Source: CURATED

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2260
Gene Symbol: FGFR1
FGFR1
CUI: C0205768
Disease: Subependymal Giant Cell Astrocytoma
Subependymal Giant Cell Astrocytoma 		0.300 Biomarker CTD_human Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma. 23817572

2013
Entrez Id: 2260
Gene Symbol: FGFR1
FGFR1
CUI: C0259783
Disease: mixed gliomas
mixed gliomas 		0.300 Biomarker CTD_human Whole-genome sequencing identifies genetic alterations in pediatric low-grade gliomas. 23583981

2013
Entrez Id: 2260
Gene Symbol: FGFR1
FGFR1
CUI: C0280783
Disease: Juvenile Pilocytic Astrocytoma
Juvenile Pilocytic Astrocytoma 		0.300 Biomarker CTD_human Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma. 23817572

2013
Entrez Id: 2260
Gene Symbol: FGFR1
FGFR1
CUI: C0280785
Disease: Diffuse Astrocytoma
Diffuse Astrocytoma 		0.300 Biomarker CTD_human Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma. 23817572

2013
Entrez Id: 2260
Gene Symbol: FGFR1
FGFR1
CUI: C0334579
Disease: Anaplastic astrocytoma
Anaplastic astrocytoma 		0.300 Biomarker CTD_human Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma. 23817572

2013
Entrez Id: 2260
Gene Symbol: FGFR1
FGFR1
CUI: C0334580
Disease: Protoplasmic astrocytoma
Protoplasmic astrocytoma 		0.300 Biomarker CTD_human Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma. 23817572

2013
Entrez Id: 2260
Gene Symbol: FGFR1
FGFR1
CUI: C0334581
Disease: Gemistocytic astrocytoma
Gemistocytic astrocytoma 		0.300 Biomarker CTD_human Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma. 23817572

2013
Entrez Id: 2260
Gene Symbol: FGFR1
FGFR1
CUI: C0334582
Disease: Fibrillary Astrocytoma
Fibrillary Astrocytoma 		0.300 Biomarker CTD_human Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma. 23817572

2013
Entrez Id: 2260
Gene Symbol: FGFR1
FGFR1
CUI: C0338070
Disease: Childhood Cerebral Astrocytoma
Childhood Cerebral Astrocytoma 		0.300 Biomarker CTD_human Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma. 23817572

2013
Entrez Id: 2260
Gene Symbol: FGFR1
FGFR1
CUI: C0547065
Disease: Mixed oligoastrocytoma
Mixed oligoastrocytoma 		0.300 Biomarker CTD_human Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma. 23817572

2013
Entrez Id: 2260
Gene Symbol: FGFR1
FGFR1
CUI: C0750935
Disease: Cerebral Astrocytoma
Cerebral Astrocytoma 		0.300 Biomarker CTD_human Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma. 23817572

2013
Entrez Id: 2260
Gene Symbol: FGFR1
FGFR1
CUI: C0750936
Disease: Intracranial Astrocytoma
Intracranial Astrocytoma 		0.300 Biomarker CTD_human Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma. 23817572

2013
Entrez Id: 2260
Gene Symbol: FGFR1
FGFR1
CUI: C1519086
Disease: Pilomyxoid astrocytoma
Pilomyxoid astrocytoma 		0.300 SomaticCausalMutation ORPHANET Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma. 23817572

2013
Entrez Id: 2260
Gene Symbol: FGFR1
FGFR1
CUI: C1704230
Disease: Grade I Astrocytoma
Grade I Astrocytoma 		0.300 Biomarker CTD_human Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma. 23817572

2013
Entrez Id: 2260
Gene Symbol: FGFR1
FGFR1
CUI: C0206726
Disease: gliosarcoma
gliosarcoma 		0.300 FusionGene ORPHANET Transforming fusions of FGFR and TACC genes in human glioblastoma. 22837387

