Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 324
Gene Symbol: APC
APC
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.200 GeneticVariation CLINVAR Prospective enterprise-level molecular genotyping of a cohort of cancer patients. 25157968

2014

Entrez Id: 472
Gene Symbol: ATM
ATM
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.500 CausalMutation CLINVAR

Entrez Id: 673
Gene Symbol: BRAF
BRAF
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.200 GeneticVariation CLINVAR Prospective enterprise-level molecular genotyping of a cohort of cancer patients. 25157968

2014

Entrez Id: 673
Gene Symbol: BRAF
BRAF
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.200 GeneticVariation CLINVAR Mechanism of activation of the RAF-ERK signaling pathway by oncogenic mutations of B-RAF. 15035987

2004

Entrez Id: 100270680
Gene Symbol: CASC11
CASC11
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.140 GeneticVariation CLINVAR Prospective enterprise-level molecular genotyping of a cohort of cancer patients. 25157968

2014

Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.500 GeneticVariation CLINVAR Prospective enterprise-level molecular genotyping of a cohort of cancer patients. 25157968

2014

Entrez Id: 1436
Gene Symbol: CSF1R
CSF1R
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.500 GeneticVariation CLINVAR Prospective enterprise-level molecular genotyping of a cohort of cancer patients. 25157968

2014

Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.200 GeneticVariation CLINVAR Prospective enterprise-level molecular genotyping of a cohort of cancer patients. 25157968

2014

Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.200 GeneticVariation CLINVAR Prospective enterprise-level molecular genotyping of a cohort of cancer patients. 25157968

2014

Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.200 GeneticVariation CLINVAR Functional analysis of receptor tyrosine kinase mutations in lung cancer identifies oncogenic extracellular domain mutations of ERBB2. 22908275

2012

Entrez Id: 2065
Gene Symbol: ERBB3
ERBB3
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.200 GeneticVariation CLINVAR Oncogenic ERBB3 mutations in human cancers. 23680147

2013

Entrez Id: 2260
Gene Symbol: FGFR1
FGFR1
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.200 GeneticVariation CLINVAR Prospective enterprise-level molecular genotyping of a cohort of cancer patients. 25157968

2014

Entrez Id: 2778
Gene Symbol: GNAS
GNAS
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.200 GeneticVariation CLINVAR Prospective enterprise-level molecular genotyping of a cohort of cancer patients. 25157968

2014

Entrez Id: 2778
Gene Symbol: GNAS
GNAS
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.200 GeneticVariation CLINVAR GNAS-activating mutations define a rare subgroup of inflammatory liver tumors characterized by STAT3 activation. 21835143

2012

Entrez Id: 3265
Gene Symbol: HRAS
HRAS
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.200 GeneticVariation CLINVAR Prospective enterprise-level molecular genotyping of a cohort of cancer patients. 25157968

2014

Entrez Id: 5604
Gene Symbol: MAP2K1
MAP2K1
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.200 GeneticVariation CLINVAR Discovery of a novel ERK inhibitor with activity in models of acquired resistance to BRAF and MEK inhibitors. 23614898

2013

Entrez Id: 5604
Gene Symbol: MAP2K1
MAP2K1
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.200 GeneticVariation CLINVAR MEK1 mutations confer resistance to MEK and B-RAF inhibition. 19915144

2009

Entrez Id: 4609
Gene Symbol: MYC
MYC
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.500 GeneticVariation CLINVAR Prospective enterprise-level molecular genotyping of a cohort of cancer patients. 25157968

2014

Entrez Id: 4893
Gene Symbol: NRAS
NRAS
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.200 GeneticVariation CLINVAR Prospective enterprise-level molecular genotyping of a cohort of cancer patients. 25157968

2014

Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.200 GeneticVariation CLINVAR Prospective enterprise-level molecular genotyping of a cohort of cancer patients. 25157968

2014

Entrez Id: 5295
Gene Symbol: PIK3R1
PIK3R1
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.200 GeneticVariation CLINVAR The structural basis of PI3K cancer mutations: from mechanism to therapy. 24459181

2014

Entrez Id: 5295
Gene Symbol: PIK3R1
PIK3R1
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.200 GeneticVariation CLINVAR Prospective enterprise-level molecular genotyping of a cohort of cancer patients. 25157968

2014

Entrez Id: 5295
Gene Symbol: PIK3R1
PIK3R1
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.200 GeneticVariation CLINVAR Somatic mutations in PI3Kalpha: structural basis for enzyme activation and drug design. 19962457

2010

Entrez Id: 5728
Gene Symbol: PTEN
PTEN
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.200 GeneticVariation CLINVAR Prospective enterprise-level molecular genotyping of a cohort of cancer patients. 25157968

2014

Entrez Id: 5925
Gene Symbol: RB1
RB1
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.200 GeneticVariation CLINVAR Prospective enterprise-level molecular genotyping of a cohort of cancer patients. 25157968

2014