Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
CUI: C0178468
Disease: Autoimmune thyroid disease
Autoimmune thyroid disease
0.020 AlteredExpression BEFREE It has been shown that interferon-gamma (IFN gamma) can induce HLA class II antigen expression by thyroid epithelial cells and may play a role in the pathogenesis of autoimmune thyroid disease. 2161422

1990

Entrez Id: 3458
Gene Symbol: IFNG
IFNG
CUI: C0178468
Disease: Autoimmune thyroid disease
Autoimmune thyroid disease
0.020 Biomarker BEFREE The present study was initiated to characterize thyrotropin receptor (TSH-R) expression in thyroids from patients with Graves' disease, as well as parameters that influence TSH-R expression either causally, such as interferon-gamma (IFN-gamma), the leading candidate among the cytokines thought to play a key role in the initiation of autoimmune thyroid disease, or therapeutically, such as iodide, which is used to prepare patients for surgery. 8981006

1996