Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 79719
Gene Symbol: AAGAB
AAGAB
CUI: C0019829
Disease: Hodgkin Disease
Hodgkin Disease
0.100 Biomarker HPO

Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0019829
Disease: Hodgkin Disease
Hodgkin Disease
0.060 GeneticVariation BEFREE Here, we studied the association between MDR1 C3435T polymorphism and susceptibility to Hodgkin lymphoma (HL) and patient's response to ABVD chemotherapy regimen. 21762523

2011

Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0019829
Disease: Hodgkin Disease
Hodgkin Disease
0.060 AlteredExpression BEFREE P-glycoprotein expression in non-Hodgkin's lymphomas of human immunodeficiency virus infected patients. 17157997

2007

Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0019829
Disease: Hodgkin Disease
Hodgkin Disease
0.060 AlteredExpression BEFREE MDR-1 expression in non-Hodgkin's lymphomas is unrelated to treatment intensity or response to therapy. 8535196

1995

Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0019829
Disease: Hodgkin Disease
Hodgkin Disease
0.060 AlteredExpression BEFREE Expression of MDR1 and MRP genes in patients with low-grade and high-grade non-Hodgkin's lymphomas with primary bone marrow involvement before and after chemotherapy was investigated. 15560070

2004

Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0019829
Disease: Hodgkin Disease
Hodgkin Disease
0.060 AlteredExpression BEFREE MMAE resistance and MDR1 expression are possible modes of BV resistance for Hodgkin lymphoma both in vitro and in patients. 25840583

2015

Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0019829
Disease: Hodgkin Disease
Hodgkin Disease
0.060 Biomarker BEFREE Inhibition of MDR1 overcomes resistance to brentuximab vedotin in Hodgkin lymphoma. 31811017

2020

Entrez Id: 4363
Gene Symbol: ABCC1
ABCC1
CUI: C0019829
Disease: Hodgkin Disease
Hodgkin Disease
0.010 Biomarker BEFREE Expression of MDR1 and MRP genes in patients with low-grade and high-grade non-Hodgkin's lymphomas with primary bone marrow involvement before and after chemotherapy was investigated. 15560070

2004

Entrez Id: 368
Gene Symbol: ABCC6
ABCC6
CUI: C0019829
Disease: Hodgkin Disease
Hodgkin Disease
0.010 Biomarker BEFREE Transfection of caspase-3 in the caspase-3-deficient Hodgkin's disease cell line, KMH2, results in enhanced sensitivity to CD95-, TRAIL-, and ARA-C-induced apoptosis. 11376869

2001

Entrez Id: 25
Gene Symbol: ABL1
ABL1
CUI: C0019829
Disease: Hodgkin Disease
Hodgkin Disease
0.010 GeneticVariation BEFREE Acquisition of a Ph chromosome with minor BCR/ABL fusion in treatment-related myelodysplastic syndrome with chromosome 7 abnormalities in a patient treated for Hodgkin disease. 15860359

2005

Entrez Id: 1636
Gene Symbol: ACE
ACE
CUI: C0019829
Disease: Hodgkin Disease
Hodgkin Disease
0.060 AlteredExpression BEFREE Increased levels of monocytic angiotensin-converting enzyme (ACE) found in haemodialysis (HD) patients may directly participate in the pathogenesis of atherosclerosis. 28186543

2017

Entrez Id: 1636
Gene Symbol: ACE
ACE
CUI: C0019829
Disease: Hodgkin Disease
Hodgkin Disease
0.060 GeneticVariation BEFREE The TGG (non-wild-type) haplotype, consisting of three tagging SNPs in the ACE gene, is associated with significantly decreased risk of all-cause mortality in HD patients independent of age, race, gender, and diabetic status. 16791616

2006

Entrez Id: 1636
Gene Symbol: ACE
ACE
CUI: C0019829
Disease: Hodgkin Disease
Hodgkin Disease
0.060 AlteredExpression BEFREE Increased serum calcium and serum angiotensin-converting enzyme activity have been associated with clinical sarcoidosis but have also occasionally been described in association with Hodgkin lymphoma and non-Hodgkin lymphoma without evidence of sarcoidosis. 10629150

2000

Entrez Id: 1636
Gene Symbol: ACE
ACE
CUI: C0019829
Disease: Hodgkin Disease
Hodgkin Disease
0.060 Biomarker BEFREE The ACE gene seems to be a candidate for influencing the CIMT and might therefore be involved in an HD patient's predisposition to the development of atherosclerosis. 10493570

