×
Entrez Id: 6794
Gene Symbol: STK11
STK11
Neoplastic Syndromes, Hereditary
0.120
GeneticVariation
CLINVAR
Further observations on LKB1/STK11 status and cancer risk in Peutz-Jeghers syndrome.
12865922 2003
×
Entrez Id: 6794
Gene Symbol: STK11
STK11
Neoplastic Syndromes, Hereditary
0.120
GeneticVariation
BEFREE
LKB1 is a serine-threonine protein kinase mutated in patients with an autosomal dominantly inherited cancer syndrome predisposing to multiple benign and malignant tumours, termed Peutz-Jeghers syndrome.12829253 2003
×
Entrez Id: 6794
Gene Symbol: STK11
STK11
Neoplastic Syndromes, Hereditary
0.120
GeneticVariation
CLINVAR
An unusual case of sex cord tumor with annular tubules with malignant transformation in a patient with Peutz-Jeghers syndrome.
19952941 2010
×
Entrez Id: 6794
Gene Symbol: STK11
STK11
Neoplastic Syndromes, Hereditary
0.120
GeneticVariation
CLINVAR
High prevalence of germline STK11 mutations in Hungarian Peutz-Jeghers Syndrome patients.
21118512 2010
×
Entrez Id: 6794
Gene Symbol: STK11
STK11
Neoplastic Syndromes, Hereditary
0.120
GeneticVariation
BEFREE
Peutz-Jeghers Syndrome (PJS) is a hereditary cancer predisposing syndrome caused by autosomal dominant mutations in the serine/threonine kinase 11 (STK11 ) gene and is associated with decreased life expectancy.
29720104 2018
×
Entrez Id: 6794
Gene Symbol: STK11
STK11
Neoplastic Syndromes, Hereditary
0.120
GeneticVariation
CLINVAR
Structure of the LKB1-STRAD-MO25 complex reveals an allosteric mechanism of kinase activation.
19892943 2009
×
Entrez Id: 6794
Gene Symbol: STK11
STK11
Neoplastic Syndromes, Hereditary
0.120
GeneticVariation
CLINVAR
Cancer risks in LKB1 germline mutation carriers.
16407375 2006
×
Entrez Id: 6794
Gene Symbol: STK11
STK11
Neoplastic Syndromes, Hereditary
0.120
GeneticVariation
CLINVAR
STK11 genotyping and cancer risk in Peutz-Jeghers syndrome.
15863673 2005
×
Entrez Id: 6794
Gene Symbol: STK11
STK11
Neoplastic Syndromes, Hereditary
0.120
GeneticVariation
CLINVAR
Frequency and spectrum of cancers in the Peutz-Jeghers syndrome.
16707622 2006
×
Entrez Id: 6794
Gene Symbol: STK11
STK11
Neoplastic Syndromes, Hereditary
0.120
GeneticVariation
CLINVAR
Peutz-Jeghers families unlinked to STK11/LKB1 gene mutations are highly predisposed to primitive biliary adenocarcinoma.
11389158 2001
×
Entrez Id: 6794
Gene Symbol: STK11
STK11
Neoplastic Syndromes, Hereditary
0.120
GeneticVariation
CLINVAR
Relative frequency and morphology of cancers in STK11 mutation carriers.
15188174 2004
×
Entrez Id: 6794
Gene Symbol: STK11
STK11
Neoplastic Syndromes, Hereditary
0.120
GeneticVariation
CLINVAR
Predicting the functional effect of amino acid substitutions and indels.
23056405 2012
×
Entrez Id: 6794
Gene Symbol: STK11
STK11
Neoplastic Syndromes, Hereditary
0.120
GeneticVariation
CLINVAR
Mutations and impaired function of LKB1 in familial and non-familial Peutz-Jeghers syndrome and a sporadic testicular cancer.
9887330 1999
×
Entrez Id: 6794
Gene Symbol: STK11
STK11
Neoplastic Syndromes, Hereditary
0.120
GeneticVariation
CLINVAR
High Resolution Melting analysis as a rapid and efficient method of screening for small mutations in the STK11 gene in patients with Peutz-Jeghers syndrome.
23718779 2013
×
Entrez Id: 6794
Gene Symbol: STK11
STK11
Neoplastic Syndromes, Hereditary
0.120
GeneticVariation
CLINVAR
An updated mutation spectrum in an Australian series of PJS patients provides further evidence for only one gene locus.
17026623 2006
×
Entrez Id: 6794
Gene Symbol: STK11
STK11
Neoplastic Syndromes, Hereditary
0.120
GeneticVariation
CLINVAR
Novel mutations in the LKB1/STK11 gene in Dutch Peutz-Jeghers families.
10408777 1999
×
Entrez Id: 6794
Gene Symbol: STK11
STK11
Neoplastic Syndromes, Hereditary
0.120
GeneticVariation
CLINVAR
Cancer risk associated with STK11/LKB1 germline mutations in Peutz-Jeghers syndrome patients: results of an Italian multicenter study.
23415580 2013
×
Entrez Id: 6794
Gene Symbol: STK11
STK11
Neoplastic Syndromes, Hereditary
0.120
GeneticVariation
CLINVAR
STK11 domain XI mutations: candidate genetic drivers leading to the development of dysplastic polyps in Peutz-Jeghers syndrome.
24652667 2014
×
Entrez Id: 6794
Gene Symbol: STK11
STK11
Neoplastic Syndromes, Hereditary
0.120
GeneticVariation
CLINVAR
Morphology-dependent resonances in a large dielectric sphere: An asymptotic calculation using local coordinates.
9908348 1992
×
Entrez Id: 6794
Gene Symbol: STK11
STK11
Neoplastic Syndromes, Hereditary
0.120
GeneticVariation
CLINVAR
SIRT1 modulation of the acetylation status, cytosolic localization, and activity of LKB1. Possible role in AMP-activated protein kinase activation.
18687677 2008
×
Entrez Id: 6794
Gene Symbol: STK11
STK11
Neoplastic Syndromes, Hereditary
0.120
GeneticVariation
CLINVAR
Novel mutations in the STK11 gene in Thai patients with Peutz-Jeghers syndrome.
19908348 2009
×
Entrez Id: 6794
Gene Symbol: STK11
STK11
Neoplastic Syndromes, Hereditary
0.120
GeneticVariation
CLINVAR
Prevalence of germline PTEN, BMPR1A, SMAD4, STK11, and ENG mutations in patients with moderate-load colorectal polyps.
23399955 2013
×
Entrez Id: 6794
Gene Symbol: STK11
STK11
Neoplastic Syndromes, Hereditary
0.120
GeneticVariation
CLINVAR
A serine/threonine kinase gene defective in Peutz-Jeghers syndrome.
9428765 1998
×
Entrez Id: 6794
Gene Symbol: STK11
STK11
Neoplastic Syndromes, Hereditary
0.120
GeneticVariation
CLINVAR
Exonic STK11 deletions are not a rare cause of Peutz-Jeghers syndrome.
16582077 2006
×
Entrez Id: 6794
Gene Symbol: STK11
STK11
Neoplastic Syndromes, Hereditary
0.120
GeneticVariation
CLINVAR
Genetic and Clinical Analyses of Southern Chinese Children with Peutz-Jeghers Syndrome.
26225618 2015