×
Entrez Id:
4233
Gene Symbol:
MET
MET
Papillary renal cell carcinoma, sporadic
0.300
Biomarker
CLINGEN
The receptor encoded by the human c-MET oncogene is expressed in hepatocytes, epithelial cells and solid tumors.
1917129
1991
×
Entrez Id:
4233
Gene Symbol:
MET
MET
Papillary renal cell carcinoma, sporadic
0.300
Biomarker
CLINGEN
Germline and somatic mutations in the tyrosine kinase domain of the MET proto-oncogene in papillary renal carcinomas.
9140397
1997
×
Entrez Id:
4233
Gene Symbol:
MET
MET
Papillary renal cell carcinoma, sporadic
0.300
Biomarker
CLINGEN
Activating mutations for the met tyrosine kinase receptor in human cancer.
9326629
1997
×
Entrez Id:
4233
Gene Symbol:
MET
MET
Papillary renal cell carcinoma, sporadic
0.300
Biomarker
CLINGEN
Hereditary and sporadic papillary renal carcinomas with c-met mutations share a distinct morphological phenotype.
10433944
1999
×
Entrez Id:
4233
Gene Symbol:
MET
MET
Papillary renal cell carcinoma, sporadic
0.300
Biomarker
CLINGEN
Activating Met mutations produce unique tumor profiles in mice with selective duplication of the mutant allele.
15557554
2004
×
Entrez Id:
4233
Gene Symbol:
MET
MET
Papillary renal cell carcinoma, sporadic
0.300
Biomarker
CLINGEN
The MET oncogene drives a genetic programme linking cancer to haemostasis.
15772665
2005
×
Entrez Id:
4233
Gene Symbol:
MET
MET
Papillary renal cell carcinoma, sporadic
0.300
Biomarker
CLINGEN
c-Met inhibitors with novel binding mode show activity against several hereditary papillary renal cell carcinoma-related mutations.
18055465
2008
×
Entrez Id:
997
Gene Symbol:
CDC34
CDC34
Papillary renal cell carcinoma, sporadic
0.010
AlteredExpression
BEFREE
We show that the expression of E2-EPF ubiquitin carrier protein , which targets the principal negative regulator of hypoxia-inducible factor (HIF), von Hippel-Lindau protein, for proteasome-dependent degradation, is markedly elevated in the majority of PRCC tumors exhibiting increased HIF1α expression, and is associated with poor prognosis.
21281817
2011
×
Entrez Id:
27338
Gene Symbol:
UBE2S
UBE2S
Papillary renal cell carcinoma, sporadic
0.010
AlteredExpression
BEFREE
These findings reveal deregulation of the oxygen-sensing pathway impinging on the positive feedback mechanism of HIF1-mediated regulation of E2-EPF in PRCC .
21281817
2011
×
Entrez Id:
3091
Gene Symbol:
HIF1A
HIF1A
Papillary renal cell carcinoma, sporadic
0.010
Biomarker
BEFREE
These findings reveal deregulation of the oxygen-sensing pathway impinging on the positive feedback mechanism of HIF1 -mediated regulation of E2-EPF in PRCC .
21281817
2011
×
Entrez Id:
29072
Gene Symbol:
SETD2
SETD2
Papillary renal cell carcinoma, sporadic
0.010
Biomarker
BEFREE
These findings reveal deregulation of the oxygen-sensing pathway impinging on the positive feedback mechanism of HIF1 -mediated regulation of E2-EPF in PRCC .
21281817
2011
×
Entrez Id:
3093
Gene Symbol:
UBE2K
UBE2K
Papillary renal cell carcinoma, sporadic
0.010
AlteredExpression
BEFREE
We show that the expression of E2-EPF ubiquitin carrier protein , which targets the principal negative regulator of hypoxia-inducible factor (HIF), von Hippel-Lindau protein, for proteasome-dependent degradation, is markedly elevated in the majority of PRCC tumors exhibiting increased HIF1α expression, and is associated with poor prognosis.
21281817
2011
×
Entrez Id:
369
Gene Symbol:
ARAF
ARAF
Papillary renal cell carcinoma, sporadic
0.100
GeneticVariation
CLINVAR
Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
26619011
2016
×
Entrez Id:
2475
Gene Symbol:
MTOR
MTOR
Papillary renal cell carcinoma, sporadic
0.100
GeneticVariation
CLINVAR
Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
26619011
2016
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
Papillary renal cell carcinoma, sporadic
0.100
GeneticVariation
CLINVAR
Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
26619011
2016
×
Entrez Id:
2261
Gene Symbol:
FGFR3
FGFR3
Papillary renal cell carcinoma, sporadic
0.100
GeneticVariation
CLINVAR
Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
26619011
2016
×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
Papillary renal cell carcinoma, sporadic
0.100
GeneticVariation
CLINVAR
Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
26619011
2016
×
Entrez Id:
2064
Gene Symbol:
ERBB2
ERBB2
Papillary renal cell carcinoma, sporadic
0.100
GeneticVariation
CLINVAR
Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
26619011
2016
×
Entrez Id:
5290
Gene Symbol:
PIK3CA
PIK3CA
Papillary renal cell carcinoma, sporadic
0.100
GeneticVariation
CLINVAR
Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
26619011
2016
×
Entrez Id:
6009
Gene Symbol:
RHEB
RHEB
Papillary renal cell carcinoma, sporadic
0.100
GeneticVariation
CLINVAR
Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
26619011
2016
×
Entrez Id:
55294
Gene Symbol:
FBXW7
FBXW7
Papillary renal cell carcinoma, sporadic
0.100
GeneticVariation
CLINVAR
Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
26619011
2016
×
Entrez Id:
673
Gene Symbol:
BRAF
BRAF
Papillary renal cell carcinoma, sporadic
0.100
GeneticVariation
CLINVAR
Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
26619011
2016
×
Entrez Id:
3265
Gene Symbol:
HRAS
HRAS
Papillary renal cell carcinoma, sporadic
0.100
GeneticVariation
CLINVAR
Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
26619011
2016