Source: CURATED

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
CUI: C4721507
Disease: Alveolitis, Fibrosing
Alveolitis, Fibrosing 		0.300 Biomarker CTD_human Aberrant expression of miR-125a-3p promotes fibroblast activation via Fyn/STAT3 pathway during silica-induced pulmonary fibrosis. 30658076

2019
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
CUI: C0027659
Disease: Neoplasms, Experimental
Neoplasms, Experimental 		0.300 Biomarker CTD_human Myeloid ERK5 deficiency suppresses tumor growth by blocking protumor macrophage polarization via STAT3 inhibition. 29507229

2018
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
CUI: C2930809
Disease: Neutropenia and hyperlymphocytosis with large granular lymphocytes
Neutropenia and hyperlymphocytosis with large granular lymphocytes 		0.300 SomaticCausalMutation ORPHANET Chronic lymphoproliferative disorder of NK-cells: A single-institution review with emphasis on relative utility of multimodality diagnostic tools. 29385279

2018
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
CUI: C4721508
Disease: Hamman-Rich Disease
Hamman-Rich Disease 		0.300 Biomarker CTD_human Comparison of the antifibrotic effects of the pan-histone deacetylase-inhibitor panobinostat versus the IPF-drug pirfenidone in fibroblasts from patients with idiopathic pulmonary fibrosis. 30481203

2018
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
CUI: C4721952
Disease: Familial Idiopathic Pulmonary Fibrosis
Familial Idiopathic Pulmonary Fibrosis 		0.300 Biomarker CTD_human Comparison of the antifibrotic effects of the pan-histone deacetylase-inhibitor panobinostat versus the IPF-drug pirfenidone in fibroblasts from patients with idiopathic pulmonary fibrosis. 30481203

2018
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
CUI: C0019207
Disease: Hepatoma, Morris
Hepatoma, Morris 		0.300 Biomarker CTD_human Janus Kinase 2 (JAK2) Dissociates Hepatosteatosis from Hepatocellular Carcinoma in Mice. 28100771

2017
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
CUI: C0019208
Disease: Hepatoma, Novikoff
Hepatoma, Novikoff 		0.300 Biomarker CTD_human Janus Kinase 2 (JAK2) Dissociates Hepatosteatosis from Hepatocellular Carcinoma in Mice. 28100771

2017
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
CUI: C0023904
Disease: Liver Neoplasms, Experimental
Liver Neoplasms, Experimental 		0.300 Biomarker CTD_human Janus Kinase 2 (JAK2) Dissociates Hepatosteatosis from Hepatocellular Carcinoma in Mice. 28100771

2017
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
CUI: C0086404
Disease: Experimental Hepatoma
Experimental Hepatoma 		0.300 Biomarker CTD_human Janus Kinase 2 (JAK2) Dissociates Hepatosteatosis from Hepatocellular Carcinoma in Mice. 28100771

2017
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
CUI: C1833104
Disease: DIABETES MELLITUS, PERMANENT NEONATAL
DIABETES MELLITUS, PERMANENT NEONATAL 		0.300 GermlineCausalMutation ORPHANET An Activating Mutation in STAT3 Results in Neonatal Diabetes Through Reduced Insulin Synthesis. 28073828

2017
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
CUI: C2930809
Disease: Neutropenia and hyperlymphocytosis with large granular lymphocytes
Neutropenia and hyperlymphocytosis with large granular lymphocytes 		0.300 SomaticCausalMutation ORPHANET The 2016 revision of the World Health Organization classification of lymphoid neoplasms. 26980727

2016
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
CUI: C0007621
Disease: Neoplastic Cell Transformation
Neoplastic Cell Transformation 		0.300 Biomarker CTD_human Niclosamide suppresses cell migration and invasion in enzalutamide resistant prostate cancer cells via Stat3-AR axis inhibition. 25970160

