated with two new regions, 2p23.3 (rs6547741, GPN1) and 9q34.12 (rs928674, LAMC3), and with known cancer-related loci-9p21.3 (rs8181047, CDKN2B-AS1) and 5p15.33 (rs10462706, CLPTM1L). 27749845

2016

Entrez Id: 100048912
Gene Symbol: CDKN2B-AS1
CDKN2B-AS1
CUI: C0153381
Disease: Malignant neoplasm of mouth
Malignant neoplasm of mouth
0.420 Biomarker CTD_human Oral cancer was associated with two new regions, 2p23.3 (rs6547741, GPN1) and 9q34.12 (rs928674, LAMC3), and with known cancer-related loci-9p21.3 (rs8181047, CDKN2B-AS1) and 5p15.33 (rs10462706, CLPTM1L). 27749845

2016

Entrez Id: 81037
Gene Symbol: CLPTM1L
CLPTM1L
CUI: C0153381
Disease: Malignant neoplasm of mouth
Malignant neoplasm of mouth
0.410 GeneticVariation GWASCAT Oral cancer was associated with two new regions, 2p23.3 (rs6547741, GPN1) and 9q34.12 (rs928674, LAMC3), and with known cancer-related loci-9p21.3 (rs8181047, CDKN2B-AS1) and 5p15.33 (rs10462706, CLPTM1L). 27749845

2016

Entrez Id: 81037
Gene Symbol: CLPTM1L
CLPTM1L
CUI: C0153381
Disease: Malignant neoplasm of mouth
Malignant neoplasm of mouth
0.410 Biomarker CTD_human Oral cancer was associated with two new regions, 2p23.3 (rs6547741, GPN1) and 9q34.12 (rs928674, LAMC3), and with known cancer-related loci-9p21.3 (rs8181047, CDKN2B-AS1) and 5p15.33 (rs10462706, CLPTM1L). 27749845

2016

Entrez Id: 25859
Gene Symbol: PART1
PART1
CUI: C0153381
Disease: Malignant neoplasm of mouth
Malignant neoplasm of mouth
0.010 Biomarker BEFREE Oral Cancer Treatment Through the Ages: Part 1. 30794812

2019

Entrez Id: 9610
Gene Symbol: RIN1
RIN1
CUI: C0153381
Disease: Malignant neoplasm of mouth
Malignant neoplasm of mouth
0.010 Biomarker BEFREE RIN1 appears to be a valuable probe for investigating the process of gene amplification in general and, specifically, 11q13 amplification in oral cancer. 10825000

2000

Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
CUI: C0153381
Disease: Malignant neoplasm of mouth
Malignant neoplasm of mouth
0.100 GeneticVariation BEFREE GSTM1 null deletion was observed in 49% of oral cancer cases and 33% of control subjects. 11564581

2001

Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
CUI: C0153381
Disease: Malignant neoplasm of mouth
Malignant neoplasm of mouth
0.400 AlteredExpression BEFREE COX-2 expression was correlated to DNA content as a genetic risk marker of oral cancer. 12747975

2003

Entrez Id: 4513
Gene Symbol: COX2
COX2
CUI: C0153381
Disease: Malignant neoplasm of mouth
Malignant neoplasm of mouth
0.090 AlteredExpression BEFREE COX-2 expression was correlated to DNA content as a genetic risk marker of oral cancer. 12747975

2003

Entrez Id: 107075310
Gene Symbol: MTCO2P12
MTCO2P12
CUI: C0153381
Disease: Malignant neoplasm of mouth
Malignant neoplasm of mouth
0.080 AlteredExpression BEFREE COX-2 expression was correlated to DNA content as a genetic risk marker of oral cancer. 12747975

2003