HLA-DRB1
|
Hepatitis B
|
0.100 |
GeneticVariation |
BEFREE |
Moreover the relation between HLA-DRB1 allelic groups and hepatitis B, hepatitis C and cytomegalovirus viral infections was also studied.
|
24903971 |
2014 |
HLA-DRB1
|
Hepatitis B
|
0.100 |
GeneticVariation |
BEFREE |
In this study, the association between HBV infection and HLA-DRB1 alleles in Han individuals in northwestern China was studied for the first time.
|
17257320 |
2007 |
HLA-DRB1
|
Hepatitis B
|
0.100 |
GeneticVariation |
BEFREE |
The HLA-DRB1*140101 allele may be potentially associated with increased risk of HCC development in CHB patients, irrespective of the replicative activity of hepatitis B virus and antiviral responsiveness.
|
22499074 |
2012 |
HLA-DRB1
|
Hepatitis B
|
0.100 |
GeneticVariation |
LHGDN |
HLA-DRB1*1101 correlates with less severe hepatitis in Taiwanese male carriers of hepatitis B virus.
|
19235869 |
2009 |
HLA-DRB1
|
Hepatitis B
|
0.100 |
GeneticVariation |
BEFREE |
In conclusion, common African HLA-DRB1 and -DQB1 variants, previously associated with protection from malaria and hepatitis B/C virus persistence, predispose the Venda to TB, whereas the proposedly active VDR haplotype F-b-A-T showed significant protection.
|
16916662 |
2006 |
HLA-DRB1
|
Hepatitis B
|
0.100 |
GeneticVariation |
BEFREE |
Characterization and genotyping of the DRB1 gene of the major histocompatibility complex (MHC) in the Marmota monax, animal model of hepatitis B.
|
25458311 |
2015 |
HLA-DRB1
|
Hepatitis B
|
0.100 |
GeneticVariation |
BEFREE |
Beninese origin and HLA-DRB1*09 allele were the other determinants independently associated with favorable outcome of HBV infection.
|
18222012 |
2008 |
HLA-DRB1
|
Hepatitis B
|
0.100 |
GeneticVariation |
BEFREE |
The GWAS identified independent associations of HLA-DRB1-DQB1, HLA-DPB1 and BTNL2 genes with immune response to a HB vaccine designed based on the HBV genotype C. Five HLA-DRB1-DQB1 haplotypes and two DPB1 alleles showed significant associations with response to the HB vaccine in a comparison of three groups of 1,193 HB vaccinated individuals.
|
29534301 |
2018 |
HLA-DRB1
|
Hepatitis B
|
0.100 |
GeneticVariation |
BEFREE |
HLA-DRB and -DQB1 alleles in Polish patients with hepatitis B associated membranous nephropathy.
|
9756401 |
1998 |
HLA-DRB1
|
Hepatitis B
|
0.100 |
GeneticVariation |
BEFREE |
In the second stage (the study of adults), HLA-DRB1*1302 was found in 50 of 195 subjects with transient HBV infection (25.6 percent) and in 3 of 40 subjects with persistent infection (7.5 percent) (relative risk, 0.24; 95 percent confidence interval, 0.04 to 0.80; P = 0.012).
|
7898524 |
1995 |
HLA-DRB1
|
Hepatitis B
|
0.100 |
Biomarker |
BEFREE |
After controlling for pre-booster anti-HBs levels, the absences of HLA-A*02 and -DRB1*08, simply expressed as A*02(-) and -DRB1*08(-), and the presence of B*15 were significantly associated with elevated risks of non-response (post-booster anti-HBs titers<10 mIU/mL) to booster vaccination.
|
18501999 |
2008 |
HLA-DRB1
|
Hepatitis B
|
0.100 |
Biomarker |
LHGDN |
Association of human leukocyte antigen polymorphism with hepatitis B virus infection and genotypes.
|
17186951 |
2006 |
HLA-DRB1
|
Hepatitis B
|
0.100 |
Biomarker |
BEFREE |
The frequency of the allele of HLA-DR12 DRB1*1201 was higher in the subjects recovered from hepatitis B infection (32%) than in the patients with chronic hepatitis B (3%; rr, 0.07; Pcorr<0.005).