2015
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
CUI: C0019207
Disease: Hepatoma, Morris
Hepatoma, Morris 		0.300 Biomarker CTD_human Predominant Activation of JAK/STAT3 Pathway by Interleukin-6 Is Implicated in Hepatocarcinogenesis. 26297436

2015
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
CUI: C0019208
Disease: Hepatoma, Novikoff
Hepatoma, Novikoff 		0.300 Biomarker CTD_human Predominant Activation of JAK/STAT3 Pathway by Interleukin-6 Is Implicated in Hepatocarcinogenesis. 26297436

2015
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
CUI: C0023904
Disease: Liver Neoplasms, Experimental
Liver Neoplasms, Experimental 		0.300 Biomarker CTD_human Predominant Activation of JAK/STAT3 Pathway by Interleukin-6 Is Implicated in Hepatocarcinogenesis. 26297436

2015
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
CUI: C0086404
Disease: Experimental Hepatoma
Experimental Hepatoma 		0.300 Biomarker CTD_human Predominant Activation of JAK/STAT3 Pathway by Interleukin-6 Is Implicated in Hepatocarcinogenesis. 26297436

2015
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
CUI: C0205641
Disease: Adenocarcinoma, Basal Cell
Adenocarcinoma, Basal Cell 		0.300 Biomarker CTD_human PIAS3, SHP2 and SOCS3 Expression patterns in Cervical Cancers: Relevance with activation and resveratrol-caused inactivation of STAT3 signaling. 26432044

2015
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
CUI: C0205642
Disease: Adenocarcinoma, Oxyphilic
Adenocarcinoma, Oxyphilic 		0.300 Biomarker CTD_human PIAS3, SHP2 and SOCS3 Expression patterns in Cervical Cancers: Relevance with activation and resveratrol-caused inactivation of STAT3 signaling. 26432044

2015
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
CUI: C0205643
Disease: Carcinoma, Cribriform
Carcinoma, Cribriform 		0.300 Biomarker CTD_human PIAS3, SHP2 and SOCS3 Expression patterns in Cervical Cancers: Relevance with activation and resveratrol-caused inactivation of STAT3 signaling. 26432044

2015
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
CUI: C0205644
Disease: Carcinoma, Granular Cell
Carcinoma, Granular Cell 		0.300 Biomarker CTD_human PIAS3, SHP2 and SOCS3 Expression patterns in Cervical Cancers: Relevance with activation and resveratrol-caused inactivation of STAT3 signaling. 26432044

2015
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
CUI: C0205645
Disease: Adenocarcinoma, Tubular
Adenocarcinoma, Tubular 		0.300 Biomarker CTD_human PIAS3, SHP2 and SOCS3 Expression patterns in Cervical Cancers: Relevance with activation and resveratrol-caused inactivation of STAT3 signaling. 26432044

2015
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
CUI: C0265699
Disease: Congenital hernia of foramen of Morgagni
Congenital hernia of foramen of Morgagni 		0.300 Biomarker CTD_human Increased expression of activated pSTAT3 and PIM-1 in the pulmonary vasculature of experimental congenital diaphragmatic hernia. 25812446

2015
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
CUI: C0265700
Disease: Congenital hernia of foramen of Bochdalek
Congenital hernia of foramen of Bochdalek 		0.300 Biomarker CTD_human Increased expression of activated pSTAT3 and PIM-1 in the pulmonary vasculature of experimental congenital diaphragmatic hernia. 25812446

2015
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
CUI: C0282313
Disease: Condition, Preneoplastic
Condition, Preneoplastic 		0.300 Biomarker CTD_human Predominant Activation of JAK/STAT3 Pathway by Interleukin-6 Is Implicated in Hepatocarcinogenesis. 26297436

2015
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
CUI: C0018800
Disease: Cardiomegaly
Cardiomegaly 		0.300 Biomarker CTD_human Opposing roles of Akt and STAT3 in the protection of the maternal heart from peripartum stress. 24448315

2014