Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.600 Biomarker MGD

Entrez Id: 5728
Gene Symbol: PTEN
PTEN
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.600 Biomarker MGD

Entrez Id: 7048
Gene Symbol: TGFBR2
TGFBR2
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.540 Biomarker MGD

Entrez Id: 324
Gene Symbol: APC
APC
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.520 Biomarker MGD

Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.500 Biomarker MGD

Entrez Id: 1316
Gene Symbol: KLF6
KLF6
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.400 Biomarker CTD_human

Entrez Id: 4601
Gene Symbol: MXI1
MXI1
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.360 Biomarker CTD_human

Entrez Id: 10664
Gene Symbol: CTCF
CTCF
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.310 GeneticVariation UNIPROT

Entrez Id: 8379
Gene Symbol: MAD1L1
MAD1L1
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.300 Biomarker CTD_human

Entrez Id: 168002
Gene Symbol: DACT2
DACT2
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.010 Biomarker BEFREE <b>Conclusions</b>: Our study provides evidence that DACT-2 may be a useful biomarker for distinguishing prostate tumor tissues from non-cancerous samples and a potential target for epigenetic silencing in primary prostate Cancer. 31205531

2019

Entrez Id: 2919
Gene Symbol: CXCL1
CXCL1
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.010 Biomarker BEFREE <b>Principal conclusions</b>: Taken together, our results argue that CXCL1 plays an important role in sustaining the growth of bladder and prostate tumors via up-regulation of IL6 and down-regulation of TIMP4. 30809313

2019

Entrez Id: 3569
Gene Symbol: IL6
IL6
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.400 AlteredExpression BEFREE <b>Principal conclusions</b>: Taken together, our results argue that CXCL1 plays an important role in sustaining the growth of bladder and prostate tumors via up-regulation of IL6 and down-regulation of TIMP4. 30809313

2019

Entrez Id: 7079
Gene Symbol: TIMP4
TIMP4
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.320 AlteredExpression BEFREE <b>Principal conclusions</b>: Taken together, our results argue that CXCL1 plays an important role in sustaining the growth of bladder and prostate tumors via up-regulation of IL6 and down-regulation of TIMP4. 30809313

2019

Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.400 GeneticVariation LHGDN -160C/A polymorphism in the E-cadherin gene promoter and risk of hereditary, familial and sporadic prostate cancer. 14961571

2004

Entrez Id: 247
Gene Symbol: ALOX15B
ALOX15B
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.030 AlteredExpression LHGDN 15-Lipoxygenase-2 gene regulation by its product 15-(S)-hydroxyeicosatetraenoic acid through a negative feedback mechanism that involves peroxisome proliferator-activated receptor gamma. 16682954

2006

Entrez Id: 2346
Gene Symbol: FOLH1
FOLH1
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.400 Biomarker BEFREE 18F-FDG, 68Ga-DOTATATE and 68Ga-PSMA Positive Metastatic Large Cell Neuroendocrine Prostate Tumor. 30325820

2019

Entrez Id: 2922
Gene Symbol: GRP
GRP
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.020 Biomarker BEFREE 18F-labeled bombesin analog for specific and effective targeting of prostate tumors expressing gastrin-releasing peptide receptors. 21233180

2011

Entrez Id: 2346
Gene Symbol: FOLH1
FOLH1
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.400 Biomarker CTD_human 1alpha,25-Dihydroxyvitamin D3 down-regulates expression of prostate specific membrane antigen in prostate cancer cells. 18247401

2008

Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.060 Biomarker BEFREE 2-Methoxyestradiol inhibits prostate tumor development in transgenic adenocarcinoma of mouse prostate: role of tumor necrosis factor-alpha-stimulated gene 6. 16467113

2006

Entrez Id: 4092
Gene Symbol: SMAD7
SMAD7
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.010 AlteredExpression LHGDN 2-Methoxyestradiol-induced apoptosis in prostate cancer cells requires Smad7. 15708859

2005

Entrez Id: 367
Gene Symbol: AR
AR
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.600 Biomarker BEFREE 20(S)-protopanaxadiol regio-selectively targets androgen receptor: anticancer effects in castration-resistant prostate tumors. 29765513

2018

Entrez Id: 1594
Gene Symbol: CYP27B1
CYP27B1
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.050 AlteredExpression LHGDN 25-Hydroxyvitamin D-1alpha-hydroxylase activity is diminished in human prostate cancer cells and is enhanced by gene transfer. 12137802

2002

Entrez Id: 367
Gene Symbol: AR
AR
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.600 Biomarker BEFREE 4-(Anilino)pyrrole-2-carboxamides: Novel non-steroidal/non-anilide type androgen antagonists effective upon human prostate tumor LNCaP cells with mutated nuclear androgen receptor. 18571420

2008

Entrez Id: 6041
Gene Symbol: RNASEL
RNASEL
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.400 GeneticVariation BEFREE 589 prostate tumor samples were genotyped by real-time PCR with regard to the RNaseL mutation. 19835577

2009

Entrez Id: 6716
Gene Symbol: SRD5A2
SRD5A2
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.400 GeneticVariation LHGDN 5alpha-reductase 2 polymorphisms as risk factors in prostate cancer. 12042668

2002