×
Entrez Id: 7113
Gene Symbol: TMPRSS2
TMPRSS2
Prostate carcinoma
0.100
Biomarker
BEFREE
<i>TMPRSS2 -ERG</i> Controls Luminal Epithelial Lineage and Antiandrogen Sensitivity in <i>PTEN</i> and <i>TP53</i>-Mutated Prostate Cancer .
29844131 2018
×
Entrez Id: 7113
Gene Symbol: TMPRSS2
TMPRSS2
Prostate carcinoma
0.100
Biomarker
BEFREE
<i>TMPRSS2 :ERG</i> status was assessed by IHC for presence of ERG on archival tumor specimens for 912 patients with prostate cancer, of whom 48% were ERG-positive.<b>Results:</b> In multivariable models, we found no association between regular use of aspirin and risk of <i>ERG</i>-positive prostate cancer (HR, 1.02; 95% confidence interval, 0.85-1.23), nor any association with duration or frequency of aspirin use.
30108097 2018
×
Entrez Id: 7113
Gene Symbol: TMPRSS2
TMPRSS2
Prostate carcinoma
0.100
Biomarker
BEFREE
10) gene fusion in a chronic myelogenous leukaemia cell line and the TMPRSS2 -ERG gene fusion in a prostate cancer cell line and tissues.
19136943 2009
×
Entrez Id: 7113
Gene Symbol: TMPRSS2
TMPRSS2
Prostate carcinoma
0.100
AlteredExpression
BEFREE
5' UTR control of native ERG and of Tmprss2 :ERG variants activity in prostate cancer .
23472063 2013
×
Entrez Id: 7113
Gene Symbol: TMPRSS2
TMPRSS2
Prostate carcinoma
0.100
GeneticVariation
BEFREE
Prostate cancer genes associated with TMPRSS2 -ERG gene fusion and prognostic of biochemical recurrence in multiple cohorts.20068566 2010
×
Entrez Id: 7113
Gene Symbol: TMPRSS2
TMPRSS2
Prostate carcinoma
0.100
GeneticVariation
BEFREE
Prostate cancer with large cribriform glands revealed rare TMPRSS2 -ERG gene fusion.20800881 2010
×
Entrez Id: 7113
Gene Symbol: TMPRSS2
TMPRSS2
Prostate carcinoma
0.100
Biomarker
BEFREE
Prostate cancer (PCa) tumors harboring translocations of ETS family genes with the androgen responsive TMPRSS2 gene (ETS+ tumors) provide a robust biomarker for detecting PCa in approximately 70% of patients.30367117 2019
×
Entrez Id: 7113
Gene Symbol: TMPRSS2
TMPRSS2
Prostate carcinoma
0.100
Biomarker
BEFREE
TMPRSS2 :ETV4 gene fusions define a third molecular subtype of prostate cancer .16585160 2006
×
Entrez Id: 7113
Gene Symbol: TMPRSS2
TMPRSS2
Prostate carcinoma
0.100
Biomarker
BEFREE
TMPRSS2 :ERG gene fusion associated with lethal prostate cancer in a watchful waiting cohort.17237811 2007
×
Entrez Id: 7113
Gene Symbol: TMPRSS2
TMPRSS2
Prostate carcinoma
0.100
AlteredExpression
BEFREE
TMPRSS2 localization and expression was evaluated in 415 cases of primary prostate cancer and 144 prostate cancer metastases by immunohistochemistry.18338334 2008
×
Entrez Id: 7113
Gene Symbol: TMPRSS2
TMPRSS2
Prostate carcinoma
0.100
Biomarker
BEFREE
TMPRSS2 :ERG fusions are promising prostate cancer biomarkers.18948370 2008
×
Entrez Id: 7113
Gene Symbol: TMPRSS2
TMPRSS2
Prostate carcinoma
0.100
Biomarker
BEFREE
TMPRSS2 -ERG gene fusion was recently reported as the most common gene rearrangement in prostate cancer (PCA).19029822 2009
×
Entrez Id: 7113
Gene Symbol: TMPRSS2
TMPRSS2
Prostate carcinoma
0.100
Biomarker