|
14599975 |
2003 |
HLA-DRB1
|
Hepatitis B
|
0.100 |
Biomarker |
BEFREE |
Two HLA class II haplotypes, HLA-[DQB1*0602; DQA1*0102; DR15] and HLA-[DQB1*0603; DQA1*0103; DRB1*1301] were found to be less common in 52 nonresponders compared with 68 responders, P<0.025 and P<0.05 respectively, after vaccination with hepatitis B surface antigen (HBsAg).
|
9820601 |
1998 |
HLA-DRB1
|
Hepatitis B
|
0.100 |
Biomarker |
BEFREE |
These data suggest a molecular basis for the differential associations of HLA-DRB1*1301 and DRB1*1302 with resistance to severe malaria and clearance of hepatitis B virus infection.
|
7604034 |
1995 |
HLA-DRB1
|
Hepatitis B
|
0.100 |
Biomarker |
BEFREE |
Although hepatitis B vaccination given during the neonatal period does not increase autoantibody production in 6-year-old immunized children, we deem useful a more prolonged follow-up for these nonresponder children carrying certain HLA haplotypes (such as C4AQ0,DRB1*0301,DQB1*02), particularly because most autoimmune diseases do not develop until later in life.
|
12093985 |
2002 |
HLA-DRB1
|
Hepatitis B
|
0.100 |
Biomarker |
BEFREE |
Eight of 24 patients (33.3%) who cleared hepatitis B virus spontaneously were positive for DRB1*1301-02 (relative risk of developing chronic infection compared to chronic hepatitis B subjects 0.12; p=0.004).
|
9075656 |
1997 |
HLA-DRB1
|
Hepatitis B
|
0.100 |
Biomarker |
BEFREE |
The results revealed that A*02-DRB1*12 and A*02-B*15-DRB1*09 carriers were susceptible to HBV infection.
|
25592155 |
2015 |
HLA-DRB1
|
Hepatitis B
|
0.100 |
Biomarker |
BEFREE |
HLA-B*15, DRB1*11 and 14 associated with viral clearance in the cases of HBV-C2 infection; HLA-B*54 carriers in chronic group are more sensitive to with the infection of HBV subgenotype B2; HLA-B*07 and DRB1*13 may protect subjects from HBV infection.
|
22056847 |
2012 |
HLA-DRB1
|
Hepatitis B
|
0.100 |
Biomarker |
BEFREE |
HLA-DRB1*07, is associated with the susceptibility of the infants to intrauterine HBV infection.
|
18463715 |
2008 |
HLA-DRB1
|
Hepatitis B
|
0.100 |
Biomarker |
BEFREE |
HLA-DRB1*1101 correlates with less severe hepatitis in Taiwanese male carriers of hepatitis B virus.
|
19235869 |
2009 |
HLA-DRB1
|
Hepatitis B
|
0.100 |
Biomarker |
BEFREE |
Genetic variations in STAT4,C2,HLA-DRB1 and HLA-DQ associated with risk of hepatitis B virus-related liver cirrhosis.
|
26538132 |
2015 |
HLA-DRB1
|
Hepatitis B
|
0.100 |
Biomarker |
BEFREE |
HLA-A*33 was closely related with susceptibility to persisting hepatitis B infection, and HLA-DRB1*13 was closely related with protection against persisting hepatitis B in an Iranian population.
|
18761557 |
2008 |
HLA-DRB1
|
Hepatitis B
|
0.100 |
Biomarker |
BEFREE |
The univariate analysis performed revealed significant association of the HLA-DRB1*03 and HLA-DQB1*05 alleles to the infected persons (study group), while HLA-DRB1*01 was shown to be protective against HBV infection.
|
29979894 |
2018 |
HLA-DRB1
|
Hepatitis B
|
0.100 |
Biomarker |
BEFREE |
Compared with other HLA-DRB1 alleles, HLA-DRB1*06, DRB1*08, and DRB1*16 may be associated with chronicity of HBV infection, HLA-DRB1*07 with protection against HBV infection, and HLA-DRB1*14 allele may be associated with a high rate of the response of CHB patients to IFN treatment.
|
16237774 |
2005 |