×
Entrez Id: 4878
Gene Symbol: NPPA
NPPA
Hypertensive disease
0.600
Biomarker
MGD
×
Entrez Id: 4878
Gene Symbol: NPPA
NPPA
Hypertensive disease
0.600
Therapeutic
CTD_human
Severe proteinuria without impairment of sodium and volume excretion after puromycin aminonucleoside administration in rats.
2526952 1989
×
Entrez Id: 4878
Gene Symbol: NPPA
NPPA
Hypertensive disease
0.600
Biomarker
CTD_human
Severe proteinuria without impairment of sodium and volume excretion after puromycin aminonucleoside administration in rats.
2526952 1989
×
Entrez Id: 4878
Gene Symbol: NPPA
NPPA
Hypertensive disease
0.600
Biomarker
CTD_human
Central cardiovascular effects of AVP and ANP in normotensive and spontaneously hypertensive rats.
8188982 1994
×
Entrez Id: 4878
Gene Symbol: NPPA
NPPA
Hypertensive disease
0.600
Therapeutic
CTD_human
Central cardiovascular effects of AVP and ANP in normotensive and spontaneously hypertensive rats.
8188982 1994
×
Entrez Id: 4878
Gene Symbol: NPPA
NPPA
Hypertensive disease
0.600
Biomarker
CTD_human
Genetic decreases in atrial natriuretic peptide and salt-sensitive hypertension.
7839143 1995
×
Entrez Id: 4878
Gene Symbol: NPPA
NPPA
Hypertensive disease
0.600
Therapeutic
CTD_human
Genetic decreases in atrial natriuretic peptide and salt-sensitive hypertension.
7839143 1995
×
Entrez Id: 4878
Gene Symbol: NPPA
NPPA
Hypertensive disease
0.600
Biomarker
BEFREE
This suggests that: 1) this I/D dimorphism is not a useful marker to study the relationship between the ANF gene and hypertension in the UAE; and 2) variations of the ANF gene that may be in linkage disequilibrium with this marker do not play a major role in the determination of hypertension in this Arab population.
9397252 1997
×
Entrez Id: 4878
Gene Symbol: NPPA
NPPA
Hypertensive disease
0.600
GeneticVariation
BEFREE
Since diabetic nephropathy and hypertension are closely related, ANP is a reasonable candidate gene for diabetic nephropathy (DN).
9681733 1998
×
Entrez Id: 4878
Gene Symbol: NPPA
NPPA
Hypertensive disease
0.600
Biomarker
CTD_human
Dissociation of blood pressure reduction from end-organ damage in TGR(mREN2)27 transgenic hypertensive rats.
9869009 1998
×
Entrez Id: 4878
Gene Symbol: NPPA
NPPA
Hypertensive disease
0.600
Therapeutic
CTD_human
Dissociation of blood pressure reduction from end-organ damage in TGR(mREN2)27 transgenic hypertensive rats.
9869009 1998
×
Entrez Id: 4878
Gene Symbol: NPPA
NPPA
Hypertensive disease
0.600
Biomarker
BEFREE
Our previous studies have shown that ANP gene delivery attenuates hypertension , cardiac hypertrophy, and renal injury in Dahl salt-sensitive (Dahl-SS) rats.
9931108 1999
×
Entrez Id: 4878
Gene Symbol: NPPA
NPPA
Hypertensive disease
0.600
Biomarker
CTD_human
Neutralization of proANP (1-30) exacerbates hypertension in the spontaneously hypertensive rat.
12940879 2003
×
Entrez Id: 4878
Gene Symbol: NPPA
NPPA
Hypertensive disease
0.600
Therapeutic
CTD_human
Neutralization of proANP (1-30) exacerbates hypertension in the spontaneously hypertensive rat.
12940879 2003
×
Entrez Id: 4878
Gene Symbol: NPPA
NPPA
Hypertensive disease
0.600
Biomarker
BEFREE
The ANP gene, which encodes the precursor of atrial natriuretic peptide (ANP), is among the candidate genes for genetic susceptibility to hypertension .
16368448 2005
×
Entrez Id: 4878
Gene Symbol: NPPA
NPPA
Hypertensive disease
0.600
Biomarker
LHGDN
Association of atrial natriuretic peptide and type a natriuretic peptide receptor gene polymorphisms with left ventricular mass in human essential hypertension.
16875975 2006
×
Entrez Id: 4878
Gene Symbol: NPPA
NPPA
Hypertensive disease
0.600
GeneticVariation
LHGDN
In this cohort, the ANP gene variant was associated with early blood pressure increase and predisposition to develop hypertension .
17525707 2007
×
Entrez Id: 4878
Gene Symbol: NPPA
NPPA
Hypertensive disease
0.600
Biomarker
BEFREE
If corroborated by other large-scale, prospective studies, our findings indicate that the natriuretic peptide precursor A gene plays a significant role in blood pressure regulation and development of hypertension .
17984371 2007
×
Entrez Id: 4878
Gene Symbol: NPPA
NPPA
Hypertensive disease
0.600
GeneticVariation
BEFREE
In this cohort, the ANP gene variant was associated with early blood pressure increase and predisposition to develop hypertension .
17525707 2007
×
Entrez Id: 4878
Gene Symbol: NPPA
NPPA
Hypertensive disease
0.600
Biomarker
LHGDN
If corroborated by other large-scale, prospective studies, our findings indicate that the natriuretic peptide precursor A gene plays a significant role in blood pressure regulation and development of hypertension .
17984371 2007
×
Entrez Id: 4878
Gene Symbol: NPPA
NPPA
Hypertensive disease
0.600
Biomarker
LHGDN
The concentration of atrial and brain natriuretic peptide in patients with idiopathic hypertension.
17901852 2007
×
Entrez Id: 4878
Gene Symbol: NPPA
NPPA
Hypertensive disease
0.600
GeneticVariation
LHGDN
In conclusion, our findings indicate that the -A2843G polymorphism in the ANP gene promoter might be a genetic risk factor for the development of LVH in patients with hypertension .
17672826 2008
×
Entrez Id: 4878
Gene Symbol: NPPA
NPPA
Hypertensive disease
0.600
GeneticVariation
BEFREE
In conclusion, our findings indicate that the -A2843G polymorphism in the ANP gene promoter might be a genetic risk factor for the development of LVH in patients with hypertension .
17672826 2008
×
Entrez Id: 4878
Gene Symbol: NPPA
NPPA
Hypertensive disease
0.600
GeneticVariation
BEFREE
Pharmacogenetic association of the NPPA T2238C genetic variant with cardiovascular disease outcomes in patients with hypertension .
18212314 2008
×
Entrez Id: 4878
Gene Symbol: NPPA
NPPA
Hypertensive disease
0.600
GeneticVariation
BEFREE
NPPA gene polymorphisms may have a role in BP progression and incident hypertension .19330901 2009