BEFREE
TMPRSS2 :ERG gene rearrangement appears to be an early event in prostate cancer and is not observed in benign or hyperplastic prostatic epithelium.19642730 2009
×
Entrez Id: 7113
Gene Symbol: TMPRSS2
TMPRSS2
Prostate carcinoma
0.100
GeneticVariation
BEFREE
TMPRSS2 -ERG and other gene fusions involving ETS factors and genes with strong promoter elements are common in prostate cancer .20713528 2010
×
Entrez Id: 7113
Gene Symbol: TMPRSS2
TMPRSS2
Prostate carcinoma
0.100
Biomarker
BEFREE
TMPRSS2 :ERG had the greatest discriminatory value in predicting prostate cancer (AUC = 0.77 compared with 0.65 for PCA3 and 0.72 for serum PSA alone).21600800 2013
×
Entrez Id: 7113
Gene Symbol: TMPRSS2
TMPRSS2
Prostate carcinoma
0.100
Biomarker
BEFREE
TMPRSS2 -ERG is the most common gene fusion in PCa , whereas activation of telomerase is a common feature of various malignancies.22505341 2012
×
Entrez Id: 7113
Gene Symbol: TMPRSS2
TMPRSS2
Prostate carcinoma
0.100
Biomarker
BEFREE
TMPRSS2 -ERG had independent additional predictive value to PCA3 and the ERSPC risk calculator parameters for predicting PCa .23201468 2014
×
Entrez Id: 7113
Gene Symbol: TMPRSS2
TMPRSS2
Prostate carcinoma
0.100
GeneticVariation
BEFREE
TMPRSS2 : ERG gene fusions are the most common types of gene fusions in prostate cancer .23357671 2013
×
Entrez Id: 7113
Gene Symbol: TMPRSS2
TMPRSS2
Prostate carcinoma
0.100
GeneticVariation
BEFREE
TMPRSS2 -ERG gene fusion appears to be a highly specific alteration in prostatic carcinoma that is frequently shared by small cell carcinoma.23850495 2013
×
Entrez Id: 7113
Gene Symbol: TMPRSS2
TMPRSS2
Prostate carcinoma
0.100
Biomarker
BEFREE
TMPRSS2 -ERG status is not prognostic following prostate cancer radiotherapy: implications for fusion status and DSB repair.23918607 2013
×
Entrez Id: 7113
Gene Symbol: TMPRSS2
TMPRSS2
Prostate carcinoma
0.100
Biomarker
BEFREE
TMPRSS2 -ERG is a recurrent rearrangement specific for prostate cancer , leading to the overexpression of a truncated ERG protein product that is amenable to immunohistochemical detection.24266818 2013
×
Entrez Id: 7113
Gene Symbol: TMPRSS2
TMPRSS2
Prostate carcinoma
0.100
Biomarker
BEFREE
TMPRSS2 :ERG gene fusion predicts subsequent detection of prostate cancer in patients with high-grade prostatic intraepithelial neoplasia.24297949 2014
×
Entrez Id: 7113
Gene Symbol: TMPRSS2
TMPRSS2
Prostate carcinoma
0.100
GeneticVariation
BEFREE
TMPRSS2 :ERG fusions, in combination with deletion of the phosphatase and tensin homolog (PTEN) tumor suppressor, have been suggested to cooperatively drive tumor progression in prostate cancer .24762546 2014
×
Entrez Id: 7113
Gene Symbol: TMPRSS2
TMPRSS2
Prostate carcinoma
0.100
Biomarker
BEFREE
TMPRSS2 :ETS fusions and clinicopathologic characteristics of prostate cancer patients from Eastern China.24815454 2014
×
Entrez Id: 7113
Gene Symbol: TMPRSS2
TMPRSS2
Prostate carcinoma
0.100
GeneticVariation
BEFREE
TMPRSS2 -ERG fusions are strongly linked to young patient age in low-grade prostate cancer .25015038 2014