1999

Entrez Id: 1636
Gene Symbol: ACE
ACE
CUI: C0019829
Disease: Hodgkin Disease
Hodgkin Disease
0.060 GeneticVariation BEFREE Here we determined whether angiotensin-converting enzyme (ACE) I/D polymorphism is an independent prognostic factor for AVF patency in hemodialysis (HD) patients. 19142023

2009

Entrez Id: 1636
Gene Symbol: ACE
ACE
CUI: C0019829
Disease: Hodgkin Disease
Hodgkin Disease
0.060 GeneticVariation BEFREE ACE and TNF-alpha-308 G > A (1/2) gene polymorphisms may contribute to modulation of proinflammatory cytokine production and hence chronic inflammation in HD patients. 15670287

2005

Entrez Id: 59272
Gene Symbol: ACE2
ACE2
CUI: C0019829
Disease: Hodgkin Disease
Hodgkin Disease
0.020 GeneticVariation BEFREE In this study, we investigated the correlation between serum levels of miR-421 and ACE2 transcripts in circulating leukocytes of healthy individuals (NP), CKD (3-5) and haemodialysis (HD) patients. 30326474

2019

Entrez Id: 59272
Gene Symbol: ACE2
ACE2
CUI: C0019829
Disease: Hodgkin Disease
Hodgkin Disease
0.020 AlteredExpression BEFREE In the course of a single HD session, the plasma ACE, ACE/ACE2 and Ang II levels in the HD patients with CVD were increased from pre-HD to post-HD. 29157100

2017

Entrez Id: 55289
Gene Symbol: ACOXL
ACOXL
CUI: C0019829
Disease: Hodgkin Disease
Hodgkin Disease
0.100 GeneticVariation GWASCAT Genome-wide association analysis of chronic lymphocytic leukaemia, Hodgkin lymphoma and multiple myeloma identifies pleiotropic risk loci. 28112199

2017

Entrez Id: 400997
Gene Symbol: ACOXL-AS1
ACOXL-AS1
CUI: C0019829
Disease: Hodgkin Disease
Hodgkin Disease
0.100 GeneticVariation GWASCAT Genome-wide association analysis of chronic lymphocytic leukaemia, Hodgkin lymphoma and multiple myeloma identifies pleiotropic risk loci. 28112199

2017

Entrez Id: 55
Gene Symbol: ACP3
ACP3
CUI: C0019829
Disease: Hodgkin Disease
Hodgkin Disease
0.020 AlteredExpression BEFREE We conclude that the Hp 2 type is associated with elevated s-PAP levels and low plasma nitrite levels in HD patients specifically in the DM state. 26171400

2015

Entrez Id: 55
Gene Symbol: ACP3
ACP3
CUI: C0019829
Disease: Hodgkin Disease
Hodgkin Disease
0.020 Biomarker BEFREE Risk-adjusted analyses demonstrated higher PP (adjusted hazard ratio [aHR], 1.32; 95% confidence interval [CI], 1.20-1.45; P < .001), PAP (aHR, 1.32; 95% CI, 1.19-1.45; P < .001), SP (aHR, 1.47; 95% CI, 1.31-1.65; P < .001), limb salvage (aHR, 1.48; 95% CI, 1.30-1.67; P < .001), and patient survival (aHR, 2.42; 95% CI, 2.17-2.71; P < .001) for RT compared with HD patients. 30583904

2019

Entrez Id: 23205
Gene Symbol: ACSBG1
ACSBG1
CUI: C0019829
Disease: Hodgkin Disease
Hodgkin Disease
0.010 Biomarker BEFREE Forty-three patients showed regression (Reg group), with high rates of Hodgkin lymphoma (HL) and LPD (90 and 88%, respectively). 28877615

2018

Entrez Id: 60
Gene Symbol: ACTB
ACTB
CUI: C0019829
Disease: Hodgkin Disease
Hodgkin Disease
0.020 AlteredExpression BEFREE Confirming the <i>in vitro</i> data, we demonstrated that EVs promote α-SMA expression in fibroblasts and the expression of proangiogenic factors using a xenograft HL model. 29967610

2018

Entrez Id: 60
Gene Symbol: ACTB
ACTB
CUI: C0019829
Disease: Hodgkin Disease
Hodgkin Disease
0.020 AlteredExpression BEFREE In this work, the most reliable housekeeping gene for gene expression analysis of Hodgkin's disease (HD) lymph nodes was determined by comparing the conventional housekeeping genes, beta-actin, beta-tubulin, GAPDH, and the mouse gene LLRep3, that had been used previously in gene expression studies. 1774960

1991