|
| Entrez Id: |
1029 |
| Gene Symbol: |
CDKN2A |
CDKN2A
|
MELANOMA-PANCREATIC CANCER SYNDROME
|
0.600 |
Biomarker |
CTD_human |
|
|
|
|
| Entrez Id: |
1029 |
| Gene Symbol: |
CDKN2A |
CDKN2A
|
MELANOMA-PANCREATIC CANCER SYNDROME
|
0.600 |
CausalMutation |
CLINVAR |
Germline p16 mutations in familial melanoma.
|
7987387 |
1994 |
|
| Entrez Id: |
1029 |
| Gene Symbol: |
CDKN2A |
CDKN2A
|
MELANOMA-PANCREATIC CANCER SYNDROME
|
0.600 |
CausalMutation |
CLINVAR |
Analysis of the p16 gene (CDKN2) as a candidate for the chromosome 9p melanoma susceptibility locus.
|
7987388 |
1994 |
|
| Entrez Id: |
1029 |
| Gene Symbol: |
CDKN2A |
CDKN2A
|
MELANOMA-PANCREATIC CANCER SYNDROME
|
0.600 |
Biomarker |
CLINGEN |
Homozygotes for CDKN2 (p16) germline mutation in Dutch familial melanoma kindreds.
|
7670475 |
1995 |
|
| Entrez Id: |
1029 |
| Gene Symbol: |
CDKN2A |
CDKN2A
|
MELANOMA-PANCREATIC CANCER SYNDROME
|
0.600 |
Biomarker |
CLINGEN |
A p16INK4a-insensitive CDK4 mutant targeted by cytolytic T lymphocytes in a human melanoma.
|
7652577 |
1995 |
|
| Entrez Id: |
1029 |
| Gene Symbol: |
CDKN2A |
CDKN2A
|
MELANOMA-PANCREATIC CANCER SYNDROME
|
0.600 |
CausalMutation |
CLINVAR |
Mutations associated with familial melanoma impair p16INK4 function.
|
7647780 |
1995 |
|
| Entrez Id: |
1029 |
| Gene Symbol: |
CDKN2A |
CDKN2A
|
MELANOMA-PANCREATIC CANCER SYNDROME
|
0.600 |
Biomarker |
CLINGEN |
Brief report: a familial syndrome of pancreatic cancer and melanoma with a mutation in the CDKN2 tumor-suppressor gene.
|
7666917 |
1995 |
|
| Entrez Id: |
1029 |
| Gene Symbol: |
CDKN2A |
CDKN2A
|
MELANOMA-PANCREATIC CANCER SYNDROME
|
0.600 |
CausalMutation |
CLINVAR |
Prevalence of germ-line mutations in p16, p19ARF, and CDK4 in familial melanoma: analysis of a clinic-based population.
|
8710906 |
1996 |
|
| Entrez Id: |
1029 |
| Gene Symbol: |
CDKN2A |
CDKN2A
|
MELANOMA-PANCREATIC CANCER SYNDROME
|
0.600 |
Biomarker |
CLINGEN |
Novel germline p16 mutation in familial malignant melanoma in southern Sweden.
|
8653684 |
1996 |
|
| Entrez Id: |
1029 |
| Gene Symbol: |
CDKN2A |
CDKN2A
|
MELANOMA-PANCREATIC CANCER SYNDROME
|
0.600 |
GeneticVariation |
CLINVAR |
Novel germline p16(INK4) allele (Asp145Cys) in a family with multiple pancreatic carcinomas. Mutations in brief no. 148. Online.
|
10627132 |
1998 |
|
| Entrez Id: |
1029 |
| Gene Symbol: |
CDKN2A |
CDKN2A
|
MELANOMA-PANCREATIC CANCER SYNDROME
|
0.600 |
GeneticVariation |
CLINVAR |
Prevalence of p16 and CDK4 germline mutations in 48 melanoma-prone families in France. The French Familial Melanoma Study Group.
|
9425228 |
1998 |
|
| Entrez Id: |
1029 |
| Gene Symbol: |
CDKN2A |
CDKN2A
|
MELANOMA-PANCREATIC CANCER SYNDROME
|
0.600 |
Biomarker |
CLINGEN |
Haplotype analysis of two recurrent CDKN2A mutations in 10 melanoma families: evidence for common founders and independent mutations.
|
9603434 |
1998 |
|
| Entrez Id: |
1029 |
| Gene Symbol: |
CDKN2A |
CDKN2A
|
MELANOMA-PANCREATIC CANCER SYNDROME
|
0.600 |
GeneticVariation |
CLINVAR |
CDKN2A mutations in multiple primary melanomas.