2012
Entrez Id: 2260
Gene Symbol: FGFR1
FGFR1
CUI: C0334588
Disease: Giant Cell Glioblastoma
Giant Cell Glioblastoma 		0.300 FusionGene ORPHANET Transforming fusions of FGFR and TACC genes in human glioblastoma. 22837387

2012
Entrez Id: 2260
Gene Symbol: FGFR1
FGFR1
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.300 Biomarker CTD_human Discovery of 3-(2,6-dichloro-3,5-dimethoxy-phenyl)-1-{6-[4-(4-ethyl-piperazin-1-yl)-phenylamino]-pyrimidin-4-yl}-1-methyl-urea (NVP-BGJ398), a potent and selective inhibitor of the fibroblast growth factor receptor family of receptor tyrosine kinase. 21936542

2011
Entrez Id: 2260
Gene Symbol: FGFR1
FGFR1
CUI: C1257931
Disease: Mammary Neoplasms, Human
Mammary Neoplasms, Human 		0.300 Biomarker CTD_human Discovery of 3-(2,6-dichloro-3,5-dimethoxy-phenyl)-1-{6-[4-(4-ethyl-piperazin-1-yl)-phenylamino]-pyrimidin-4-yl}-1-methyl-urea (NVP-BGJ398), a potent and selective inhibitor of the fibroblast growth factor receptor family of receptor tyrosine kinase. 21936542

2011
Entrez Id: 2260
Gene Symbol: FGFR1
FGFR1
CUI: C4704874
Disease: Mammary Carcinoma, Human
Mammary Carcinoma, Human 		0.300 Biomarker CTD_human Discovery of 3-(2,6-dichloro-3,5-dimethoxy-phenyl)-1-{6-[4-(4-ethyl-piperazin-1-yl)-phenylamino]-pyrimidin-4-yl}-1-methyl-urea (NVP-BGJ398), a potent and selective inhibitor of the fibroblast growth factor receptor family of receptor tyrosine kinase. 21936542

2011
Entrez Id: 2260
Gene Symbol: FGFR1
FGFR1
CUI: C0085682
Disease: Hypophosphatemia
Hypophosphatemia 		0.300 Biomarker GENOMICS_ENGLAND Osteoglophonic dysplasia: A 'common' mutation in a rare disease. 20236123

2010
Entrez Id: 2260
Gene Symbol: FGFR1
FGFR1
CUI: C1257931
Disease: Mammary Neoplasms, Human
Mammary Neoplasms, Human 		0.300 Biomarker CTD_human FGFR1 amplification drives endocrine therapy resistance and is a therapeutic target in breast cancer. 20179196

2010
Entrez Id: 2260
Gene Symbol: FGFR1
FGFR1
CUI: C4704874
Disease: Mammary Carcinoma, Human
Mammary Carcinoma, Human 		0.300 Biomarker CTD_human FGFR1 amplification drives endocrine therapy resistance and is a therapeutic target in breast cancer. 20179196

2010
Entrez Id: 2260
Gene Symbol: FGFR1
FGFR1
CUI: C0011573
Disease: Endogenous depression
Endogenous depression 		0.300 Biomarker CTD_human Hippocampal FGF-2 and FGFR1 mRNA expression in major depression, schizophrenia and bipolar disorder. 16861106

2006
Entrez Id: 2260
Gene Symbol: FGFR1
FGFR1
CUI: C0025193
Disease: Melancholia
Melancholia 		0.300 Biomarker CTD_human Hippocampal FGF-2 and FGFR1 mRNA expression in major depression, schizophrenia and bipolar disorder. 16861106

2006
Entrez Id: 2260
Gene Symbol: FGFR1
FGFR1
CUI: C0086133
Disease: Depressive Syndrome
Depressive Syndrome 		0.300 Biomarker CTD_human Hippocampal FGF-2 and FGFR1 mRNA expression in major depression, schizophrenia and bipolar disorder. 16861106

2006