Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 367
Gene Symbol: AR
AR
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		0.600 GeneticVariation UNIPROT

Entrez Id: 367
Gene Symbol: AR
AR
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		0.600 AlteredExpression BEFREE <b>Purpose:</b> Androgen receptor (AR) expression has been observed in about 70% of patients with breast cancer, but its prognostic role remains uncertain.<b>Experimental Design:</b> To assess the prognostic role of AR expression in early-stage breast cancer, we performed a meta-analysis of studies that evaluated the impact of AR at the protein and gene expression level on disease-free survival (DFS) and/or overall survival (OS). 28151718

2017
Entrez Id: 367
Gene Symbol: AR
AR
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		0.600 Biomarker BEFREE <b>Purpose:</b> Steroidal androgens suppress androgen receptor and estrogen receptor positive (AR/ER<sup>+</sup>) breast cancer cells and were used to treat breast cancer, eliciting favorable response. 28974548

2017
Entrez Id: 367
Gene Symbol: AR
AR
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		0.600 GeneticVariation BEFREE Breast cancer susceptibility gene 1 (BRCAI) is a coactivator of the androgen receptor. 11085509

2000
Entrez Id: 367
Gene Symbol: AR
AR
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		0.600 GeneticVariation BEFREE Breast cancer is a rare disease in men.Germ-line mutations in BRCA2 and androgen receptor (AR) genes are thought to be responsible for a proportion of male breast cancer cases. 11139248

2001
Entrez Id: 367
Gene Symbol: AR
AR
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		0.600 Biomarker BEFREE Breast cancer in transgender female-to-male individuals: A case report of androgen receptor-positive breast cancer. 31749246

2019
Entrez Id: 367
Gene Symbol: AR
AR
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		0.600 PosttranslationalModification BEFREE Androgen receptor gene methylation and exon one CAG repeat length in ovarian cancer: differences from breast cancer. 15545219

2004
Entrez Id: 367
Gene Symbol: AR
AR
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		0.600 GeneticVariation BEFREE Androgen receptor gene polymorphisms which render the more transcriptionally active receptors have been related to a lower risk of breast cancer. 17631997

2007
Entrez Id: 367
Gene Symbol: AR
AR
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		0.600 AlteredExpression BEFREE Androgen receptor levels and association with PIK3CA mutations and prognosis in breast cancer. 19276248

2009
Entrez Id: 367
Gene Symbol: AR
AR
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		0.600 Biomarker BEFREE Androgen receptor status predicts response to chemotherapy, not risk of breast cancer in Indian women. 20831839

2010
Entrez Id: 367
Gene Symbol: AR
AR
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		0.600 GeneticVariation BEFREE Androgen receptor gene CAG repeat polymorphism and breast cancer risk in Iranian women: a case-control study. 21159020

2011
Entrez Id: 367
Gene Symbol: AR
AR
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		0.600 AlteredExpression BEFREE Androgen receptor expression in breast cancer patients tested for BRCA1 and BRCA2 mutations. 21166701

2010
Entrez Id: 367
Gene Symbol: AR
AR
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		0.600 AlteredExpression BEFREE Androgen receptor expression is most commonly seen in luminal A and B invasive breast cancers. 21552212

2011
Entrez Id: 367
Gene Symbol: AR
AR
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		0.600 Biomarker BEFREE Androgen receptor (AR) is an attractive target in breast cancer because of its frequent expression in all the molecular subtypes, especially in estrogen receptor (ER)-positive luminal breast cancers. 25178514

2014
Entrez Id: 367
Gene Symbol: AR
AR
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		0.600 AlteredExpression BEFREE Androgen receptor promotes tamoxifen agonist activity by activation of EGFR in ERα-positive breast cancer. 26487496

2015
Entrez Id: 367
Gene Symbol: AR
AR
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		0.600 Biomarker BEFREE Androgen receptor (AR) is involved in the pathogenesis of breast cancer, but its role is not clearly defined. 28067809

2017
Entrez Id: 367
Gene Symbol: AR
AR
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		0.600 Biomarker BEFREE Androgen receptor (AR) is frequently detected in breast cancers, and AR-targeted therapies are showing activity in AR-positive (AR+) breast cancer. 28957377

2017
Entrez Id: 367
Gene Symbol: AR
AR
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		0.600 Biomarker BEFREE Androgen Receptor in Stage I-II Primary Breast Cancer -Prognostic Value and Distribution in Subgroups. 29187464

2017
Entrez Id: 367
Gene Symbol: AR
AR
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		0.600 Biomarker BEFREE Androgen receptor and heat shock protein 27 co-regulate the malignant potential of molecular apocrine breast cancer. 29699584

2018
Entrez Id: 367
Gene Symbol: AR
AR
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		0.600 Biomarker BEFREE Androgen receptor (AR) is closely associated with the occurrence and progression of breast cancer; however, the clinical significance of it in triple negative breast cancer (TNBC) has been controversial. 29844843

2018
Entrez Id: 367
Gene Symbol: AR
AR
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		0.600 AlteredExpression BEFREE Androgen receptor (AR) expression is frequent in breast cancer and has been associated with good prognosis in several studies. 30109519

2018
Entrez Id: 367
Gene Symbol: AR
AR
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		0.600 AlteredExpression BEFREE Androgen receptor expression inversely correlates with immune cell infiltration in human epidermal growth factor receptor 2-positive breast cancer. 30208359

2018
Entrez Id: 367
Gene Symbol: AR
AR
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		0.600 Biomarker BEFREE Androgen receptor (AR) has been extensively studied, but its role in relation to breast cancer patient prognosis remains to be clarified. 31110518

2019
Entrez Id: 367
Gene Symbol: AR
AR
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		0.600 GeneticVariation BEFREE A germline mutation in the androgen receptor gene in two brothers with breast cancer and Reifenstein syndrome. 1303262

1992
Entrez Id: 367
Gene Symbol: AR
AR
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		0.600 Biomarker BEFREE A growing body of literature supports the conclusion that the androgen receptor (AR) plays an important role in breast cancer pathogenesis and may prove to be a relevant therapeutic target for patients with AR-driven breast cancer. 28766215

2017