×
Entrez Id: 4292
Gene Symbol: MLH1
MLH1
Hereditary Non-Polyposis Colon Cancer Type 2
0.710
GeneticVariation
UNIPROT
Genomic deletions of MSH2 and MLH1 in colorectal cancer families detected by a novel mutation detection approach.
12373605 2002
×
Entrez Id: 4292
Gene Symbol: MLH1
MLH1
Hereditary Non-Polyposis Colon Cancer Type 2
0.710
GeneticVariation
UNIPROT
Germline hMSH2 and hMLH1 gene mutations in incomplete HNPCC families.
9399661 1997
×
Entrez Id: 4292
Gene Symbol: MLH1
MLH1
Hereditary Non-Polyposis Colon Cancer Type 2
0.710
GeneticVariation
UNIPROT
CpG dinucleotides in the hMSH2 and hMLH1 genes are hotspots for HNPCC mutations.
8566964 1996
×
Entrez Id: 4292
Gene Symbol: MLH1
MLH1
Hereditary Non-Polyposis Colon Cancer Type 2
0.710
GeneticVariation
UNIPROT
Mutational analysis of the hMLH1 gene using an automated two-dimensional DNA typing system.
9067757 1997
×
Entrez Id: 4292
Gene Symbol: MLH1
MLH1
Hereditary Non-Polyposis Colon Cancer Type 2
0.710
GeneticVariation
UNIPROT
A human compound heterozygote for two MLH1 missense mutations.
9326924 1997
×
Entrez Id: 4292
Gene Symbol: MLH1
MLH1
Hereditary Non-Polyposis Colon Cancer Type 2
0.710
GeneticVariation
UNIPROT
A large fraction of unclassified variants of the mismatch repair genes MLH1 and MSH2 is associated with splicing defects.
18561205 2008
×
Entrez Id: 4292
Gene Symbol: MLH1
MLH1
Hereditary Non-Polyposis Colon Cancer Type 2
0.710
GeneticVariation
UNIPROT
Genomic deletions in MSH2 or MLH1 are a frequent cause of hereditary non-polyposis colorectal cancer: identification of novel and recurrent deletions by MLPA.
14635101 2003
×
Entrez Id: 4292
Gene Symbol: MLH1
MLH1
Hereditary Non-Polyposis Colon Cancer Type 2
0.710
GeneticVariation
UNIPROT
hMLH1 and hMSH2 mutations in families with familial clustering of gastric cancer and hereditary non-polyposis colorectal cancer.
12132870 2001
×
Entrez Id: 4292
Gene Symbol: MLH1
MLH1
Hereditary Non-Polyposis Colon Cancer Type 2
0.710
GeneticVariation
UNIPROT
Use of SSCP analysis to identify germline mutations in HNPCC families fulfilling the Amsterdam criteria.
9048925 1997
×
Entrez Id: 4292
Gene Symbol: MLH1
MLH1
Hereditary Non-Polyposis Colon Cancer Type 2
0.710
GeneticVariation
UNIPROT
Impact of microsatellite testing and mismatch repair protein expression on the clinical interpretation of genetic testing in hereditary non-polyposis colorectal cancer.
12200596 2002
×
Entrez Id: 4292
Gene Symbol: MLH1
MLH1
Hereditary Non-Polyposis Colon Cancer Type 2
0.710
GeneticVariation
UNIPROT
Functional analysis of MLH1 mutations linked to hereditary nonpolyposis colon cancer.
11793442 2002
×
Entrez Id: 4292
Gene Symbol: MLH1
MLH1
Hereditary Non-Polyposis Colon Cancer Type 2
0.710
GeneticVariation
UNIPROT
Hereditary nonpolyposis colorectal cancer (HNPCC): eight novel germline mutations in hMSH2 or hMLH1 genes.
9298827 1997
×
Entrez Id: 4292
Gene Symbol: MLH1
MLH1
Hereditary Non-Polyposis Colon Cancer Type 2
0.710
GeneticVariation
UNIPROT
The interaction of DNA mismatch repair proteins with human exonuclease I.
