×
Entrez Id: 6331
Gene Symbol: SCN5A
SCN5A
Brugada Syndrome 1
0.910
GeneticVariation
UNIPROT
Genetic basis and molecular mechanism for idiopathic ventricular fibrillation.
9521325 1998
×
Entrez Id: 6331
Gene Symbol: SCN5A
SCN5A
Brugada Syndrome 1
0.910
GeneticVariation
UNIPROT
Ionic mechanisms responsible for the electrocardiographic phenotype of the Brugada syndrome are temperature dependent.
10532948 1999
×
Entrez Id: 6331
Gene Symbol: SCN5A
SCN5A
Brugada Syndrome 1
0.910
GeneticVariation
UNIPROT
Cardiac Na(+) channel dysfunction in Brugada syndrome is aggravated by beta(1)-subunit.
10618304 2000
×
Entrez Id: 6331
Gene Symbol: SCN5A
SCN5A
Brugada Syndrome 1
0.910
GeneticVariation
UNIPROT
Human SCN5A gene mutations alter cardiac sodium channel kinetics and are associated with the Brugada syndrome.
10690282 1999
×
Entrez Id: 6331
Gene Symbol: SCN5A
SCN5A
Brugada Syndrome 1
0.910
GeneticVariation
UNIPROT
Inherited Brugada and long QT-3 syndrome mutations of a single residue of the cardiac sodium channel confer distinct channel and clinical phenotypes.
11410597 2001
×
Entrez Id: 6331
Gene Symbol: SCN5A
SCN5A
Brugada Syndrome 1
0.910
GeneticVariation
UNIPROT
Novel SCN5A mutation leading either to isolated cardiac conduction defect or Brugada syndrome in a large French family.
11748104 2001
×
Entrez Id: 6331
Gene Symbol: SCN5A
SCN5A
Brugada Syndrome 1
0.910
GeneticVariation
UNIPROT
Genetic and biophysical basis of sudden unexplained nocturnal death syndrome (SUNDS), a disease allelic to Brugada syndrome.
11823453 2002
×
Entrez Id: 6331
Gene Symbol: SCN5A
SCN5A
Brugada Syndrome 1
0.910
GeneticVariation
UNIPROT
Natural history of Brugada syndrome: insights for risk stratification and management.
11901046 2002
×
Entrez Id: 6331
Gene Symbol: SCN5A
SCN5A
Brugada Syndrome 1
0.910
GeneticVariation
UNIPROT
Novel mutations in domain I of SCN5A cause Brugada syndrome.
12051963 2002
×
Entrez Id: 6331
Gene Symbol: SCN5A
SCN5A
Brugada Syndrome 1
0.910
GeneticVariation
UNIPROT
Genotype-phenotype relationship in Brugada syndrome: electrocardiographic features differentiate SCN5A-related patients from non-SCN5A-related patients.
12106943 2002
×
Entrez Id: 6331
Gene Symbol: SCN5A
SCN5A
Brugada Syndrome 1
0.910
GeneticVariation
UNIPROT
A trafficking defective, Brugada syndrome-causing SCN5A mutation rescued by drugs.
15023552 2004
×
Entrez Id: 6331
Gene Symbol: SCN5A
SCN5A
Brugada Syndrome 1
0.910
GeneticVariation
UNIPROT
Genetic analysis of the cardiac sodium channel gene SCN5A in Koreans with Brugada syndrome.
15338453 2004
×
Entrez Id: 6331
Gene Symbol: SCN5A
SCN5A
Brugada Syndrome 1
0.910
GeneticVariation
UNIPROT
Nav1.5 E1053K mutation causing Brugada syndrome blocks binding to ankyrin-G and expression of Nav1.5 on the surface of cardiomyocytes.
15579534 2004
×
Entrez Id: 6331
Gene Symbol: SCN5A
SCN5A
Brugada Syndrome 1
0.910
GeneticVariation
UNIPROT
Double SCN5A mutation underlying asymptomatic Brugada syndrome.
15851320 2005
×
Entrez Id: 6331
Gene Symbol: SCN5A
SCN5A
Brugada Syndrome 1
0.910
GeneticVariation
UNIPROT
Novel Brugada syndrome-causing mutation in ion-conducting pore of cardiac Na+ channel does not affect ion selectivity properties.
16266370 2005
×
Entrez Id: 6331
Gene Symbol: SCN5A
SCN5A
Brugada Syndrome 1
0.910
GeneticVariation
UNIPROT
High risk for bradyarrhythmic complications in patients with Brugada syndrome caused by SCN5A gene mutations.
16325048 2005
×
Entrez Id: 6331
Gene Symbol: SCN5A
SCN5A
Brugada Syndrome 1
0.910
GeneticVariation
UNIPROT
A novel SCN5A mutation, F1344S, identified in a patient with Brugada syndrome and fever-induced ventricular fibrillation.
16616735 2006
×
Entrez Id: 6331
Gene Symbol: SCN5A
SCN5A
Brugada Syndrome 1
0.910
GeneticVariation
UNIPROT
Compound heterozygous mutations P336L and I1660V in the human cardiac sodium channel associated with the Brugada syndrome.
17075016 2006
×
Entrez Id: 6331
Gene Symbol: SCN5A
SCN5A
Brugada Syndrome 1
0.910
GeneticVariation
UNIPROT
[Novel SCN5A gene mutations associated with Brugada syndrome: V95I, A1649V and delF1617].
17081365 2006
×
Entrez Id: 6331
Gene Symbol: SCN5A
SCN5A
Brugada Syndrome 1
0.910
GeneticVariation
UNIPROT
A sodium channel pore mutation causing Brugada syndrome.
17198989 2007
×
Entrez Id: 6331
Gene Symbol: SCN5A
SCN5A
Brugada Syndrome 1
0.910
GeneticVariation
UNIPROT
Analyses of a novel SCN5A mutation (C1850S): conduction vs. repolarization disorder hypotheses in the Brugada syndrome.
18252757 2008
×
Entrez Id: 6331
Gene Symbol: SCN5A
SCN5A
Brugada Syndrome 1
0.910
GeneticVariation
UNIPROT
[Gene (SCN5A) mutation analysis of a Chinese family with Brugada syndrome].
18341814 2007
×
Entrez Id: 6331
Gene Symbol: SCN5A
SCN5A
Brugada Syndrome 1
0.910
GeneticVariation
UNIPROT
The E1784K mutation in SCN5A is associated with mixed clinical phenotype of type 3 long QT syndrome.
18451998 2008
×
Entrez Id: 6331
Gene Symbol: SCN5A
SCN5A
Brugada Syndrome 1
0.910
GeneticVariation
UNIPROT
Subepicardial phase 0 block and discontinuous transmural conduction underlie right precordial ST-segment elevation by a SCN5A loss-of-function mutation.
18456723 2008
×
Entrez Id: 6331
Gene Symbol: SCN5A
SCN5A
Brugada Syndrome 1
0.910
GeneticVariation
UNIPROT
Correlations between clinical and physiological consequences of the novel mutation R878C in a highly conserved pore residue in the cardiac Na+ channel.
18616619 2008