|
9516223 |
1998 |
|
| Entrez Id: |
1029 |
| Gene Symbol: |
CDKN2A |
CDKN2A
|
MELANOMA-PANCREATIC CANCER SYNDROME
|
0.600 |
GeneticVariation |
CLINVAR |
CDKN2A germline mutations in U.K. patients with familial melanoma and multiple primary melanomas.
|
9699728 |
1998 |
|
| Entrez Id: |
1029 |
| Gene Symbol: |
CDKN2A |
CDKN2A
|
MELANOMA-PANCREATIC CANCER SYNDROME
|
0.600 |
CausalMutation |
CLINVAR |
Functional reassessment of P16 variants using a transfection-based assay.
|
10389768 |
1999 |
|
| Entrez Id: |
1029 |
| Gene Symbol: |
CDKN2A |
CDKN2A
|
MELANOMA-PANCREATIC CANCER SYNDROME
|
0.600 |
CausalMutation |
CLINVAR |
Mutation of the CDKN2A 5' UTR creates an aberrant initiation codon and predisposes to melanoma.
|
9916806 |
1999 |
|
| Entrez Id: |
1029 |
| Gene Symbol: |
CDKN2A |
CDKN2A
|
MELANOMA-PANCREATIC CANCER SYNDROME
|
0.600 |
CausalMutation |
CLINVAR |
A single genetic origin for the G101W CDKN2A mutation in 20 melanoma-prone families.
|
10869234 |
2000 |
|
| Entrez Id: |
1029 |
| Gene Symbol: |
CDKN2A |
CDKN2A
|
MELANOMA-PANCREATIC CANCER SYNDROME
|
0.600 |
Biomarker |
CLINGEN |
Loss of p16Ink4a confers susceptibility to metastatic melanoma in mice.
|
11544530 |
2001 |
|
| Entrez Id: |
1029 |
| Gene Symbol: |
CDKN2A |
CDKN2A
|
MELANOMA-PANCREATIC CANCER SYNDROME
|
0.600 |
GeneticVariation |
CLINVAR |
CDKN2A and CDK4 mutation analysis in Italian melanoma-prone families: functional characterization of a novel CDKN2A germ line mutation.
|
11556834 |
2001 |
|
| Entrez Id: |
1029 |
| Gene Symbol: |
CDKN2A |
CDKN2A
|
MELANOMA-PANCREATIC CANCER SYNDROME
|
0.600 |
CausalMutation |
CLINVAR |
Geographical variation in the penetrance of CDKN2A mutations for melanoma.
|
12072543 |
2002 |
|
| Entrez Id: |
1029 |
| Gene Symbol: |
CDKN2A |
CDKN2A
|
MELANOMA-PANCREATIC CANCER SYNDROME
|
0.600 |
GeneticVariation |
CLINVAR |
Phenotypic variation in eight extended CDKN2A germline mutation familial atypical multiple mole melanoma-pancreatic carcinoma-prone families: the familial atypical mole melanoma-pancreatic carcinoma syndrome.
|
11815963 |
2002 |
|
| Entrez Id: |
1029 |
| Gene Symbol: |
CDKN2A |
CDKN2A
|
MELANOMA-PANCREATIC CANCER SYNDROME
|
0.600 |
GeneticVariation |
CLINVAR |
Germline splicing mutations of CDKN2A predispose to melanoma.
|
14508519 |
2003 |
|
| Entrez Id: |
1029 |
| Gene Symbol: |
CDKN2A |
CDKN2A
|
MELANOMA-PANCREATIC CANCER SYNDROME
|
0.600 |
GeneticVariation |
CLINVAR |
A single Mediterranean, possibly Jewish, origin for the Val59Gly CDKN2A mutation in four melanoma-prone families.
|
12700603 |
2003 |
|
| Entrez Id: |
1029 |
| Gene Symbol: |
CDKN2A |
CDKN2A
|
MELANOMA-PANCREATIC CANCER SYNDROME
|
0.600 |
GeneticVariation |
CLINVAR |
CDKN2A point mutations D153spl(c.457G>T) and IVS2+1G>T result in aberrant splice products affecting both p16INK4a and p14ARF.
|
12853981 |
2003 |
|
| Entrez Id: |
1029 |
| Gene Symbol: |
CDKN2A |
CDKN2A
|
MELANOMA-PANCREATIC CANCER SYNDROME
|
0.600 |
GeneticVariation |
CLINVAR |
Familial melanoma, pancreatic cancer and germline CDKN2A mutations.
|
15146471 |
2004 |