11427529 2001
×
Entrez Id: 4292
Gene Symbol: MLH1
MLH1
Hereditary Non-Polyposis Colon Cancer Type 2
0.710
GeneticVariation
UNIPROT
HNPCC mutation MLH1 P648S makes the functional protein unstable, and homozygosity predisposes to mild neurofibromatosis type 1.
15139004 2004
×
Entrez Id: 4292
Gene Symbol: MLH1
MLH1
Hereditary Non-Polyposis Colon Cancer Type 2
0.710
GeneticVariation
UNIPROT
Molecular analysis of hereditary nonpolyposis colorectal cancer in the United States: high mutation detection rate among clinically selected families and characterization of an American founder genomic deletion of the MSH2 gene.
12658575 2003
×
Entrez Id: 4292
Gene Symbol: MLH1
MLH1
Hereditary Non-Polyposis Colon Cancer Type 2
0.710
GeneticVariation
UNIPROT
Mutations of hMLH1 and hMSH2 in patients with suspected hereditary nonpolyposis colorectal cancer: correlation with microsatellite instability and abnormalities of mismatch repair protein expression.
11870161 2002
×
Entrez Id: 4292
Gene Symbol: MLH1
MLH1
Hereditary Non-Polyposis Colon Cancer Type 2
0.710
GeneticVariation
UNIPROT
Ten novel MSH2 and MLH1 germline mutations in families with HNPCC.
15365996 2004
×
Entrez Id: 4292
Gene Symbol: MLH1
MLH1
Hereditary Non-Polyposis Colon Cancer Type 2
0.710
GeneticVariation
UNIPROT
Excess of hMLH1 germline mutations in Swiss families with hereditary non-polyposis colorectal cancer.
9833759 1998
×
Entrez Id: 4292
Gene Symbol: MLH1
MLH1
Hereditary Non-Polyposis Colon Cancer Type 2
0.710
GeneticVariation
UNIPROT
Germline epimutation of MLH1 in individuals with multiple cancers.
15064764 2004
×
Entrez Id: 4292
Gene Symbol: MLH1
MLH1
Hereditary Non-Polyposis Colon Cancer Type 2
0.710
GeneticVariation
UNIPROT
Germline MSH2 and MLH1 mutational spectrum including large rearrangements in HNPCC families from Poland (update study).
16451135 2006
×
Entrez Id: 4292
Gene Symbol: MLH1
MLH1
Hereditary Non-Polyposis Colon Cancer Type 2
0.710
GeneticVariation
UNIPROT
Germline MSH2 and MLH1 mutational spectrum in HNPCC families from Poland and the Baltic States.
12362047 2002
×
Entrez Id: 4292
Gene Symbol: MLH1
MLH1
Hereditary Non-Polyposis Colon Cancer Type 2
0.710
GeneticVariation
UNIPROT
Inheritance of a cancer-associated MLH1 germ-line epimutation.
17301300 2007
×
Entrez Id: 4292
Gene Symbol: MLH1
MLH1
Hereditary Non-Polyposis Colon Cancer Type 2
0.710
GeneticVariation
UNIPROT
Pathogenicity of missense and splice site mutations in hMSH2 and hMLH1 mismatch repair genes: implications for genetic testing.
11839723 2002
×
Entrez Id: 4292
Gene Symbol: MLH1
MLH1
Hereditary Non-Polyposis Colon Cancer Type 2
0.710
GeneticVariation
UNIPROT
Sixteen rare sequence variants of the hMLH1 and hMSH2 genes found in a cohort of 254 suspected HNPCC (hereditary non-polyposis colorectal cancer) patients: mutations or polymorphisms?
11726306 2001
×
Entrez Id: 4292
Gene Symbol: MLH1
MLH1
Hereditary Non-Polyposis Colon Cancer Type 2
0.710
GeneticVariation
UNIPROT
Systematic analysis of hMSH2 and hMLH1 in young colon cancer patients and controls.
9718327 1998